(Q33906823)

29 July 2017

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title

Pharmacogenetics and the practice of medicine (English)

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29 July 2017

Roses AD

1

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29 July 2017

language of work or name

English

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publication date

1 June 2000

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29 July 2017

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29 July 2017

volume

405

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29 July 2017

issue

6788

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29 July 2017

page(s)

857-865

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Potassium ion channels and human disease: phenotypes to drug targets?

29 July 2017

cites work

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7 January 2021

Drug target validation and identification of secondary drug target effects using DNA microarrays

1 reference

7 January 2021

Proteomics: quantitative and physical mapping of cellular proteins

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7 January 2021

Comparative gene-expression analysis

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7 January 2021

Differential gene expression in drug metabolism and toxicology: practicalities, problems and potential

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7 January 2021

Apolipoprotein E affects the rate of Alzheimer disease expression: beta-amyloid burden is a secondary consequence dependent on APOE genotype and duration of disease

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7 January 2021

Apolipoprotein E expression by neurons surviving excitotoxic stress

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7 January 2021

Human apolipoprotein E2, E3, and E4 isoform-specific transgenic mice: human-like pattern of glial and neuronal immunoreactivity in central nervous system not observed in wild-type mice.

1 reference

7 January 2021

Regionally specific neuronal expression of human APOE gene in transgenic mice

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7 January 2021

Specific regional transcription of apolipoprotein E in human brain neurons

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7 January 2021

Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase

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7 January 2021

Orphan nuclear receptors: shifting endocrinology into reverse

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7 January 2021

Dominant negative mutations in human PPARgamma associated with severe insulin resistance, diabetes mellitus and hypertension

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7 January 2021

Apolipoprotein E alleles as risk factors in Alzheimer's disease

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7 January 2021

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

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7 January 2021

Candidate gene for the chromosome 1 familial Alzheimer's disease locus

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7 January 2021

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

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7 January 2021

Alzheimer's disease and hereditary cerebral hemorrhage with amyloidosis-Dutch type share a decrease in cerebrospinal fluid levels of amyloid beta-protein precursor

1 reference

7 January 2021

Molecular genetics of diabetes mellitus

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7 January 2021

The genetics of asthma

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7 January 2021

Genetics of complex disease: approaches, problems, and solutions

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7 January 2021

A second-generation screen of the human genome for susceptibility to insulin-dependent diabetes mellitus

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7 January 2021

Irritable bowel syndrome: disease definition and symptom description

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7 January 2021

Additional investigations fail to alter the diagnosis of irritable bowel syndrome in subjects fulfilling the Rome criteria.

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7 January 2021

Pharmacogenomics: translating functional genomics into rational therapeutics

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7 January 2021

Molecular mechanisms of genetic polymorphisms of drug metabolism

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7 January 2021

Clinical implications of antidepressant pharmacokinetics and pharmacogenetics

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7 January 2021

Desipramine pharmacokinetics in Chinese and Caucasian volunteers

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7 January 2021

Mapping of complex traits by single-nucleotide polymorphisms

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7 January 2021

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7 January 2021

Determination of ancestral alleles for human single-nucleotide polymorphisms using high-density oligonucleotide arrays

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7 January 2021

Polymorphism of the cytochrome P450 CYP2D6 gene in a European population: characterization of 48 mutations and 53 alleles, their frequencies and evolution

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7 January 2021

A 4-Mb high-density single nucleotide polymorphism-based map around human APOE

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7 January 2021

Analysis of association at single nucleotide polymorphisms in the APOE region.

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7 January 2021

Prospects for whole-genome linkage disequilibrium mapping of common disease genes

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7 January 2021

Genetic epidemiology of single-nucleotide polymorphisms.

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7 January 2021

Predicting the range of linkage disequilibrium

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7 January 2021

A microsphere-based assay for multiplexed single nucleotide polymorphism analysis using single base chain extension

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7 January 2021

Pharmacogenetics and future drug development and delivery

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7 January 2021

Broad patterns of gene expression revealed by clustering analysis of tumor and normal colon tissues probed by oligonucleotide arrays

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7 January 2021

Clinical trials in the genomic era: effects of protective genotypes on sample size and duration of trial

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7 January 2021

Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies

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7 January 2021

Making medicines safer--the need for an independent drug safety board.

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7 January 2021

Targets and systems of health care cost control

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7 January 2021

Genetic testing for BRCA1 and BRCA2: recommendations of the Stanford Program in Genomics, Ethics, and Society. Breast Cancer Working Group

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7 January 2021

Drug metabolism polymorphisms as modulators of cancer susceptibility.

1 reference

7 January 2021

Specificity, sensitivity, and predictive value of apolipoprotein-E genotyping for sporadic Alzheimer's disease

1 reference

7 January 2021

Utility of the apolipoprotein E genotype in the diagnosis of Alzheimer's disease. Alzheimer's Disease Centers Consortium on Apolipoprotein E and Alzheimer's Disease

1 reference

7 January 2021

Genetic testing for Alzheimer disease. Practical and ethical issues

1 reference

7 January 2021

Apolipoprotein E is a relevant susceptibility gene that affects the rate of expression of Alzheimer's disease

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7 January 2021

Identifiers

DOI

10.1038/35015728

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Dimensions Publication ID

29 July 2017

1045189863

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