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Thinking outside of the "RGS box": new approaches to therapeutic targeting of regulators of G protein signaling.
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Europe PubMed Central
PMC publication ID
2981398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20664002 AND SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
review article
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Europe PubMed Central
title
Thinking outside of the "RGS box": new approaches to therapeutic targeting of regulators of G protein signaling
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2981398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20664002 AND SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
author
Richard Neubig
series ordinal
2
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stated in
Europe PubMed Central
PMC publication ID
2981398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20664002 AND SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
author name string
Benita Sjögren
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
2981398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20664002 AND SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
publication date
27 July 2010
1 reference
stated in
Europe PubMed Central
PMC publication ID
2981398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20664002 AND SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
published in
Molecular Pharmacology
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stated in
Europe PubMed Central
PMC publication ID
2981398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20664002 AND SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
volume
78
1 reference
stated in
Europe PubMed Central
PMC publication ID
2981398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20664002 AND SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
issue
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
2981398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20664002 AND SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
page(s)
550-557
1 reference
stated in
Europe PubMed Central
PMC publication ID
2981398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20664002 AND SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
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The Gbeta5-RGS7 complex selectively inhibits muscarinic M3 receptor signaling via the interaction between the third intracellular loop of the receptor and the DEP domain of RGS7
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6 July 2018
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6 July 2018
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6 July 2018
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6 July 2018
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6 July 2018
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6 July 2018
Src-mediated RGS16 tyrosine phosphorylation promotes RGS16 stability
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6 July 2018
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6 July 2018
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6 July 2018
An essential role of N-terminal arginylation in cardiovascular development
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PIP3 inhibition of RGS protein and its reversal by Ca2 /calmodulin mediate voltage-dependent control of the G protein cycle in a cardiac K channel
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Ca(2 ) elevation evoked by membrane depolarization regulates G protein cycle via RGS proteins in the heart
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Regulator of G protein signaling proteins: novel multifunctional drug targets
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6 July 2018
GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins
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6 July 2018
RGS4 is arginylated and degraded by the N-end rule pathway in vitro
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6 July 2018
Ca2 /Calmodulin reverses phosphatidylinositol 3,4, 5-trisphosphate-dependent inhibition of regulators of G protein-signaling GTPase-activating protein activity
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6 July 2018
Emerging roles for RGS proteins in cell signalling
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6 July 2018
The ubiquitin system
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6 July 2018
RGS2/G0S8 is a selective inhibitor of Gqα function
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6 July 2018
Regulators of G-Protein Signaling (RGS) Proteins: Region-Specific Expression of Nine Subtypes in Rat Brain
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retrieved
6 July 2018
Structure of RGS4 bound to AlF4--activated G(i alpha1): stabilization of the transition state for GTP hydrolysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981398
retrieved
6 July 2018
A mouse amidase specific for N-terminal asparagine. The gene, the enzyme, and their function in the N-end rule pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981398
retrieved
6 July 2018
The N-end rule: functions, mysteries, uses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981398
retrieved
6 July 2018
RGS9-2 negatively modulates L-3,4-dihydroxyphenylalanine-induced dyskinesia in experimental Parkinson's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981398
retrieved
28 October 2018
Expression and localization of RGS9-2/G 5/R7BP complex in vivo is set by dynamic control of its constitutive degradation by cellular cysteine proteases.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981398
retrieved
28 October 2018
Endogenous RGS proteins modulate SA and AV nodal functions in isolated heart: implications for sick sinus syndrome and AV block.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981398
retrieved
28 October 2018
Mechanism of action and structural requirements of constrained peptide inhibitors of RGS proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981398
retrieved
28 October 2018
RGS2 is upregulated by and attenuates the hypertrophic effect of alpha1-adrenergic activation in cultured ventricular myocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981398
retrieved
28 October 2018
Endogenous RGS proteins and Galpha subtypes differentially control muscarinic and adenosine-mediated chronotropic effects.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981398
retrieved
28 October 2018
Selective loss of fine tuning of Gq/11 signaling by RGS2 protein exacerbates cardiomyocyte hypertrophy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981398
retrieved
28 October 2018
Yeast-based screening for inhibitors of RGS proteins.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981398
retrieved
28 October 2018
Structure-based design, synthesis, and pharmacologic evaluation of peptide RGS4 inhibitors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981398
retrieved
28 October 2018
Regulation of RGS proteins by chronic morphine in rat locus coeruleus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981398
retrieved
28 October 2018
Oxidative stress and heat shock stimulate RGS2 expression in 1321N1 astrocytoma cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981398
retrieved
28 October 2018
RGS4 binds to membranes through an amphipathic alpha -helix.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981398
retrieved
28 October 2018
Regulator of G-protein signaling 2 (RGS2) inhibits androgen-independent activation of androgen receptor in prostate cancer cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20664002
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Regulator of G protein signaling 8 (RGS8) requires its NH2 terminus for subcellular localization and acute desensitization of G protein-gated K channels
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20664002
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1124/MOL.110.065219
1 reference
stated in
Europe PubMed Central
PMC publication ID
2981398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20664002 AND SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
PMC publication ID
2981398
1 reference
stated in
Europe PubMed Central
PMC publication ID
2981398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20664002 AND SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
PubMed publication ID
20664002
1 reference
stated in
Europe PubMed Central
PMC publication ID
2981398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20664002 AND SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
ResearchGate publication ID
45388958
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