(Q27552551)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P40318

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Endoplasmic Reticular Retrotranslocon

1 reference

Transporter Classification Database ID

3.A.16.1.2

hierarchical database ID heuristic

2 October 2019

based on heuristic

Zinc finger, RING-CH-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40318

1 reference

14 February 2019

ubiquitin-protein transferase activity

1 reference

14 February 2019

A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Matalpha2 repressor degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40318

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40318

1 reference

14 February 2019

protein binding

5 references

14 February 2019

Membrane-bound Ubx2 recruits Cdc48 to ubiquitin ligases and their substrates to ensure efficient ER-associated protein degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40318

14 February 2019

Ubx2 links the Cdc48 complex to ER-associated protein degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40318

14 February 2019

Cadmium-mediated rescue from ER-associated degradation induces expression of its exporter

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40318

14 February 2019

Dissecting the ER-associated degradation of a misfolded polytopic membrane protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40318

14 February 2019

Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40318

transferase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40318

1 reference

14 February 2019

ubiquitin protein ligase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40318

1 reference

14 February 2019

integral component of endoplasmic reticulum membrane

1 reference

27 March 2018

A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Matalpha2 repressor degradation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40318&geneProductId=UniProtKB:P40318

nuclear envelope

1 reference

14 February 2019

A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Matalpha2 repressor degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40318

Doa10p ubiquitin ligase complex

1 reference

14 February 2019

Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40318

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40318

1 reference

14 February 2019

endoplasmic reticulum membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40318

1 reference

14 February 2019

endoplasmic reticulum

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40318&geneProductId=UniProtKB:P40318

1 reference

7 November 2018

integral component of endoplasmic reticulum membrane

IBA

integral component of membrane

Phylogenetic classification of transporters and other membrane proteins from Saccharomyces cerevisiae

3 references

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40318&geneProductId=UniProtKB:P40318

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40318&geneProductId=UniProtKB:P40318

14 January 2019

14 January 2019

Membrane topology of the yeast endoplasmic reticulum-localized ubiquitin ligase Doa10 and comparison with its human ortholog TEB4 (MARCH-VI)

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40318&geneProductId=UniProtKB:P40318

ubiquitin-dependent ERAD pathway

biological process

2 references

27 March 2018

A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Matalpha2 repressor degradation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40318&geneProductId=UniProtKB:P40318

27 March 2018

Distinct machinery is required in Saccharomyces cerevisiae for the endoplasmic reticulum-associated degradation of a multispanning membrane protein and a soluble luminal protein

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40318&geneProductId=UniProtKB:P40318

protein ubiquitination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40318

1 reference

14 February 2019

ubiquitin-dependent ERAD pathway

Distinct machinery is required in Saccharomyces cerevisiae for the endoplasmic reticulum-associated degradation of a multispanning membrane protein and a soluble luminal protein

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40318

14 February 2019

A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Matalpha2 repressor degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40318

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40318

Zinc finger, RING-CH-type

IBA

has part(s)

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P40318

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

Transporter Classification Database ID

1 reference

20 March 2022

3.A.16.1.2

2 references

Transporter Classification database

13 March 2020

Transporter Classification database