(Q24339160)

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A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic

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A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic (English)

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phosphoinositide-3-kinase regulatory subunit 4

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GOA release 2020-03-11

Phosphatidylinositol 3-kinase catalytic subunit type 3

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GOA release 2020-03-11

SH3 domain containing GRB2 like, endophilin B1

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GOA release 2020-03-11

UV radiation resistance associated

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GOA release 2020-03-11

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GOA release 2020-03-11

receptor catabolic process

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GOA release 2020-03-11

Harald Stenmark

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3

object named as

Knut Liestøl

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Sigrid B. Thoresen

1

object named as

Sigrid B Thoresen

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author name string

Nina Marie Pedersen

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language of work or name

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publication date

10 December 2010

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Experimental Cell Research

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316

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20

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3368-78

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Endosomal phosphoinositides and human diseases

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https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

PI3P signaling regulates receptor sorting but not transport in the endosomal pathway

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https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Overexpression of a rat kinase-deficient phosphoinositide 3-kinase, Vps34p, inhibits cathepsin D maturation

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https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Gene silencing reveals a specific function of hVps34 phosphatidylinositol 3-kinase in late versus early endosomes

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https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Defective downregulation of receptor tyrosine kinases in cancer

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https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody

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https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells

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https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Tetraploidy, aneuploidy and cancer

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https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Deregulated Aurora-B induced tetraploidy promotes tumorigenesis

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https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Aurora B-mediated abscission checkpoint protects against tetraploidization

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https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

The regulation and function of Class III PI3Ks: novel roles for Vps34.

1 reference

https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Role of Rab5 in the Recruitment of hVps34/p150 to the Early Endosome

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https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Phosphatidylinositol-3-OH kinases are Rab5 effectors.

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https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Characterization of p150, an adaptor protein for the human phosphatidylinositol (PtdIns) 3-kinase. Substrate presentation by phosphatidylinositol transfer protein to the p150.Ptdins 3-kinase complex

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https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network

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https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG

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https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function

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https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis

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https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG

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https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae

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https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells

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https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages

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https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex

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https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Functional specificity of the mammalian Beclin-Vps34 PI 3-kinase complex in macroautophagy versus endocytosis and lysosomal enzyme trafficking

1 reference

https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Loss of Bif-1 suppresses Bax/Bak conformational change and mitochondrial apoptosis

1 reference

https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Frameshift mutation of UVRAG, an autophagy-related gene, in gastric carcinomas with microsatellite instability

1 reference

https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Manipulation of nonsense mediated decay identifies gene mutations in colon cancer Cells with microsatellite instability

1 reference

https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Ascending colon cancer with hepatic metastasis and cholecystolithiasis in a patient with situs inversus totalis without any expression of UVRAG mRNA: report of a case

1 reference

https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Detailed map of a region commonly amplified at 11q13-->q14 in human breast carcinoma

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https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Induction of autophagy and inhibition of tumorigenesis by beclin 1

1 reference

https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

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https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

1 reference

https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes

1 reference

https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Hrs recruits clathrin to early endosomes

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https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis

1 reference

https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Differential functions of Hrs and ESCRT proteins in endocytic membrane trafficking.

1 reference

https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Endophilin B1 as a novel regulator of nerve growth factor/ TrkA trafficking and neurite outgrowth.

1 reference

https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking.

1 reference

https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

UVRAG reveals its second nature

1 reference

https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Sorting nexin-1 mediates tubular endosome-to-TGN transport through coincidence sensing of high- curvature membranes and 3-phosphoinositides

1 reference

https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Mechanism of endophilin N-BAR domain-mediated membrane curvature

1 reference

https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Endophilin BAR domain drives membrane curvature by two newly identified structure-based mechanisms

1 reference

https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins

1 reference

https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Chmp1A functions as a novel tumor suppressor gene in human embryonic kidney and ductal pancreatic tumor cells

1 reference

https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

HCRP1, a novel gene that is downregulated in hepatocellular carcinoma, encodes a growth-inhibitory protein

1 reference

https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

p53 accumulation, defective cell proliferation, and early embryonic lethality in mice lacking tsg101.

1 reference

https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Tumor suppressor properties of the ESCRT-II complex component Vps25 in Drosophila

1 reference

https://api.crossref.org/works/10.1016/J.YEXCR.2010.07.008

7 January 2021

Identifiers

10.1016/J.YEXCR.2010.07.008

1 reference

Consolidated OpenCitations Corpus – April 2017

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OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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