(Q29817044)

English

Immune deficiency Dmel_CG5576

Protein found in Drosophila melanogaster

imd-PB
immune deficient
immunodeficiency
CG5576-PA
imd
CG5576-PB
imd-PA
CG5576 gene product from transcript CG5576-RB
immune deficiency

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Statements

1 reference

25 May 2022

Death-like domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q7K4Z4

Death domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Drosophila melanogaster

1 reference

25 May 2022

1 reference

25 May 2022

determination method or standard

IPI

1 reference

retrieved

8 April 2019

stated in

The Drosophila immune defense against gram-negative infection requires the death protein dFADD.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K4Z4

determination method or standard

IPI

biological process

positive regulation of defense response to virus by host

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

A Novel System for the Launch of Alphavirus RNA Synthesis Reveals a Role for the Imd Pathway in Arthropod Antiviral Response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K4Z4

determination method or standard

IMP

defense response

determination method or standard

TAS

1 reference

retrieved

7 November 2018

stated in

The antimicrobial host defense of Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7K4Z4&geneProductId=UniProtKB:Q7K4Z4

determination method or standard

TAS

immune response

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

Drosophila Thor participates in host immune defense and connects a translational regulator with innate immunity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K4Z4

determination method or standard

IMP

humoral immune response

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

Characterization of an immunodeficiency mutant in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K4Z4

determination method or standard

IMP

positive regulation of antibacterial peptide biosynthetic process

determination method or standard

IMP

positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

Iap2 is required for a sustained response in the Drosophila Imd pathway.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K4Z4

determination method or standard

IMP

signal transduction

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K4Z4

determination method or standard

IEA

nervous system development

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

RNA interference screen to identify genes required for Drosophila embryonic nervous system development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K4Z4

determination method or standard

IMP

response to bacterium

determination method or standard

NAS

1 reference

retrieved

8 April 2019

stated in

Flies kNOw how to signal

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K4Z4

determination method or standard

NAS

antimicrobial humoral response

determination method or standard

IGI

IMP

intracellular signal transduction

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

Drosophila: the genetics of innate immune recognition and response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K4Z4

determination method or standard

TAS

defense response to bacterium

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

The evolution and genetics of innate immunity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K4Z4

determination method or standard

TAS

innate immune response

determination method or standard

NAS

1 reference

retrieved

16 July 2018

stated in

The complexity of genetic variation in a simple immune system

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7K4Z4&geneProductId=UniProtKB:Q7K4Z4

determination method or standard

NAS

positive regulation of innate immune response

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

Akirins are highly conserved nuclear proteins required for NF-kappaB-dependent gene expression in drosophila and mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K4Z4

determination method or standard

IMP

peptidoglycan recognition protein signaling pathway

determination method or standard

IMP

3 references

retrieved

8 April 2019

stated in

Differential display of peptides induced during the immune response of Drosophila : A matrix-assisted laser desorption ionization time-of-flight mass spectrometry study

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K4Z4

determination method or standard

IMP

retrieved

8 April 2019

stated in

The Drosophila caspase Dredd is required to resist gram-negative bacterial infection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K4Z4

determination method or standard

IMP

retrieved

8 April 2019

stated in

Two roles for the Drosophila IKK complex in the activation of Relish and the induction of antimicrobial peptide genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K4Z4

determination method or standard

IMP

immune system process

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K4Z4

determination method or standard

IEA

positive regulation of antibacterial peptide production

determination method or standard

IGI

1 reference

retrieved

8 April 2019

stated in

The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K4Z4

determination method or standard

IGI

antimicrobial humoral response

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

Inhibitor of apoptosis 2 and TAK1-binding protein are components of the Drosophila Imd pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K4Z4

determination method or standard

IMP

innate immune response

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7K4Z4

determination method or standard

1 reference

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q7K4Z4

Identifiers

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

1 reference

(Q29817044)

Immune deficiency Dmel_CG5576

Statements

Identifiers

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