(Q35189383)

7 August 2017

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title

Histone deacetylase inhibitors in cancer therapy: is transcription the primary target? (English)

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7 August 2017

Jonathan D Licht

2

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Ricky W Johnstone

object named as

Ricky W Johnstone

series ordinal

1

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publication date

1 July 2003

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7 August 2017

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7 August 2017

volume

4

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7 August 2017

issue

1

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7 August 2017

page(s)

13-18

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p21(WAF1) is required for butyrate-mediated growth inhibition of human colon cancer cells

7 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016/S1535-6108(03)00165-X

7 January 2021

Depsipeptide (FR901228) induces histone acetylation and inhibition of histone deacetylase in chronic lymphocytic leukemia cells concurrent with activation of caspase 8-mediated apoptosis and down-regulation of c-FLIP protein

1 reference

https://api.crossref.org/works/10.1016/S1535-6108(03)00165-X

7 January 2021

Induction and superinduction of growth arrest and DNA damage gene 45 (GADD45) alpha and beta messenger RNAs by histone deacetylase inhibitors trichostatin A (TSA) and butyrate in SW620 human colon carcinoma cells

1 reference

https://api.crossref.org/works/10.1016/S1535-6108(03)00165-X

7 January 2021

Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2'-deoxycytidine (decitabine) treatment

1 reference

https://api.crossref.org/works/10.1016/S1535-6108(03)00165-X

7 January 2021

Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor

1 reference

https://api.crossref.org/works/10.1016/S1535-6108(03)00165-X

7 January 2021

Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

1 reference

https://api.crossref.org/works/10.1016/S1535-6108(03)00165-X

7 January 2021

Deacetylase enzymes: biological functions and the use of small-molecule inhibitors

1 reference

https://api.crossref.org/works/10.1016/S1535-6108(03)00165-X

7 January 2021

Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation

1 reference

https://api.crossref.org/works/10.1016/S1535-6108(03)00165-X

7 January 2021

Role of caspases, Bid, and p53 in the apoptotic response triggered by histone deacetylase inhibitors trichostatin-A (TSA) and suberoylanilide hydroxamic acid (SAHA).

1 reference

https://api.crossref.org/works/10.1016/S1535-6108(03)00165-X

7 January 2021

HDAC6 is a microtubule-associated deacetylase

1 reference

https://api.crossref.org/works/10.1016/S1535-6108(03)00165-X

7 January 2021

Translating the Histone Code

1 reference

https://api.crossref.org/works/10.1016/S1535-6108(03)00165-X

7 January 2021

Histone-deacetylase inhibitors: novel drugs for the treatment of cancer

1 reference

https://api.crossref.org/works/10.1016/S1535-6108(03)00165-X

7 January 2021

Apoptosis: a link between cancer genetics and chemotherapy

1 reference

https://api.crossref.org/works/10.1016/S1535-6108(03)00165-X

7 January 2021

The fundamental role of epigenetic events in cancer

1 reference

https://api.crossref.org/works/10.1016/S1535-6108(03)00165-X

7 January 2021

Histone deacetylase inhibitors: from target to clinical trials

1 reference

https://api.crossref.org/works/10.1016/S1535-6108(03)00165-X

7 January 2021

Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence

1 reference

https://api.crossref.org/works/10.1016/S1535-6108(03)00165-X

7 January 2021

Histone deacetylases as therapeutic targets in hematologic malignancies

1 reference

https://api.crossref.org/works/10.1016/S1535-6108(03)00165-X

7 January 2021

Molecular sequelae of histone deacetylase inhibition in human malignant B cells

1 reference

https://api.crossref.org/works/10.1016/S1535-6108(03)00165-X

7 January 2021

The human Sir2 ortholog, SIRT2, is an NAD -dependent tubulin deacetylase

1 reference

https://api.crossref.org/works/10.1016/S1535-6108(03)00165-X

7 January 2021

Histone deacetylase inhibitors trigger a G2 checkpoint in normal cells that is defective in tumor cells.

1 reference

https://api.crossref.org/works/10.1016/S1535-6108(03)00165-X

7 January 2021

Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation

1 reference

https://api.crossref.org/works/10.1016/S1535-6108(03)00165-X

7 January 2021

The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species

1 reference

https://api.crossref.org/works/10.1016/S1535-6108(03)00165-X

7 January 2021

Reversible disruption of pericentric heterochromatin and centromere function by inhibiting deacetylases

1 reference

https://api.crossref.org/works/10.1016/S1535-6108(03)00165-X

7 January 2021

Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma.

1 reference

https://api.crossref.org/works/10.1016/S1535-6108(03)00165-X

7 January 2021

10.1016/S1535-6108(03)00165-X

Identifiers

DOI

1 reference

7 August 2017

1 reference