(Q30319332)

17 June 2017

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title

Glutaminyl cyclases from animals and plants: a case of functionally convergent protein evolution (English)

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17 June 2017

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Stephan Schilling

1

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17 June 2017

Claus Wasternack

series ordinal

2

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17 June 2017

Hans-Ulrich Demuth

series ordinal

3

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17 June 2017

publication date

1 August 2008

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17 June 2017

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17 June 2017

volume

389

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17 June 2017

issue

8

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17 June 2017

page(s)

983-991

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Crystallization and preliminary X-ray diffraction studies of the glutaminyl cyclase from Carica papaya latex

17 June 2017

cites work

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Detection of three wound-induced proteins in papaya latex

21 January 2018

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The role of pyrrolidone carboxylic acid in the initiation of immunoglobulin peptide chains.

21 January 2018

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Evidence for essential histidines in human pituitary glutaminyl cyclase

21 January 2018

1 reference

Human glutaminyl cyclase and bacterial zinc aminopeptidase share a common fold and active site

21 January 2018

1 reference

Partial amino-acid sequence of the precursor of an immunoglobulin light chain containing NH2-terminal pyroglutamic acid

21 January 2018

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Inhibition of glutaminyl cyclase alters pyroglutamate formation in mammalian cells

21 January 2018

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Carica papaya glutamine cyclotransferase belongs to a novel plant enzyme subfamily: cloning and characterization of the recombinant enzyme.

21 January 2018

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Revisiting the enzymes stored in the laticifers of Carica papaya in the context of their possible participation in the plant defence mechanism

21 January 2018

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Identification of a mammalian glutaminyl cyclase converting glutaminyl into pyroglutamyl peptides

21 January 2018

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Formation of N-pyroglutamyl peptides from N-Glu and N-Gln precursors in Aplysia neurons

21 January 2018

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A newly formed amyloidogenic fragment due to a stop codon mutation causes familial British dementia

21 January 2018

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Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer beta-amyloid peptides

21 January 2018

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gamma-Secretase cleavage site specificity differs for intracellular and secretory amyloid beta.

21 January 2018

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Papaya glutamine cyclotransferase shows a singular five-fold beta-propeller architecture that suggests a novel reaction mechanism.

21 January 2018

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High sensitivity analysis of amyloid-beta peptide composition in amyloid deposits from human and PS2APP mouse brain

21 January 2018

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Alzheimer's disease: the amyloid cascade hypothesis

21 January 2018

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Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides.

21 January 2018

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The A beta 3-pyroglutamyl and 11-pyroglutamyl peptides found in senile plaque have greater beta-sheet forming and aggregation propensities in vitro than full-length A beta.

21 January 2018

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Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation

21 January 2018

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Cloning, expression, characterization, and crystallization of a glutaminyl cyclase from human bone marrow: a single zinc metalloenzyme

21 January 2018

1 reference

Isolation, Chemical Characterization, and Quantitation of Aβ 3-Pyroglutamyl Peptide from Neuritic Plaques and Vascular Amyloid Deposits

21 January 2018

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Contribution of active-site residues to the function of onconase, a ribonuclease with antitumoral activity

21 January 2018

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Analysis of gene families encoding acidic and basic beta-1,3-glucanases of tobacco

21 January 2018

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Metalloaminopeptidases: common functional themes in disparate structural surroundings

21 January 2018

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A new class of tobacco chitinases homologous to bacterial exo-chitinases displays antifungal activity

21 January 2018

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Amino-terminally truncated Abeta peptide species are the main component of cotton wool plaques

21 January 2018

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Pyroglutamyl peptidase type I from Trypanosoma brucei: a new virulence factor from African trypanosomes that de-blocks regulatory peptides in the plasma of infected hosts

21 January 2018

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Neuroregulation of ProTRH biosynthesis and processing

21 January 2018

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Regulation of prohormone convertases in hypothalamic neurons: implications for prothyrotropin-releasing hormone and proopiomelanocortin

21 January 2018

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The biology of pro-thyrotropin-releasing hormone-derived peptides

21 January 2018

1 reference

21 January 2018

Fibronectin at a glance

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Methyl salicylate is a critical mobile signal for plant systemic acquired resistance

21 January 2018

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The biosynthesis and processing of neuropeptides: lessons from prothyrotropin releasing hormone (proTRH).

21 January 2018

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beta-amyloid is different in normal aging and in Alzheimer disease.

21 January 2018

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Association of a presenilin 1 S170F mutation with a novel Alzheimer disease molecular phenotype

21 January 2018

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Primary structure and functional expression of a glutaminyl cyclase

21 January 2018

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The biology of cholecystokinin and gastrin peptides

21 January 2018

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Morphological and biochemical analyses of amyloid plaque core proteins purified from Alzheimer disease brain tissue.

21 January 2018

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Heterogeneity of water‐soluble amyloid β‐peptide in Alzheimer's disease and Down's syndrome brains

21 January 2018

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Presenilin-1 mutations in Alzheimer's disease.

21 January 2018

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Alzheimer’s Disease as Proteolytic Disorders: Anabolism and Catabolism of β-Amyloid

21 January 2018

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Dominant and differential deposition of distinct beta-amyloid peptide species, A beta N3(pE), in senile plaques.

21 January 2018

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Heterologous expression and characterization of human glutaminyl cyclase: evidence for a disulfide bond with importance for catalytic activity

21 January 2018

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Substrate specificity of glutaminyl cyclases from plants and animals

21 January 2018

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Identification of human glutaminyl cyclase as a metalloenzyme. Potent inhibition by imidazole derivatives and heterocyclic chelators

21 January 2018

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Glutaminyl cyclases unfold glutamyl cyclase activity under mild acid conditions

21 January 2018

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Isolation and characterization of glutaminyl cyclases from Drosophila: evidence for enzyme forms with different subcellular localization

21 January 2018

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Isolation and characterization of the glutaminyl cyclases from Solanum tuberosum and Arabidopsis thaliana: implications for physiological functions

21 January 2018

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Alzheimer's disease is a synaptic failure

21 January 2018

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Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics

21 January 2018

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Review article: gastrin and colorectal cancer

21 January 2018

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Molecular cloning, sequence analysis and expression of human pituitary glutaminyl cyclase

21 January 2018

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Evidence for tissue-specific forms of glutaminyl cyclase

21 January 2018

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Familial Danish dementia: co-existence of Danish and Alzheimer amyloid subunits (ADan AND A{beta}) in the absence of compact plaques

21 January 2018

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Glutamic acid as a precursor to N-terminal pyroglutamic acid in mouse plasmacytoma protein (protein synthesis-initiation-immunoglobulins-pyrrolidone carboxylic acid).

21 January 2018

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Acquired resistance in Arabidopsis

21 January 2018

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Functional comparison of two human monocyte chemotactic protein-2 isoforms, role of the amino-terminal pyroglutamic acid and processing by CD26/dipeptidyl peptidase IV.

21 January 2018

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Significance of inducible defense-related proteins in infected plants.

21 January 2018

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Gastrin: an analytical review

21 January 2018

1 reference

A stop-codon mutation in the BRI gene associated with familial British dementia

21 January 2018

1 reference

Crystal structure of papaya glutaminyl cyclase, an archetype for plant and bacterial glutaminyl cyclases

21 January 2018

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Papaya glutamine cyclase, a plant enzyme highly resistant to proteolysis, adopts an all-beta conformation

21 January 2018

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Enzymatic Cyclization of L-Glutamine and L-Glutaminyl Peptides

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1515/BC.2008.111

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17 June 2017

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