(Q27313416)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25232726 AND SRC:MED&resulttype=core&format=json

16 February 2020

title

Interplay of dFOXO and two ETS-family transcription factors determines lifespan in Drosophila melanogaster (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25232726 AND SRC:MED&resulttype=core&format=json

Forkhead box, sub-group O Dmel_CG3143

16 February 2020

main subject

Drosophila melanogaster

0 references

1 reference

GOA release 2020-03-11

Pointed Dmel_CG17077

1 reference

Anterior open Dmel_CG3166

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25232726 AND SRC:MED&resulttype=core&format=json

16 February 2020

Nazif Alic

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25232726 AND SRC:MED&resulttype=core&format=json

16 February 2020

Irene Papatheodorou

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25232726 AND SRC:MED&resulttype=core&format=json

16 February 2020

Dan Andrews

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25232726 AND SRC:MED&resulttype=core&format=json

16 February 2020

author name string

Maria E Giannakou

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25232726 AND SRC:MED&resulttype=core&format=json

16 February 2020

Matthew P Hoddinott

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25232726 AND SRC:MED&resulttype=core&format=json

16 February 2020

Ekin Bolukbasi

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25232726 AND SRC:MED&resulttype=core&format=json

16 February 2020

language of work or name

English

0 references

publication date

18 September 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25232726 AND SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25232726 AND SRC:MED&resulttype=core&format=json

16 February 2020

volume

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25232726 AND SRC:MED&resulttype=core&format=json

16 February 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25232726 AND SRC:MED&resulttype=core&format=json

16 February 2020

page(s)

e1004619

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25232726 AND SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

16 February 2020

copyright license

start time

18 September 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

on focus list of Wikimedia project

ScienceSource

0 references

cites work

Hundreds of variants clustered in genomic loci and biological pathways affect human height

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Cell signaling by receptor tyrosine kinases

21 March 2017

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21 March 2017

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Association of FOXO3A variation with human longevity confirmed in German centenarians

21 March 2017

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FOXO3A genotype is strongly associated with human longevity

21 March 2017

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Comparing functional annotation analyses with Catmap

21 March 2017

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21 March 2017

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The Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling

21 March 2017

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A new class of hexahelical insect proteins revealed as putative carriers of small hydrophobic ligands

21 March 2017

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 March 2017

1 reference

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Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

21 March 2017

1 reference

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Exploration, normalization, and summaries of high density oligonucleotide array probe level data

21 March 2017

1 reference

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Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans

21 March 2017

1 reference

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Summaries of Affymetrix GeneChip probe level data

21 March 2017

1 reference

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A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

21 March 2017

1 reference

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A C. elegans mutant that lives twice as long as wild type

21 March 2017

1 reference

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Functional interaction between beta-catenin and FOXO in oxidative stress signaling

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Normalization of cDNA microarray data

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Many sequence variants affecting diversity of adult human height

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Extended longevity in mice lacking the insulin receptor in adipose tissue

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Cell-nonautonomous effects of dFOXO/DAF-16 in aging

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Activin signaling targeted by insulin/dFOXO regulates aging and muscle proteostasis in Drosophila

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Misregulation of an adaptive metabolic response contributes to the age-related disruption of lipid homeostasis in Drosophila

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Physiological and stem cell compartmentalization within the Drosophila midgut

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

FOXO3 shares common targets with ASCL1 genome-wide and inhibits ASCL1-dependent neurogenesis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Genome-wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

FOXOs: signalling integrators for homeostasis maintenance

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Intestinal barrier dysfunction links metabolic and inflammatory markers of aging to death in Drosophila.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

The relationship between long-range chromatin occupancy and polymerization of the Drosophila ETS family transcriptional repressor Yan

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

The yeast forkhead transcription factors fkh1 and fkh2 regulate lifespan and stress response together with the anaphase-promoting complex

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

MAPK/ERK signaling regulates insulin sensitivity to control glucose metabolism in Drosophila

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Modulation of longevity and tissue homeostasis by the Drosophila PGC-1 homolog.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Genome-wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

