(Q34152769)

31 July 2017

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title

Clinical translation of angiogenesis inhibitors (English)

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31 July 2017

main subject

angiogenesis inhibitor

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2

Judah Folkman

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31 July 2017

Robert Kerbel

1

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31 July 2017

language of work or name

English

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publication date

1 October 2002

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31 July 2017

published in

Nature Reviews Cancer

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31 July 2017

volume

2

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31 July 2017

issue

10

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31 July 2017

page(s)

727-739

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31 July 2017

cites work

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Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

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Oncogenes and angiogenesis: signaling three-dimensional tumor growth

31 March 2020

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Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

31 March 2020

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Tumor induction of VEGF promoter activity in stromal cells

31 March 2020

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Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1

31 March 2020

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Inhibition of tumor angiogenesis as a strategy to circumvent acquired resistance to anti-cancer therapeutic agents

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Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance

31 March 2020

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Angiogenic potential of prostate carcinoma cells overexpressing bcl-2.

31 March 2020

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Oncogenic H-ras stimulates tumor angiogenesis by two distinct pathways

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Essential role for oncogenic Ras in tumour maintenance

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Persistence of microscopic human cancers in mice: alterations in the angiogenic balance accompanies loss of tumor dormancy

31 March 2020

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Downmodulation of bFGF-binding protein expression following restoration of p53 function

31 March 2020

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Tumour biology: herceptin acts as an anti-angiogenic cocktail.

31 March 2020

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Thrombospondin-2: a potent endogenous inhibitor of tumor growth and angiogenesis

31 March 2020

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Regulation of angiogenesis by the C-X-C chemokines interleukin-8 and epithelial neutrophil activating peptide 78 in the rheumatoid joint

31 March 2020

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Antiangiogenic therapy of a recurrent giant cell tumor of the mandible with interferon alfa-2a.

31 March 2020

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Successful antiangiogenic therapy of giant cell angioblastoma with interferon alfa 2b: report of 2 cases

31 March 2020

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Interferons alpha and beta down-regulate the expression of basic fibroblast growth factor in human carcinomas

31 March 2020

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Inhibition of Cell Motility by Interferon

31 March 2020

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Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth

31 March 2020

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Methionine aminopeptidase (type 2) is the common target for angiogenesis inhibitors AGM-1470 and ovalicin.

31 March 2020

1 reference

The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2

31 March 2020

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Complete remission of metastatic cervical cancer with the angiogenesis inhibitor TNP-470

31 March 2020

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Multi-institutional study of the angiogenesis inhibitor TNP-470 in metastatic renal carcinoma

31 March 2020

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Fumagillin analog in the treatment of Kaposi's sarcoma: a phase I AIDS Clinical Trial Group study. AIDS Clinical Trial Group No. 215 Team

31 March 2020

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Delivery of novel therapeutic agents in tumors: physiological barriers and strategies

31 March 2020

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Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

31 March 2020

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Hypoxic induction of vascular endothelial growth factor (VEGF) in human epithelial cells is mediated by increases in mRNA stability

31 March 2020

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Dormancy of micrometastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppression

31 March 2020

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Combined effects of angiostatin and ionizing radiation in antitumour therapy

31 March 2020

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Potentiation of cytotoxic cancer therapies by TNP-470 alone and with other anti-angiogenic agents

31 March 2020

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Normalizing tumor vasculature with anti-angiogenic therapy: a new paradigm for combination therapy

31 March 2020

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8:45-9:00. Using PET 18F-FDG, 11CO, and 15O-water for Monitoring Prostate Cancer During a Phase II Anti-angiogenic Drug Trial with Thalidomide

31 March 2020

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Special techniques for imaging blood flow to tumors.

31 March 2020

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Consequences of angiogenesis for tumor progression, metastasis and cancer therapy.

