(Q27860923)

7 January 2021

Insulin resistance and atherosclerosis

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7 January 2021

Inflammation, stress, and diabetes

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7 January 2021

Mediators of Inflammation

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7 January 2021

Innate immunity: an overview

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7 January 2021

Population Biology, Evolution, and Infectious Disease: Convergence and Synthesis

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7 January 2021

Homology between the mammalian liver and the Drosophila fat body

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7 January 2021

The immune response of Drosophila melanogaster

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7 January 2021

Function of GATA transcription factors in preadipocyte-adipocyte transition

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7 January 2021

Programmed autophagy in the Drosophila fat body is induced by ecdysone through regulation of the PI3K pathway

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7 January 2021

Activation of Toll-like receptor 4 is associated with insulin resistance in adipocytes

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7 January 2021

TLR4 links innate immunity and fatty acid-induced insulin resistance

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7 January 2021

Inflammation and insulin resistance

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7 January 2021

Akt and FOXO dysregulation contribute to infection-induced wasting in Drosophila

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7 January 2021

Impact of obesity on treatment of chronic hepatitis C.

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7 January 2021

Inflammation: the link between insulin resistance, obesity and diabetes

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7 January 2021

Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance

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7 January 2021

Protection from obesity-induced insulin resistance in mice lacking TNF-α function

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7 January 2021

Targeted disruption of the tumor necrosis factor-alpha gene: metabolic consequences in obese and nonobese mice

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7 January 2021

Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance

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7 January 2021

The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase

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7 January 2021

The expression of TNF alpha by human muscle. Relationship to insulin resistance

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7 January 2021

Influence of TNF-alpha and IL-6 infusions on insulin sensitivity and expression of IL-18 in humans

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7 January 2021

Effects of an engineered human anti-TNF-alpha antibody (CDP571) on insulin sensitivity and glycemic control in patients with NIDDM.

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7 January 2021

Effects of infliximab treatment on insulin resistance in patients with rheumatoid arthritis and ankylosing spondylitis

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7 January 2021

Obesity is associated with macrophage accumulation in adipose tissue

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7 January 2021

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

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7 January 2021

Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans

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7 January 2021

IKK-beta links inflammation to obesity-induced insulin resistance

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7 January 2021

Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis

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7 January 2021

Macrophage insulin receptor deficiency increases ER stress-induced apoptosis and necrotic core formation in advanced atherosclerotic lesions.

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7 January 2021

Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle

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7 January 2021

Nuclear receptors and lipid physiology: opening the X-files

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7 January 2021

Combinatorial roles of nuclear receptors in inflammation and immunity

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7 January 2021

Minireview: lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors

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7 January 2021

Reciprocal regulation of inflammation and lipid metabolism by liver X receptors

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7 January 2021

Crosstalk between LXR and Toll-like Receptor Signaling Mediates Bacterial and Viral Antagonism of Cholesterol Metabolism

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7 January 2021

The lipopolysaccharide-activated toll-like receptor (TLR)-4 induces synthesis of the closely related receptor TLR-2 in adipocytes

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7 January 2021

Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network

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7 January 2021

Molecular determinants of crosstalk between nuclear receptors and toll-like receptors.

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7 January 2021

Lack of macrophage fatty-acid-binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis

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7 January 2021

PPARgamma : a nuclear regulator of metabolism, differentiation, and cell growth

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7 January 2021

Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein

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7 January 2021

Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes

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7 January 2021

A genetic variant at the fatty acid-binding protein aP2 locus reduces the risk for hypertriglyceridemia, type 2 diabetes, and cardiovascular disease

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7 January 2021

The adipocyte fatty acid-binding protein aP2 is required in allergic airway inflammation

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7 January 2021

Fatty acid binding proteins--the evolutionary crossroads of inflammatory and metabolic responses.

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7 January 2021

Critical nodes in signalling pathways: insights into insulin action

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7 January 2021

IRS proteins and the common path to diabetes

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7 January 2021

IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance

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7 January 2021

The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)

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7 January 2021

A molecular basis for insulin resistance. Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphory

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7 January 2021

SOCS-3 inhibits insulin signaling and is up-regulated in response to tumor necrosis factor-alpha in the adipose tissue of obese mice

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7 January 2021

SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2

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7 January 2021

Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3.

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7 January 2021

Serine phosphorylation of insulin receptor substrate 1 by inhibitor kappa B kinase complex.

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7 January 2021

Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade

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7 January 2021

Ser/Thr phosphorylation of IRS proteins: a molecular basis for insulin resistance

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7 January 2021

Signal transduction by tumor necrosis factor and its relatives

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7 January 2021

A central role for JNK in obesity and insulin resistance

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7 January 2021

Western diet modulates insulin signaling, c-Jun N-terminal kinase activity, and insulin receptor substrate-1ser307 phosphorylation in a tissue-specific fashion

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7 January 2021

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

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7 January 2021

Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance

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7 January 2021

Requirement of JNK2 for scavenger receptor A-mediated foam cell formation in atherogenesis

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7 January 2021

Possible novel therapy for diabetes with cell-permeable JNK-inhibitory peptide

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7 January 2021

Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta

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7 January 2021

Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes

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7 January 2021

Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB

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7 January 2021

PKC-theta knockout mice are protected from fat-induced insulin resistance

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7 January 2021

Free fatty acids produce insulin resistance and activate the proinflammatory nuclear factor-kappaB pathway in rat liver

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7 January 2021

NF-kappaB is required for UV-induced JNK activation via induction of PKCdelta

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7 January 2021

Endoplasmic reticulum stress signaling in disease

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7 January 2021

The mammalian unfolded protein response

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7 January 2021

Perk is essential for translational regulation and cell survival during the unfolded protein response

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7 January 2021

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

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7 January 2021

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

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7 January 2021

Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2

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7 January 2021

Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression

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7 January 2021

The endoplasmic reticulum chaperone improves insulin resistance in type 2 diabetes.

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7 January 2021

Involvement of endoplasmic reticulum stress in insulin resistance and diabetes

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7 January 2021

Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes

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7 January 2021

Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response

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7 January 2021

Coordination of ER and oxidative stress signaling: the PERK/Nrf2 signaling pathway

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7 January 2021

Tumor necrosis factor alpha (TNFalpha) induces the unfolded protein response (UPR) in a reactive oxygen species (ROS)-dependent fashion, and the UPR counteracts ROS accumulation by TNFalpha

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7 January 2021

Increased oxidative stress in obesity and its impact on metabolic syndrome

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7 January 2021

The hyperglycemia-induced inflammatory response in adipocytes: the role of reactive oxygen species

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7 January 2021

Reactive oxygen species have a causal role in multiple forms of insulin resistance

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7 January 2021

Biochemistry and molecular cell biology of diabetic complications

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7 January 2021

Mitochondrial dysfunction and type 2 diabetes

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7 January 2021

Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease – is this type 3 diabetes?

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7 January 2021

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

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7 January 2021

Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators

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7 January 2021

Aspirin inhibits serine phosphorylation of insulin receptor substrate 1 in tumor necrosis factor-treated cells through targeting multiple serine kinases

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7 January 2021

The gene MAPK8IP1, encoding islet-brain-1, is a candidate for type 2 diabetes

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7 January 2021

Peroxisome proliferator-activated receptors: from genes to physiology

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7 January 2021

Functional delivery of a cytosolic tRNA into mutant mitochondria of human cells

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7 January 2021