(Q33358684)

26 July 2017

title

E2F and p53 induce apoptosis independently during Drosophila development but intersect in the context of DNA damage (English)

1 reference

26 July 2017

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Retinoblastoma-family protein Dmel_CG7413

1 reference

DP transcription factor Dmel_CG4654

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Head involution defective Dmel_CG5123

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author name string

Nam-Sung Moon

1

1 reference

26 July 2017

Luisa Di Stefano

2

1 reference

26 July 2017

Erick J Morris

3

1 reference

26 July 2017

Reena Patel

4

1 reference

26 July 2017

Kristin White

5

1 reference

26 July 2017

Nicholas J Dyson

6

1 reference

26 July 2017

publication date

8 August 2008

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26 July 2017

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26 July 2017

volume

4

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26 July 2017

issue

8

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26 July 2017

page(s)

e1000153

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Creative Commons Attribution 4.0 International

26 July 2017

copyright license

start time

8 August 2008

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2491587/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Epigenetic blocking of an enhancer region controls irradiation-induced proapoptotic gene expression in Drosophila embryos

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Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

21 June 2018

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Functional identification of Api5 as a suppressor of E2F-dependent apoptosis in vivo

21 June 2018

1 reference

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Inactivation of the p53 pathway in retinoblastoma.

21 June 2018

1 reference

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A gradient of epidermal growth factor receptor signaling determines the sensitivity of rbf1 mutant cells to E2F-dependent apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2491587

E2F1-induced apoptosis: turning killers into therapeutics

21 June 2018

1 reference

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Inhibitors of histone deacetylases target the Rb-E2F1 pathway for apoptosis induction through activation of proapoptotic protein Bim.

21 June 2018

1 reference

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Drosophila E2F1 has context-specific pro- and antiapoptotic properties during development

21 June 2018

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The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes

21 June 2018

1 reference

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Cell type-specific effects of Rb deletion in the murine retina.

21 June 2018

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Drosophila melanogaster MNK/Chk2 and p53 regulate multiple DNA repair and apoptotic pathways following DNA damage

21 June 2018

1 reference

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Up-regulation of Bcl-2 homology 3 (BH3)-only proteins by E2F1 mediates apoptosis

21 June 2018

1 reference

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The RB and p53 pathways in cancer

21 June 2018

1 reference

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E2F1 induces phosphorylation of p53 that is coincident with p53 accumulation and apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2491587

Targeted mutagenesis by homologous recombination in D. melanogaster

21 June 2018

1 reference

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Novel function of the cyclin A binding site of E2F in regulating p53-induced apoptosis in response to DNA damage

21 June 2018

1 reference

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PUMA, a novel proapoptotic gene, is induced by p53

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2491587

PUMA induces the rapid apoptosis of colorectal cancer cells

21 June 2018

1 reference

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21 June 2018

E2F-1 induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2491587

Role of the p53-homologue p73 in E2F1-induced apoptosis

21 June 2018

1 reference

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Role for the p53 homologue p73 in E2F-1-induced apoptosis

21 June 2018

1 reference

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Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

21 June 2018

1 reference

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Drosophila p53 binds a damage response element at the reaper locus

21 June 2018

1 reference

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Drosophila p53 is a structural and functional homolog of the tumor suppressor p53.

21 June 2018

1 reference

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Apoptotic and growth-promoting activity of E2F modulated by MDM2

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2491587

Functions of the retinoblastoma protein

21 June 2018

1 reference

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The role of RBF in the introduction of G1 regulation during Drosophila embryogenesis

21 June 2018

1 reference

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p14ARF links the tumour suppressors RB and p53.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2491587

Mutations in Drosophila DP and E2F distinguish G1–S progression from an associated transcriptional program

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2491587

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2491587

p53 and E2F-1 cooperate to mediate apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2491587

E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2491587

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2491587

A common E2F-1 and p73 pathway mediates cell death induced by TCR activation.

21 June 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1000153

Differential regulation of E2F1 apoptotic target genes in response to DNA damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1000153

Ectopic E2F expression induces S phase and apoptosis in Drosophila imaginal discs

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1000153

Cell-specific effects of RB or RB/p107 loss on retinal development implicate an intrinsically death-resistant cell-of-origin in retinoblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1000153

Inactivation of the retinoblastoma tumor suppressor induces apoptosis protease-activating factor-1 dependent and independent apoptotic pathways during embryogenesis.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2491587

Suppression of the p53- or pRB-mediated G1 checkpoint is required for E2F-induced S-phase entry

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18688282

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PGEN.1000153

1 reference

26 July 2017

1 reference

26 July 2017

1 reference