31 March 2020

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Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

31 March 2020

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Heterogeneous vascular dependence of tumor cell populations

31 March 2020

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Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

31 March 2020

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A comprehensive system to explore p53 mutations

31 March 2020

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Effect of antiangiogenic therapy on slowly growing, poorly vascularized tumors in mice

31 March 2020

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Growth of a local tumor exerts a specific inhibitory effect on progression of lung metastases

31 March 2020

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Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a lewis lung carcinoma

31 March 2020

1 reference

Phosphoglycerate kinase acts in tumour angiogenesis as a disulphide reductase

31 March 2020

1 reference

Endostatin: an endogenous inhibitor of angiogenesis and tumor growth

31 March 2020

1 reference

Secreted cathepsin L generates endostatin from collagen XVIII

31 March 2020

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Antiangiogenic activity of the cleaved conformation of the serpin antithrombin

31 March 2020

1 reference

Analysis of experimental antiangiogenic therapy

31 March 2020

1 reference

Increased growth and incidence of lymph node metastases due to the angiogenesis inhibitor AGM-1470

31 March 2020

1 reference

Possible mechanisms of acquired resistance to anti-angiogenic drugs: implications for the use of combination therapy approaches.

31 March 2020

1 reference

Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity

31 March 2020

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Weekly doxorubicin and continuous infusional 5-fluorouracil for advanced breast cancer

31 March 2020

1 reference

Phase III study of bolus versus infusion fluorouracil with or without cisplatin in advanced colorectal cancer

31 March 2020

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Treatment of non-small-cell lung cancer with prolonged oral etoposide

31 March 2020

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Recurrent supratentorial malignant gliomas in children. Long-term salvage therapy with oral etoposide

31 March 2020

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Less is more, regularly: metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice

31 March 2020

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Novel use of an established agent: Topotecan is anti-angiogenic in experimental Wilms tumor

31 March 2020

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Tumor Growth and Neovascularization: An Experimental Model Using the Rabbit Cornea 2

31 March 2020

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Thalidomide is an inhibitor of angiogenesis

31 March 2020

1 reference

Combination oral antiangiogenic therapy with thalidomide and sulindac inhibits tumour growth in rabbits

31 March 2020

1 reference

Antitumor activity of thalidomide in refractory multiple myeloma

31 March 2020

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Thalidomide in the treatment of relapsed multiple myeloma

31 March 2020

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Successful treatment of multiple myeloma relapsing after high-dose therapy and autologous transplantation with thalidomide as a single agent

31 March 2020

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Thalidomide reduces tumour necrosis factor alpha and interleukin 12 production in patients with chronic active Crohn's disease

31 March 2020

1 reference

Mechanism of action of thalidomide and 3-aminothalidomide in multiple myeloma.

31 March 2020

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Angiogenesis-dependent diseases

31 March 2020

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Thalidomide in multiple myeloma, myelodysplastic syndromes and histiocytosis. Analysis of clinical results and of surrogate angiogenesis markers

31 March 2020

1 reference

Thalidomide--a revival story

31 March 2020

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Tumor angiogenesis and metastasis--correlation in invasive breast carcinoma

31 March 2020

1 reference

Bone marrow angiogenesis in patients achieving complete response after stem cell transplantation for multiple myeloma

31 March 2020

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Clinical application of antiangiogenic therapy: microvessel density, what it does and doesn't tell us.

31 March 2020

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Involvement of platelets in tumour angiogenesis?

31 March 2020

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Microvascular injury in pathogenesis of interferon-induced necrosis of subcutaneous tumors in mice.

31 March 2020

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Cellular markers that distinguish the phases of hemangioma during infancy and childhood

31 March 2020

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Treatment of pulmonary hemangiomatosis with recombinant interferon alfa-2a

31 March 2020

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Successful treatment of an angiogenic disease

31 March 2020

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Interferon alfa-2a therapy for life-threatening hemangiomas of infancy

31 March 2020

1 reference

Butyrate in the treatment of sickle cell disease and β-thalassemia

31 March 2020

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Antiangiogenic therapy with interferon alpha for giant cell lesions of the jaws

31 March 2020

1 reference

Hemangioendothelioma: successful therapy with interferon-alpha: a study in Association with the Italian Pediatric Haematology/Oncology Society (AIEOP)

31 March 2020

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Systemic inhibition of tumor growth and tumor metastases by intramuscular administration of the endostatin gene

31 March 2020

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Local endostatin treatment of gliomas administered by microencapsulated producer cells

31 March 2020

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Continuous release of endostatin from microencapsulated engineered cells for tumor therapy

31 March 2020

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Comparative evaluation of the antitumor activity of antiangiogenic proteins delivered by gene transfer

31 March 2020

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Effect of retroviral endostatin gene transfer on subcutaneous and intraperitoneal growth of murine tumors

31 March 2020

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Combination angiostatin and endostatin gene transfer induces synergistic antiangiogenic activity in vitro and antitumor efficacy in leukemia and solid tumors in mice

31 March 2020

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Adeno-associated virus-mediated gene transfer of endostatin inhibits angiogenesis and tumor growth in vivo

31 March 2020

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Differential effects of angiostatin, endostatin and interferon-alpha(1) gene transfer on in vivo growth of human breast cancer cells.