A genome-scale shRNA resource for transgenic RNAi in Drosophila

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

dFOXO-independent effects of reduced insulin-like signaling in Drosophila

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

A cis-regulatory map of the Drosophila genome.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Lifespan extension by increased expression of the Drosophila homologue of the IGFBP7 tumour suppressor

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

DamID in C. elegans reveals longevity-associated targets of DAF-16/FoxO

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Expression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independently of dietary restriction.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Starr: Simple Tiling ARRay analysis of Affymetrix ChIP-chip data

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Molecular evolution and functional characterization of Drosophila insulin-like peptides

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Neuronal expression of a single-subunit yeast NADH-ubiquinone oxidoreductase (Ndi1) extends Drosophila lifespan

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Reduction of DILP2 in Drosophila triages a metabolic phenotype from lifespan revealing redundancy and compensation among DILPs

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Downregulation of vertebrate Tel (ETV6) and Drosophila Yan is facilitated by an evolutionarily conserved mechanism of F-box-mediated ubiquitination

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

FOXO-binding partners: it takes two to tango

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Drosophila lifespan control by dietary restriction independent of insulin-like signaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Optimization of dietary restriction protocols in Drosophila

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Evolutionary conservation of regulated longevity assurance mechanisms

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Ringo--an R/Bioconductor package for analyzing ChIP-chip readouts

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Prospero acts as a binary switch between self-renewal and differentiation in Drosophila neural stem cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Transcriptional feedback control of insulin receptor by dFOXO/FOXO1.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Tel/Etv6 is an essential and selective regulator of adult hematopoietic stem cell survival

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Myc-induced proliferation and transformation require Akt-mediated phosphorylation of FoxO proteins

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Control of cell number by Drosophila FOXO: downstream and feedback regulation of the insulin receptor pathway

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Absence of transitive and systemic pathways allows cell-specific and isoform-specific RNAi in Drosophila

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Genes expressed in the Drosophila head reveal a role for fat cells in sex-specific physiology

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

The odorant-binding proteins of Drosophila melanogaster: annotation and characterization of a divergent gene family

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

FOXO/4E-BP Signaling in Drosophila Muscles Regulates Organism-wide Proteostasis during Aging

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

The ETS domain protein pointed-P2 is a target of MAP kinase in the sevenless signal transduction pathway

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

The activities of two Ets-related transcription factors required for Drosophila eye development are modulated by the Ras/MAPK pathway

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Negative control of photoreceptor development in Drosophila by the product of the yan gene, an ETS domain protein

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

Long-lived Drosophila with overexpressed dFOXO in adult fat body

31 May 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1004619

Association of the FOXO3A locus with extreme longevity in a southern Italian centenarian study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1004619

Nutrient availability regulates SIRT1 through a forkhead-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1004619

Nutritional control of protein biosynthetic capacity by insulin via Myc in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1004619

Characterization of the Drosophila gene-switch system in aging studies: a cautionary tale.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1004619

Dynamics of the action of dFOXO on adult mortality in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1004619

Role of dFOXO in lifespan extension by dietary restriction in Drosophila melanogaster: not required, but its activity modulates the response

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1004619

Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1004619

Characterization of the Drosophila insulin receptor promoter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1004619

Control of endothelial sprouting by a Tel–CtBP complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1004619

Yan functions as a general inhibitor of differentiation and is negatively regulated by activation of the Ras1/MAPK pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1004619

Ras pathway specificity is determined by the integration of multiple signal-activated and tissue-restricted transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1004619

Morphological and molecular characterization of adult midgut compartmentalization in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1004619

BoolNet--an R package for generation, reconstruction and analysis of Boolean networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1004619

Haplotypes in the human Foxo1a and Foxo3a genes; impact on disease and mortality at old age

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1004619

The role of yan in mediating the choice between cell division and differentiation

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169242

10.1371/JOURNAL.PGEN.1004619

28 November 2018

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25232726 AND SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25232726 AND SRC:MED&resulttype=core&format=json

16 February 2020

PubMed publication ID

25232726

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25232726 AND SRC:MED&resulttype=core&format=json