(Q33976667)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15021886 AND SRC:MED&resulttype=core&format=json

25 December 2019

review article

1 reference

title

Nedd8 on cullin: building an expressway to protein destruction (English)

1 reference

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25 December 2019

2

1 reference

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25 December 2019

author name string

Zhen-Qiang Pan

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15021886 AND SRC:MED&resulttype=core&format=json

25 December 2019

Dora C Dias

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15021886 AND SRC:MED&resulttype=core&format=json

25 December 2019

Kosj Yamoah

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15021886 AND SRC:MED&resulttype=core&format=json

25 December 2019

Kenneth Wu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15021886 AND SRC:MED&resulttype=core&format=json

25 December 2019

language of work or name

English

0 references

publication date

1 March 2004

1 reference

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25 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15021886 AND SRC:MED&resulttype=core&format=json

25 December 2019

volume

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15021886 AND SRC:MED&resulttype=core&format=json

25 December 2019

issue

11

1 reference

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25 December 2019

page(s)

1985-1997

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15021886 AND SRC:MED&resulttype=core&format=json

Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis

25 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box

21 January 2018

1 reference

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Conservation in the Mechanism of Nedd8 Activation by the Human AppBp1-Uba3 Heterodimer

21 January 2018

1 reference

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Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase

21 January 2018

1 reference

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The Doc1 subunit is a processivity factor for the anaphase-promoting complex.

21 January 2018

1 reference

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21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

The conserved RING-H2 finger of ROC1 is required for ubiquitin ligation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

UV-damaged DNA-binding proteins are targets of CUL-4A-mediated ubiquitination and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

APP-BP1, a novel protein that binds to the carboxyl-terminal region of the amyloid precursor protein

21 January 2018

1 reference

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Emerging roles of ubiquitin in transcription regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

COP9 signalosome: a multifunctional regulator of SCF and other cullin-based ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

AXR1-ECR1-dependent conjugation of RUB1 to the Arabidopsis Cullin AtCUL1 is required for auxin response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

The ubiquitin-related protein RUB1 and auxin response in Arabidopsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Exclusion of germ plasm proteins from somatic lineages by cullin-dependent degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

The RUB/Nedd8 conjugation pathway is required for early development in Arabidopsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

CUL7: A DOC domain-containing cullin selectively binds Skp1.Fbx29 to form an SCF-like complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

The COP9 Signalosome Promotes Degradation of Cyclin E during Early Drosophila Oogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

A Complex of Cdc4p, Skp1p, and Cdc53p/Cullin Catalyzes Ubiquitination of the Phosphorylated CDK Inhibitor Sic1p

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

CUL-2 is required for the G1-to-S-phase transition and mitotic chromosome condensation in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Targeting of protein ubiquitination by BTB–Cullin 3–Roc1 ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Activation of UBC5 ubiquitin-conjugating enzyme by the RING finger of ROC1 and assembly of active ubiquitin ligases by all cullins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

The CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Identification and characterization of DEN1, a deneddylase of the ULP family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Identification of a novel isopeptidase with dual specificity for ubiquitin- and NEDD8-conjugated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

The ts41 mutation in Chinese hamster cells leads to successive S phases in the absence of intervening G2, M, and G1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Covalent modification of all members of human cullin family proteins by NEDD8

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

The NED-8 conjugating system in Caenorhabditis elegans is required for embryogenesis and terminal differentiation of the hypodermis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Targeting of NEDD8 and its conjugates for proteasomal degradation by NUB1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Muf1, a novel Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

NEDD8 recruits E2-ubiquitin to SCF E3 ligase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

NUB1, a NEDD8-interacting protein, is induced by interferon and down-regulates the NEDD8 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Apc10 and Ste9/Srw1, two regulators of the APC-cyclosome, as well as the CDK inhibitor Rum1 are required for G1 cell-cycle arrest in fission yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Cytoskeletal regulation by the Nedd8 ubiquitin-like protein modification pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

CUL-4A is critical for early embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

A new protease required for cell-cycle progression in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

A novel protein modification pathway related to the ubiquitin system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Rub1p processing by Yuh1p is required for wild-type levels of Rub1p conjugation to Cdc53p

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Cop9/signalosome subunits and Pcu4 regulate ribonucleotide reductase by both checkpoint-dependent and -independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Disruption of the COP9 signalosome Csn2 subunit in mice causes deficient cell proliferation, accumulation of p53 and cyclin E, and early embryonic death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

