(Q34789093)

4 August 2017

title

CCR3 is essential for skin eosinophilia and airway hyperresponsiveness in a murine model of allergic skin inflammation (English)

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4 August 2017

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3

Alison A Humbles

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4 August 2017

9

Craig Gerard

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4 August 2017

8

Hans C Oettgen

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4 August 2017

10

Raif S Geha

1 reference

4 August 2017

Weilie Ma

1

1 reference

4 August 2017

Paul J Bryce

2

1 reference

4 August 2017

Dhafer Laouini

4

1 reference

4 August 2017

Ali Yalcindag

5

1 reference

4 August 2017

Harri Alenius

6

1 reference

4 August 2017

Daniel S Friend

7

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4 August 2017

language of work or name

English

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publication date

1 March 2002

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Journal of Clinical Investigation

4 August 2017

published in

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4 August 2017

volume

109

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4 August 2017

issue

5

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4 August 2017

page(s)

621-628

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The murine CCR3 receptor regulates both the role of eosinophils and mast cells in allergen-induced airway inflammation and hyperresponsiveness

4 August 2017

cites work

1 reference

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The chemokine receptor CXCR4 is expressed within the mast cell lineage and its ligand stromal cell-derived factor-1alpha acts as a mast cell chemotaxin

8 July 2018

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Senescent jejunal mast cells and eosinophils in the mouse preferentially translocate to the spleen and draining lymph node, respectively, during the recovery phase of helminth infection

8 July 2018

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8 July 2018

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Atopic dermatitis: new insights and opportunities for therapeutic intervention

8 July 2018

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Increased neutrophil numbers and IL-8 levels in airway secretions in acute severe asthma: Clinical and biologic significance

8 July 2018

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8 July 2018

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Lymph node trafficking and antigen presentation by endobronchial eosinophils

8 July 2018

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Th2 responses induced by epicutaneous or inhalational protein exposure are differentially dependent on IL-4.

8 July 2018

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8 July 2018

Chemokines in allergy

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Tryptase-chymase double-positive human mast cells express the eotaxin receptor CCR3 and are attracted by CCR3-binding chemokines

8 July 2018

1 reference

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T helper cell type 2 cytokine-mediated comitogenic responses and CCR3 expression during differentiation of human mast cells in vitro

8 July 2018

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Immunologic basis of antigen-induced airway hyperresponsiveness

8 July 2018

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Roles of TH1 and TH2 cytokines in a murine model of allergic dermatitis.

8 July 2018

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Eotaxin activates T cells to chemotaxis and adhesion only if induced to express CCR3 by IL-2 together with IL-4

8 July 2018

1 reference

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Differential regulation of eosinophil chemokine signaling via CCR3 and non-CCR3 pathways

8 July 2018

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The coordinated action of CC chemokines in the lung orchestrates allergic inflammation and airway hyperresponsiveness

8 July 2018

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Epicutaneous sensitization with protein antigen induces localized allergic dermatitis and hyperresponsiveness to methacholine after single exposure to aerosolized antigen in mice

8 July 2018

1 reference

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Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells

8 July 2018

1 reference

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Interleukin-5 expression in the lung epithelium of transgenic mice leads to pulmonary changes pathognomonic of asthma

8 July 2018

1 reference

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Targeted disruption of the chemokine eotaxin partially reduces antigen-induced tissue eosinophilia

8 July 2018

1 reference

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Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils

8 July 2018

1 reference

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Role of eosinophil-chemotactic C-C chemokines in cutaneous inflammation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150891

Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150891

Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150891

Eosinophils in atopic dermatitis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150891

Atopic dermatitis: the skin as a window into the pathogenesis of chronic allergic diseases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150891

The kinetics of allergen-induced transcription of messenger RNA for monocyte chemotactic protein-3 and RANTES in the skin of human atopic subjects: relationship to eosinophil, T cell, and macrophage recruitment

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150891

Schistosoma mansoni: eosinophilia and the development of lymphocyte blastogenesis in response to soluble egg antigen in inbred mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150891

Immunopathology of atopic dermatitis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150891

Stem cell factor and igE-stimulated murine mast cells produce chemokines (CCL2, CCL17, CCL22) and express chemokine receptors.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150891

