(Q24645557)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9405673 AND SRC:MED&resulttype=core&format=json

8 November 2019

title

The anticoagulant activation of antithrombin by heparin (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9405673 AND SRC:MED&resulttype=core&format=json

8 November 2019

1 reference

1 reference

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9405673 AND SRC:MED&resulttype=core&format=json

8 November 2019

Robert N. Pike

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9405673 AND SRC:MED&resulttype=core&format=json

8 November 2019

author name string

L Jin

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9405673 AND SRC:MED&resulttype=core&format=json

8 November 2019

R Skinner

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9405673 AND SRC:MED&resulttype=core&format=json

8 November 2019

M Petitou

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9405673 AND SRC:MED&resulttype=core&format=json

8 November 2019

R W Carrell

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9405673 AND SRC:MED&resulttype=core&format=json

8 November 2019

language of work or name

English

0 references

publication date

1 December 1997

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9405673 AND SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

8 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9405673 AND SRC:MED&resulttype=core&format=json

8 November 2019

volume

94

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9405673 AND SRC:MED&resulttype=core&format=json

8 November 2019

issue

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9405673 AND SRC:MED&resulttype=core&format=json

8 November 2019

page(s)

14683-14688

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9405673 AND SRC:MED&resulttype=core&format=json

The 2.6 A structure of antithrombin indicates a conformational change at the heparin binding site

8 November 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25092

Inhibitory conformation of the reactive loop of alpha 1-antitrypsin

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25092

Crystal structure of cleaved bovine antithrombin III at 3.2 A resolution

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25092

Biological implications of a 3 A structure of dimeric antithrombin

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25092

The intact and cleaved human antithrombin III complex as a model for serpin–proteinase interactions

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25092

The CCP4 suite: programs for protein crystallography

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25092

Role of the antithrombin-binding pentasaccharide in heparin acceleration of antithrombin-proteinase reactions. Resolution of the antithrombin conformational change contribution to heparin rate enhancement

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25092

7 April 2017

Antithrombin and heparin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25092

Heparin-dependent Modification of the Reactive Center Arginine of Antithrombin and Consequent Increase in Heparin Binding Affinity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25092

Heparin-induced thrombocytopenia and thrombosis: a prospective analysis of the incidence in patients with heart and cerebrovascular diseases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25092

Requirement of lysine residues outside of the proposed pentasaccharide binding region for high affinity heparin binding and activation of human antithrombin III.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25092

Transmission of conformational change from the heparin binding site to the reactive center of antithrombin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25092

Acceleration of thrombin-antithrombin complex formation in rat hindquarters via heparinlike molecules bound to the endothelium

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25092

Anticoagulant activities of heparin oligosaccharides and their neutralization by platelet factor 4

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25092

Human alpha 1-proteinase inhibitor. Crystal structure analysis of two crystal modifications, molecular model and preliminary analysis of the implications for function

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25092

Proposed heparin binding site in antithrombin based on arginine 47. A new variant Rouen-II, 47 Arg to Ser

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25092

Implications of the three-dimensional structure of alpha 1-antitrypsin for structure and function of serpins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25092

Targeting the glycosaminoglycan-binding sites on proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25092

Role of arginine 132 and lysine 133 in heparin binding to and activation of antithrombin

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25092

Mechanism of heparin activation of antithrombin. Evidence for reactive center loop preinsertion with expulsion upon heparin binding

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25092

Further characterization of the antithrombin-binding sequence in heparin

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25092

Specific modification of the functional arginine residue in soybean trypsin inhibitor (Kunitz) by peptidylarginine deiminase.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25092

Inactivation of human antithrombin by neutrophil elastase. Kinetics of the heparin-dependent reaction.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25092

Characterization of specific receptors for vasopressin in the pituitary gland

30 May 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.94.26.14683

Structural basis for serpin inhibitor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.94.26.14683

AMoRe: an automated package for molecular replacement

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.94.26.14683

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.94.26.14683

Mobile reactive centre of serpins and the control of thrombosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.94.26.14683

Immunologic evidence for insertion of the reactive-bond loop of antithrombin into the A .beta.-sheet of the inhibitor during trapping of target proteinases

21 January 2018

1 reference

12 December 2020

A mechanism for heparin-induced potentiation of antithrombin III

1 reference

12 December 2020

Antithrombin Glasgow, 393 arg to his: A P1reactive site variant with increased heparin affinity but no thrombin inhibitory activity

1 reference

12 December 2020

Structure-activity relationship in heparin: a synthetic pentasaccharide with high affinity for antithrombin III and eliciting high anti-factor Xa activity

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.94.26.14683

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9405673 AND SRC:MED&resulttype=core&format=json

8 November 2019

ADS bibcode

1997PNAS...9414683J

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9405673 AND SRC:MED&resulttype=core&format=json

8 November 2019

PubMed publication ID

9405673

2 references