(Q34718087)

4 August 2017

0 references

Cyclin-G-associated kinase modifies α-synuclein expression levels and toxicity in Parkinson's disease: results from the GenePD Study (English)

1 reference

4 August 2017

1 reference

1 reference

9

Susan Lindquist

1 reference

4 August 2017

Alexandra Dumitriu

1

0 references

Jeanne C Latourelle

Jeanne C Latourelle

5

0 references

Stefano Goldwurm

Stefano Goldwurm

6

0 references

Richard H Myers

Richard H Myers

10

0 references

Gianni Pezzoli

7

Gianni Pezzoli

1 reference

4 August 2017

Chris D Pacheco

2

1 reference

4 August 2017

Jemma B Wilk

3

1 reference

4 August 2017

Katherine E Strathearn

4

1 reference

4 August 2017

Jean-Christophe Rochet

8

1 reference

4 August 2017

publication date

21 January 2011

1 reference

4 August 2017

published in

Human Molecular Genetics

1 reference

4 August 2017

volume

20

1 reference

4 August 2017

issue

8

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4 August 2017

page(s)

1478-1487

1 reference

describes a project that uses

4 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3063983/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease

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Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease

7 July 2018

1 reference

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Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson's disease models

7 July 2018

1 reference

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An abundance of ubiquitously expressed genes revealed by tissue transcriptome sequence data

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063983

Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease

7 July 2018

1 reference

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Genome-wide association study reveals genetic risk underlying Parkinson's disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063983

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

7 July 2018

1 reference

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Cathepsin D expression level affects alpha-synuclein processing, aggregation, and toxicity in vivo.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063983

Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063983

Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity

7 July 2018

1 reference

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Genomewide association study for susceptibility genes contributing to familial Parkinson disease

7 July 2018

1 reference

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Cathepsin D is the main lysosomal enzyme involved in the degradation of alpha-synuclein and generation of its carboxy-terminally truncated species

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063983

Methionine sulfoxide reductase A protects dopaminergic cells from Parkinson's disease-related insults

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063983

Curcumin inhibits aggregation of alpha-synuclein

7 July 2018

1 reference

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The Parkinson's disease protein alpha-synuclein disrupts cellular Rab homeostasis

7 July 2018

1 reference

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PLINK: a tool set for whole-genome association and population-based linkage analyses

7 July 2018

1 reference

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Canonical interaction of cyclin G associated kinase with adaptor protein 1 regulates lysosomal enzyme sorting

7 July 2018

1 reference

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Genome-wide genotyping in Parkinson's disease and neurologically normal controls: first stage analysis and public release of data

7 July 2018

1 reference

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A burst of auxilin recruitment determines the onset of clathrin-coated vesicle uncoating

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063983

Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063983

High-resolution whole-genome association study of Parkinson disease.

7 July 2018

1 reference

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Alpha-synuclein locus duplication as a cause of familial Parkinson's disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063983

alpha-Synuclein locus triplication causes Parkinson's disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063983

CK2 and GAK/auxilin2 are major protein kinases in clathrin-coated vesicles

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063983

Segregation analysis of Parkinson disease revealing evidence for a major causative gene.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063983

Tetrahydrobiopterin scavenges superoxide in dopaminergic neurons

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063983

Alpha-synuclein and neurodegenerative diseases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063983

Identification of the universal cofactor (auxilin 2) in clathrin coat dissociation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063983

Role of Cyclin G-associated Kinase in Uncoating Clathrin-coated Vesicles from Non-neuronal Cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063983

Clathrin assembly lymphoid myeloid leukemia (CALM) protein: localization in endocytic-coated pits, interactions with clathrin, and the impact of overexpression on clathrin-mediated traffic

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063983

Some comments on frequently used multiple endpoint adjustment methods in clinical trials

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063983

Dynamic Imaging of Purified Individual Synaptic Vesicles

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063983

α-Synuclein in Lewy bodies

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063983

GAK: a cyclin G associated kinase contains a tensin/auxilin-like domain

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063983

The future of genetic studies of complex human diseases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063983

A clinical genetic study of Parkinson's disease: evidence for dominant transmission

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063983

Ageing and Parkinson's disease: substantia nigra regional selectivity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063983

Yeast cells provide insight into alpha-synuclein biology and pathobiology

7 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093/HMG/DDR026

Quality control for microarray analysis of human brain samples: The impact of postmortem factors, RNA characteristics, and histopathology

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093/HMG/DDR026

Mechanisms of DJ-1 neuroprotection in a cellular model of Parkinson's disease

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063983

26 October 2018

1 reference

12 December 2020

Causal relation between alpha-synuclein gene duplication and familial Parkinson's disease

1 reference

12 December 2020

Increased risk of Parkinson's disease in parents and siblings of patients

1 reference

12 December 2020

The relative importance of premortem acidosis and postmortem interval for human brain gene expression studies: selective mRNA vulnerability and comparison with their encoded proteins

1 reference

12 December 2020

Gene expression profiling of parkinsonian substantia nigra pars compacta; alterations in ubiquitin-proteasome, heat shock protein, iron and oxidative stress regulated proteins, cell adhesion/cellular matrix and vesicle trafficking genes

1 reference

12 December 2020

Recruitment dynamics of GAK and auxilin to clathrin-coated pits during endocytosis

1 reference

12 December 2020

Identifiers

DOI

10.1093/HMG/DDR026

1 reference

4 August 2017

1 reference

4 August 2017

1 reference