31 March 2020

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Continuous intravascular secretion of endostatin in mice from transduced hematopoietic stem cells

31 March 2020

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Unfulfilled promise of endostatin in a gene therapy-xenotransplant model of human acute lymphocytic leukemia

31 March 2020

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Elevated levels of an angiogenic peptide, basic fibroblast growth factor, in the urine of patients with a wide spectrum of cancers

31 March 2020

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Bone marrow angiogenesis and progression in multiple myeloma.

31 March 2020

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Bone marrow angiogenesis and mast cell density increase simultaneously with progression of human multiple myeloma.

31 March 2020

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Angiogenesis in B cell lymphoproliferative diseases. Biological and clinical studies

31 March 2020

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Measurement of the grade of vascularisation in histological tumour tissue sections

31 March 2020

1 reference

Heterogeneity of angiogenic activity in a human liposarcoma: a proposed mechanism for "no take" of human tumors in mice

31 March 2020

1 reference

Angiostatin binds ATP synthase on the surface of human endothelial cells

31 March 2020

1 reference

Angiomotin: an angiostatin binding protein that regulates endothelial cell migration and tube formation

31 March 2020

1 reference

Canstatin, a novel matrix-derived inhibitor of angiogenesis and tumor growth

31 March 2020

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The tumor vascular targeting agent combretastatin A-4-phosphate induces reorganization of the actin cytoskeleton and early membrane blebbing in human endothelial cells

31 March 2020

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Identification of the anti-angiogenic site within vascular basement membrane-derived tumstatin

31 March 2020

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Tumstatin, an endothelial cell-specific inhibitor of protein synthesis

31 March 2020

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Oncogenes as inducers of tumor angiogenesis

31 March 2020

1 reference

Both v-Ha-Ras and v-Raf Stimulate Expression of the Vascular Endothelial Growth Factor in NIH 3T3 Cells

31 March 2020

1 reference

Expression of the extracellular matrix molecule thrombospondin inversely correlates with malignant progression in melanoma, lung and breast carcinoma cell lines

31 March 2020

1 reference

Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation

31 March 2020

1 reference

Myb-dependent regulation of thrombospondin 2 expression. Role of mRNA stability

31 March 2020

1 reference

Tumor angiogenesis correlates with metastatic disease, N-myc amplification, and poor outcome in human neuroblastoma

31 March 2020

1 reference

Down-regulation of endothelial cell growth inhibitors by enhanced MYCN oncogene expression in human neuroblastoma cells.

31 March 2020

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Reversible activation of c-Myc in skin: induction of a complex neoplastic phenotype by a single oncogenic lesion

31 March 2020

1 reference

Repression of thrombospondin-1 expression, a natural inhibitor of angiogenesis, in polyoma middle T transformed NIH3T3 cells

31 March 2020

1 reference

c-fos is required for malignant progression of skin tumors.

31 March 2020

1 reference

Roles of trk family neurotrophin receptors in medullary thyroid carcinoma development and progression

31 March 2020

1 reference

HPV-16 E7 but not E6 oncogenic protein triggers both cellular immunosuppression and angiogenic processes

31 March 2020

1 reference

Oncogenes and tumor angiogenesis: the HPV-16 E6 oncoprotein activates the vascular endothelial growth factor (VEGF) gene promoter in a p53 independent manner

31 March 2020

1 reference

Phosphatidylinositol 3-kinase signaling mediates angiogenesis and expression of vascular endothelial growth factor in endothelial cells

31 March 2020

1 reference

Early involvement of estrogen-induced pituitary tumor transforming gene and fibroblast growth factor expression in prolactinoma pathogenesis

31 March 2020

1 reference

mAngiogenin-3, a target gene of oncoprotein E2a-Pbx1, encodes a new angiogenic member of the angiogenin family

31 March 2020

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Concomitant Tumor Immunity and the Resistance to a Second Tumor Challenge

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRC905

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Dimensions Publication ID

31 July 2017

1017804909

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