Expression of the chemokine receptor CCR3 on human mast cells

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150891

Antigen-induced eosinophilic lung inflammation develops in mice deficient in chemokine eotaxin.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150891

A murine model of allergic rhinitis: studies on the role of IgE in pathogenesis and analysis of the eosinophil influx elicited by allergen and eotaxin

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150891

Enhanced expression of eotaxin and CCR3 mRNA and protein in atopic asthma. Association with airway hyperresponsiveness and predominant co‐localization of eotaxin mRNA to bronchial epithelial and endothelial cells

26 October 2018

1 reference

12 December 2020

Eotaxin induces a rapid release of eosinophils and their progenitors from the bone marrow

1 reference

12 December 2020

Macrophage-derived chemokine induces human eosinophil chemotaxis in a CC chemokine receptor 3– and CC chemokine receptor 4–independent manner

1 reference

12 December 2020

Enhanced expression of eotaxin and CCR3 in atopic dermatitis

1 reference

12 December 2020

Increased levels in vivo of mRNAs for IL-8 and macrophage inflammatory protein-1 alpha (MIP-1 alpha), but not of RANTES mRNA in peripheral blood mononuclear cells of patients with atopic dermatitis (AD)

1 reference

12 December 2020

Mast cells regulate IFN-gamma expression in the skin and circulating IgE levels in allergen-induced skin inflammation

1 reference

12 December 2020

Immunofluorescence identification of eosinophil granule major basic protein in the flame figures of Wells' syndrome

1 reference

12 December 2020

Dermal deposition of eosinophil-granule major basic protein in atopic dermatitis. Comparison with onchocerciasis

1 reference

12 December 2020

Sensitivity and specificity of bronchial provocation testing. An evaluation of four techniques in exercise-induced bronchospasm

1 reference

12 December 2020

Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice

1 reference

12 December 2020

Assessment of eosinophil and neutrophil participation in atopic dermatitis: comparison with the IgE-mediated late-phase reaction

1 reference

12 December 2020

Interleukin-8 is a potent mediator of eosinophil chemotaxis through endothelium and epithelium

1 reference

12 December 2020

IL‐5, IL‐8 and GM‐CSF immunostaining of sputum cells in bronchial asthma and chronic bronchitis

1 reference

12 December 2020

Increased MCP-1, RANTES, and MIP-1alpha in bronchoalveolar lavage fluid of allergic asthmatic patients

1 reference

12 December 2020

Biphasic response against aeroallergen in atopic dermatitis showing a switch from an initial TH2 response to a TH1 response in situ: an immunocytochemical study

1 reference

12 December 2020

Constitutive production of IL-4 and IL-10 and stimulated production of IL-8 by normal peripheral blood eosinophils

1 reference

12 December 2020

The expression of murine cutaneous late phase reaction requires both IgE antibodies and CD4 T cells

1 reference

12 December 2020

Monocyte chemotactic protein-3 (MCP-3)/fibroblast-induced cytokine (FIC) in eosinophilic inflammation of the airways and the inhibitory effects of an anti-MCP-3/FIC antibody

1 reference

12 December 2020

Noninvasive Measurement of Airway Responsiveness in Allergic Mice Using Barometric Plethysmography

1 reference

12 December 2020

Delayed eosinophil programmed cell death in vitro: a common feature of inhalant allergy and extrinsic and intrinsic atopic dermatitis

1 reference

12 December 2020

Cytokine expression during allergen-induced late nasal responses: IL-4 and IL-5 mRNA is expressed early (at 6 h) predominantly by eosinophils

1 reference

12 December 2020

An obligate role for T-cell receptor alphabeta T cells but not T-cell receptor gammadelta T cells, B cells, or CD40/CD40L interactions in a mouse model of atopic dermatitis

1 reference

12 December 2020

IL-13 induces airways hyperreactivity independently of the IL-4R alpha chain in the allergic lung

1 reference

12 December 2020

Critical role for IL-13 in the development of allergen-induced airway hyperreactivity

1 reference

12 December 2020

Release of RANTES, MIP-1 α , and MCP-1 into Asthmatic Airways Following Endobronchial Allergen Challenge

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI0214097

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4 August 2017

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4 August 2017

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