(Q33840470)

29 July 2017

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title

Proteolysis and the cell cycle: with this RING I do thee destroy (English)

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29 July 2017

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M Tyers

1

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29 July 2017

P Jorgensen

series ordinal

2

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29 July 2017

language of work or name

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1 February 2000

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Current Opinion in Genetics & Development

29 July 2017

published in

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29 July 2017

volume

10

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29 July 2017

issue

1

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29 July 2017

page(s)

54-64

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Whose end is destruction: cell division and the anaphase-promoting complex

29 July 2017

cites work

1 reference

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7 January 2021

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7 January 2021

Combinatorial control in ubiquitin-dependent proteolysis: don't Skp the F-box hypothesis

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https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Two F-box/WD-repeat proteins Pop1 and Pop2 form hetero- and homo-complexes together with cullin-1 in the fission yeast SCF (Skp1-Cullin-1-F-box) ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

F-box/WD-repeat proteins pop1p and Sud1p/Pop2p form complexes that bind and direct the proteolysis of cdc18p

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https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Phosphorylation controls timing of Cdc6p destruction: A biochemical analysis

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

sud1( ) targets cyclin-dependent kinase-phosphorylated Cdc18 and Rum1 proteins for degradation and stops unwanted diploidization in fission yeast

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Yeast G1 cyclins are unstable in G1 phase

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

The Cdc42p effector Gic2p is targeted for ubiquitin-dependent degradation by the SCFGrr1 complex

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Feedback-regulated degradation of the transcriptional activator Met4 is triggered by the SCF(Met30 )complex

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Cdc34 and the F-box protein Met30 are required for degradation of the Cdk-inhibitory kinase Swe1.

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

The morphogenesis checkpoint in Saccharomyces cerevisiae: cell cycle control of Swe1p degradation by Hsl1p and Hsl7p

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https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Ubiquitination and degradation of the substrate recognition subunits of SCF ubiquitin-protein ligases

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Ubiquitin-dependent degradation of multiple F-box proteins by an autocatalytic mechanism

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

The abundance of cell cycle regulatory protein Cdc4p is controlled by interactions between its F box and Skp1p

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

A ubiquitin ligase complex essential for the NF-kappaB, Wnt/Wingless, and Hedgehog signaling pathways

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Interaction between ubiquitin-protein ligase SCFSKP2 and E2F-1 underlies the regulation of E2F-1 degradation

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

The murine gene p27Kip1 is haplo-insufficient for tumour suppression

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Regulation of cyclin A-Cdk2 by SCF component Skp1 and F-box protein Skp2

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Deletion of the Cul1 gene in mice causes arrest in early embryogenesis and accumulation of cyclin E

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Coupling of mitosis to the completion of S phase through Cdc34-mediated degradation of Wee1.

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Association of human SCF(SKP2) subunit p19(SKP1) with interphase centrosomes and mitotic spindle poles

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Cdc4, a protein required for the onset of S phase, serves an essential function during G(2)/M transition in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Cell cycle-regulated proteolysis of mitotic target proteins

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

A family of mammalian F-box proteins

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Identification of a family of human F-box proteins

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Identification of novel F-box proteins in Xenopus laevis

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1.

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

SGT1 encodes an essential component of the yeast kinetochore assembly pathway and a novel subunit of the SCF ubiquitin ligase complex

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

The von Hippel-Lindau tumor suppressor protein is a component of an E3 ubiquitin-protein ligase activity

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

CUL-2 is required for the G1-to-S-phase transition and mitotic chromosome condensation in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Geminin, an inhibitor of DNA replication, is degraded during mitosis

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

APC(Cdc20) promotes exit from mitosis by destroying the anaphase inhibitor Pds1 and cyclin Clb5.

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

The regulation of Cdc20 proteolysis reveals a role for APC components Cdc23 and Cdc27 during S phase and early mitosis

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Polo-like kinases: positive regulators of cell division from start to finish.

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

PKA and MPF-activated polo-like kinase regulate anaphase-promoting complex activity and mitosis progression.

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Phosphorylation of the cyclosome is required for its stimulation by Fizzy/cdc20.

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Fission yeast cut mutations revisited: control of anaphase

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Chromosome Separation and Exit from Mitosis in Budding Yeast: Dependence on Growth Revealed by cAMP-Mediated Inhibition

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

The ties that bind: localization of the sister-chromatid cohesin complex on yeast chromosomes

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Cut1 is loaded onto the spindle by binding to Cut2 and promotes anaphase spindle movement upon Cut2 proteolysis.

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Sister chromatid separation and chromosome re-duplication are regulated by different mechanisms in response to spindle damage

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Regulation of the APC and the exit from mitosis

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Inhibitory phosphorylation of the APC regulator Hct1 is controlled by the kinase Cdc28 and the phosphatase Cdc14.

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

The phosphatase Cdc14 triggers mitotic exit by reversal of Cdk-dependent phosphorylation

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Cfi1 prevents premature exit from mitosis by anchoring Cdc14 phosphatase in the nucleolus

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Net1, a Sir2-associated nucleolar protein required for rDNA silencing and nucleolar integrity

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

The Polo-like kinase Cdc5p and the WD-repeat protein Cdc20p/fizzy are regulators and substrates of the anaphase promoting complex in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Controlling septation in fission yeast: finding the middle, and timing it right

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Morphogenesis beyond cytokinetic arrest in Saccharomyces cerevisiae.

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Byr4 and Cdc16 form a two-component GTPase-activating protein for the Spg1 GTPase that controls septation in fission yeast

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Bifurcation of the mitotic checkpoint pathway in budding yeast

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

A Bub2p-dependent spindle checkpoint pathway regulates the Dbf2p kinase in budding yeast.

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Budding yeast Bub2 is localized at spindle pole bodies and activates the mitotic checkpoint via a different pathway from Mad2

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Pds1 and Esp1 control both anaphase and mitotic exit in normal cells and after DNA damage.

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Pds1p of budding yeast has dual roles: inhibition of anaphase initiation and regulation of mitotic exit

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

A late mitotic regulatory network controlling cyclin destruction in Saccharomyces cerevisiae.

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

CDC5 and CKII Control Adaptation to the Yeast DNA Damage Checkpoint

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase to anaphase transition in budding yeast

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Cdc20 is essential for the cyclosome-mediated proteolysis of both Pds1 and Clb2 during M phase in budding yeast.

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

Deregulated cyclin E induces chromosome instability

1 reference

https://api.crossref.org/works/10.1016/S0959-437X(99)50049-0

7 January 2021

10.1016/S0959-437X(99)00049-0

Identifiers

DOI

1 reference

29 July 2017

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