NEDP1, a highly conserved cysteine protease that deNEDDylates Cullins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

A role for Saccharomyces cerevisiae Cul8 ubiquitin ligase in proper anaphase progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

TIP120A associates with cullins and modulates ubiquitin ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

beta-catenin signaling and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Modification of cullin-1 by ubiquitin-like protein Nedd8 enhances the activity of SCF(skp2) toward p27(kip1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Nedd8-modification of Cul1 is promoted by Roc1 as a Nedd8-E3 ligase and regulates its stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

The Caenorhabditis elegans Skp1-related gene family: diverse functions in cell proliferation, morphogenesis, and meiosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Parc: a cytoplasmic anchor for p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

An intact NEDD8 pathway is required for Cullin-dependent ubiquitylation in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

A new NEDD8-ligating system for cullin-4A

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Preferential interaction of TIP120A with Cul1 that is not modified by NEDD8 and not associated with Skp1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Distinct protein degradation mechanisms mediated by Cul1 and Cul3 controlling Ci stability in Drosophila eye development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Doc1 mediates the activity of the anaphase-promoting complex by contributing to substrate recognition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Mechanisms underlying ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Neddylation and deneddylation of CUL-3 is required to target MEI-1/Katanin for degradation at the meiosis-to-mitosis transition in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

The BTB protein MEL-26 is a substrate-specific adaptor of the CUL-3 ubiquitin-ligase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

A Nedd8 conjugation pathway is essential for proteolytic targeting of p27Kip1 by ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Nedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Cullin 4A associates with the UV-damaged DNA-binding protein DDB

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

F-Box Proteins Are Receptors that Recruit Phosphorylated Substrates to the SCF Ubiquitin-Ligase Complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

The NEDD8 system is essential for cell cycle progression and morphogenetic pathway in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Simian virus 40 large T antigen binds a novel Bcl-2 homology domain 3-containing proapoptosis protein in the cytoplasm.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Cleavage of the C-terminus of NEDD8 by UCH-L3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Identification of NEDD8-conjugation site in human cullin-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Insights into the ubiquitin transfer cascade from the structure of the activating enzyme for NEDD8

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

CSN1 N-terminal-dependent activity is required for Arabidopsis development but not for Rub1/Nedd8 deconjugation of cullins: a structure-function study of CSN1 subunit of COP9 signalosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Crystal structure of the human ubiquitin-like protein NEDD8 and interactions with ubiquitin pathway enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

The F-box protein Skp2 is a ubiquitylation target of a Cul1-based core ubiquitin ligase complex: evidence for a role of Cul1 in the suppression of Skp2 expression in quiescent fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Conjugation of Nedd8 to CUL1 enhances the ability of the ROC1-CUL1 complex to promote ubiquitin polymerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

The Nedd8-conjugated ROC1-CUL1 core ubiquitin ligase utilizes Nedd8 charged surface residues for efficient polyubiquitin chain assembly catalyzed by Cdc34

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

The SCF(HOS/beta-TRCP)-ROC1 E3 ubiquitin ligase utilizes two distinct domains within CUL1 for substrate targeting and ubiquitin ligation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

DEN1 is a dual function protease capable of processing the C terminus of Nedd8 and deconjugating hyper-neddylated CUL1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

COP9 signalosome subunit 3 is essential for maintenance of cell proliferation in the mouse embryonic epiblast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

The COP9 signalosome inhibits p27(kip1) degradation and impedes G1-S phase progression via deneddylation of SCF Cul1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Ubiquitin-like proteins: new wines in new bottles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Identification of a Cullin Homology Region in a Subunit of the Anaphase-Promoting Complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Mass spectrometric analysis of the anaphase-promoting complex from yeast: identification of a subunit related to cullins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

CAND1 binds to unneddylated CUL1 and regulates the formation of SCF ubiquitin E3 ligase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

CUL-4 ubiquitin ligase maintains genome stability by restraining DNA-replication licensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

The fission yeast COP9/signalosome is involved in cullin modification by ubiquitin-related Ned8p

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Fission yeast COP9/signalosome suppresses cullin activity through recruitment of the deubiquitylating enzyme Ubp12p

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

Interactions of the COP9 Signalosome with the E3 Ubiquitin Ligase SCFTIR1 in Mediating Auxin Response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207414

21 January 2018

Identifiers

DOI

10.1038/SJ.ONC.1207414

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15021886 AND SRC:MED&resulttype=core&format=json

Dimensions Publication ID

25 December 2019

1023651648

0 references

1 reference