(Q34395659)

1 August 2017

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title

p53 in signaling checkpoint arrest or apoptosis (English)

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1 August 2017

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Bates S

1

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1 August 2017

Vousden KH

series ordinal

2

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1 August 2017

publication date

1 February 1996

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Current Opinion in Genetics & Development

1 August 2017

published in

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1 August 2017

volume

6

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1 August 2017

issue

1

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1 August 2017

page(s)

12-18

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Cancer. p53, guardian of the genome

1 August 2017

cites work

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7 January 2021

Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1

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7 January 2021

Accumulation of wild-type p53 protein upon gamma-irradiation induces a G2 arrest-dependent immunoglobulin kappa light chain gene expression.

1 reference

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7 January 2021

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

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7 January 2021

Mediation of c-Myc-induced apoptosis by p53.

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7 January 2021

p53 is required for radiation-induced apoptosis in mouse thymocytes

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7 January 2021

Thymocyte apoptosis induced by p53-dependent and independent pathways.

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7 January 2021

Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.

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7 January 2021

p53-dependent apoptosis suppresses tumor growth and progression in vivo

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7 January 2021

Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: implications for tumor suppressor gene function in development

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7 January 2021

Apoptosis or retinoblastoma: alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53

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7 January 2021

p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens.

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7 January 2021

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

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7 January 2021

DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts

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7 January 2021

A p53-dependent mouse spindle checkpoint

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7 January 2021

Transcriptional activation by p53 correlates with suppression of growth but not transformation.

1 reference

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7 January 2021

Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutant

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7 January 2021

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7 January 2021

Radiation-induced cell cycle arrest compromised by p21 deficiency

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7 January 2021

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

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7 January 2021

Induction of cellular p53 activity by DNA-damaging agents and growth arrest.

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7 January 2021

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

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7 January 2021

Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen

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7 January 2021

Cip1 inhibits DNA replication but not PCNA-dependent nucleotide excision-repair

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7 January 2021

mdm2 expression is induced by wild type p53 activity

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7 January 2021

The p53-mdm-2 autoregulatory feedback loop

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7 January 2021

Essential role for p53-mediated transcription in E1A-induced apoptosis

1 reference

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7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

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7 January 2021

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

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7 January 2021

Growth factor modulation of p53-mediated growth arrest versus apoptosis

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7 January 2021

DNA damage in human B cells can induce apoptosis, proceeding from G1/S when p53 is transactivation competent and G2/M when it is transactivation defective.

1 reference

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7 January 2021

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

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7 January 2021

Premature p34cdc2 activation required for apoptosis.

1 reference

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7 January 2021

Induction of the growth inhibitor IGF-binding protein 3 by p53

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7 January 2021

Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(96)95004-0

7 January 2021

c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines.

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(96)95004-0

7 January 2021

p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(96)95004-0

7 January 2021

Induction of apoptosis in HeLa cells by trans-activation-deficient p53

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https://api.crossref.org/works/10.1016/S0959-437X(96)95004-0

7 January 2021

Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis

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https://api.crossref.org/works/10.1016/S0959-437X(96)95004-0

7 January 2021

The WT1 gene product stabilizes p53 and inhibits p53-mediated apoptosis

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https://api.crossref.org/works/10.1016/S0959-437X(96)95004-0

7 January 2021

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

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7 January 2021

Interleukin 3 protects murine bone marrow cells from apoptosis induced by DNA damaging agents

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7 January 2021

Activated H-ras rescues E1A-induced apoptosis and cooperates with E1A to overcome p53-dependent growth arrest

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(96)95004-0

7 January 2021

Complementation by wild-type p53 of interleukin-6 effects on M1 cells: induction of cell cycle exit and cooperativity with c-myc suppression

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(96)95004-0

7 January 2021

Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(96)95004-0

7 January 2021

10.1016/S0959-437X(96)95004-0

Identifiers

DOI

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1 August 2017

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