(Q28609153)

3 February 2017

title

The cytokine-activated tyrosine kinase JAK2 activates Raf-1 in a p21ras-dependent manner (English)

1 reference

3 February 2017

K. Xia

1

1 reference

3 February 2017

N. K. Mukhopadhyay

2

1 reference

3 February 2017

R. C. Inhorn

3

1 reference

3 February 2017

D. L. Barber

4

1 reference

3 February 2017

P. E. Rose

5

1 reference

3 February 2017

R. S. Lee

6

1 reference

3 February 2017

R. P. Narsimhan

7

1 reference

3 February 2017

A. D. D'Andrea

8

1 reference

3 February 2017

J. D. Griffin

9

1 reference

3 February 2017

T. M. Roberts

10

1 reference

3 February 2017

language of work or name

English

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publication date

15 October 1996

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Proceedings of the National Academy of Sciences of the United States of America

3 February 2017

published in

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3 February 2017

volume

93

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3 February 2017

issue

21

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3 February 2017

page(s)

11681–11686

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JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

3 February 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38118

The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38118

Identification of the sites in MAP kinase kinase-1 phosphorylated by p74raf-1

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38118

Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38118

Interaction of the protein kinase Raf-1 with 14-3-3 proteins

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38118

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38118

Requirement of serine phosphorylation for formation of STAT-promoter complexes

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38118

A Single Phosphotyrosine Residue of Stat91 Required for Gene Activation by Interferon-γ

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38118

Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38118

A protein tyrosine kinase in the interferon alpha/beta signaling pathway

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38118

Activation of transcription by IFN-gamma: tyrosine phosphorylation of a 91-kD DNA binding protein

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38118

Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38118

Activation of Raf as a result of recruitment to the plasma membrane

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38118

JAK2, Ras, and Raf are required for activation of extracellular signal-regulated kinase/mitogen-activated protein kinase by growth hormone

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38118

Raf-1 and p21v-ras cooperate in the activation of mitogen-activated protein kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38118

Activation of MEK family kinases requires phosphorylation of two conserved Ser/Thr residues.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38118

Jaks and Stats in signaling by the cytokine receptor superfamily

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38118

Critical Tyrosine Residues Regulate the Enzymatic and Biological Activity of Raf-1 Kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38118

ISGF3, the transcriptional activator induced by interferon alpha, consists of multiple interacting polypeptide chains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38118

Interleukin 2 induces tyrosine phosphorylation and activation of p72-74 Raf-1 kinase in a T-cell line

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38118

Interleukin-2-triggered Raf-1 expression, phosphorylation, and associated kinase activity increase through G1 and S in CD3-stimulated primary human T cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38118

Both p21ras and pp60v-src are required, but neither alone is sufficient, to activate the Raf-1 kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38118

Erythropoietin and interleukin-2 activate distinct JAK kinase family members

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38118

Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-gamma signal transduction pathway

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38118

Polypeptide signalling to the nucleus through tyrosine phosphorylation of Jak and Stat proteins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38118

Activation of the erythropoietin receptor by the Friend spleen focus-forming virus gp55 glycoprotein induces constitutive protein tyrosine phosphorylation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38118

3 June 2018

A signal chain of events

1 reference

12 December 2020

1 reference

12 December 2020

Requirement for MAP kinase (ERK2) activity in interferon alpha- and interferon beta-stimulated gene expression through STAT proteins

1 reference

12 December 2020

Erythropoietin induces Raf-1 activation and Raf-1 is required for erythropoietin-mediated proliferation

1 reference

12 December 2020

Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.93.21.11681

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