(Q27933382)

1 December 2016

title

Manipulation of a nuclear NAD salvage pathway delays aging without altering steady-state NAD levels (English)

1 reference

PubMed

Nicotinamide-nucleotide adenylyltransferase NMA2 YGR010W

1 December 2016

main subject

1 reference

Nicotinate phosphoribosyltransferase YOR209C

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

David A Sinclair

9

0 references

Jeffrey I. Gordon

8

Jeffrey I Gordon

0 references

Rozalyn Anderson

1

Rozalyn M Anderson

0 references

Oliver Medvedik

4

Oliver Medvedik

0 references

Kevin J Bitterman

2

Kevin J Bitterman

0 references

author name string

Jason G Wood

3

0 references

Haim Cohen

5

0 references

Stephen S Lin

6

0 references

Jill K Manchester

Journal of Biological Chemistry

7

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language of work or name

English

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publication date

24 May 2002

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published in

1 reference

PubMed

Caloric restriction and aging: an update

1 December 2016

volume

277

0 references

issue

21

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page(s)

18881-90

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cites work

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Mechanisms of life span determination in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

A conserved regulatory system for aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Genetic pathways that regulate ageing in model organisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Evolution of senescence: late survival sacrificed for reproduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Accelerated Aging and Nucleolar Fragmentation in Yeast sgs1 Mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Life span of individual yeast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Daughter cells of Saccharomyces cerevisiae from old mothers display a reduced life span

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Enhanced gluconeogenesis and increased energy storage as hallmarks of aging in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Mutations in signal transduction proteins increase stress resistance and longevity in yeast, nematodes, fruit flies, and mammalian neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

21 January 2018

New clues to old yeast

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Extrachromosomal rDNA circles--a cause of aging in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Effects of mutations in DNA repair genes on formation of ribosomal DNA circles and life span in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Elimination of replication block protein Fob1 extends the life span of yeast mother cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

A phylogenetically conserved NAD -dependent protein deacetylase activity in the Sir2 protein family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Net1, a Sir2-associated nucleolar protein required for rDNA silencing and nucleolar integrity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Net1 stimulates RNA polymerase I transcription and regulates nucleolar structure independently of controlling mitotic exit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Coupling of histone deacetylation to NAD breakdown by the yeast silencing protein Sir2: Evidence for acetyl transfer from substrate to an NAD breakdown product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

A genetic screen for ribosomal DNA silencing defects identifies multiple DNA replication and chromatin-modulating factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Cloning and nucleic acid sequence of the Salmonella typhimurium pncB gene and structure of nicotinate phosphoribosyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Energy coupling through molecular discrimination: nicotinate phosphoribosyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Identification and characterization of YLR328W, the Saccharomyces cerevisiae structural gene encoding NMN adenylyltransferase. Expression and characterization of the recombinant enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Structural gene for NAD synthetase in Salmonella typhimurium

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

An unusual form of transcriptional silencing in yeast ribosomal DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Interactions between three common subunits of yeast RNA polymerases I and III.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

A cDNA encoding a human CCAAT-binding protein cloned by functional complementation in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

A new efficient gene disruption cassette for repeated use in budding yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

A novel multi-purpose cassette for repeated integrative epitope tagging of genes in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Genetic analysis of aging in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Identification, characterization, and crystal structure of Bacillus subtilis nicotinic acid mononucleotide adenylyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Structure of nicotinamide mononucleotide adenylyltransferase: a key enzyme in NAD( ) biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Insights into ligand binding and catalysis of a central step in NAD synthesis: structures of Methanobacterium thermoautotrophicum NMN adenylyltransferase complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Genomewide studies of histone deacetylase function in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Identification of a small molecule inhibitor of Sir2p

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

A cytosolic NAD-dependent deacetylase, Hst2p, can modulate nucleolar and telomeric silencing in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Characterization of a human gene with sequence homology to Saccharomyces cerevisiae SIR2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

The Sir2 protein family: A novel deacetylase for gene silencing and more

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Conversion of a cosubstrate to an inhibitor: phosphorylation mutants of nicotinic acid phosphoribosyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

Aging, chromatin, and food restriction--connecting the dots

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111773200

21 January 2018

Identifiers

DOI

10.1074/JBC.M111773200

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017