(Q24303889)

Ubiquitin protein ligase E3 component n-recognin 2

GOA release 2020-03-11

1 reference

cellular response to leucine

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Kanako Kume

1

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Yosuke Iizumi

2

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Masashi Shimada

3

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Yuki Ito

4

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Tsutomu Kishi

5

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Yuki Yamaguchi

6

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Hiroshi Handa

Development and application of high-performance affinity beads: toward chemical biology and drug discovery

7

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language of work or name

English

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publication date

1 April 2010

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published in

Genes to Cells

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volume

15

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issue

4

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page(s)

339-49

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cites work

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Effect of a dipeptide inhibiting ubiquitin-mediated protein degradation nerve-dependent limb regeneration in the newt.

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Dipeptide inhibitors of ubiquitin-mediated protein turnover prevent growth factor-induced neurite outgrowth in rat pheochromocytoma PC12 cells

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Regulation of global and specific mRNA translation by oral administration of branched-chain amino acids

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

mTOR integrates amino acid- and energy-sensing pathways

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Capsaicin binds to prohibitin 2 and displaces it from the mitochondria to the nucleus

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Nutrient sensing and metabolic decisions

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

TOR signaling in growth and metabolism

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein alpha subunit at the endosome

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

SKAR links pre-mRNA splicing to mTOR/S6K1-mediated enhanced translation efficiency of spliced mRNAs

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Mammalian target of rapamycin complex 1: signalling inputs, substrates and feedback mechanisms.

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

The amino acid sensitive TOR pathway from yeast to mammals.

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Structural requirement of leucine for activation of p70 S6 kinase

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

TSC2 mediates cellular energy response to control cell growth and survival

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Peptides accelerate their uptake by activating a ubiquitin-dependent proteolytic pathway

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Control of p70 s6 kinase by kinase activity of FRAP in vivo

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

High-performance affinity beads for identifying drug receptors

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Regulation of TORC1 by Rag GTPases in nutrient response

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Degradation of DIAP1 by the N-end rule pathway is essential for regulating apoptosis.

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Deficiency of UBR1, a ubiquitin ligase of the N-end rule pathway, causes pancreatic dysfunction, malformations and mental retardation (Johanson-Blizzard syndrome)

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase.

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

RGS4 and RGS5 are in vivo substrates of the N-end rule pathway

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Impaired neurogenesis and cardiovascular development in mice lacking the E3 ubiquitin ligases UBR1 and UBR2 of the N-end rule pathway.

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Pairs of dipeptides synergistically activate the binding of substrate by ubiquitin ligase through dissociation of its autoinhibitory domain

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

The N-end rule: functions, mysteries, uses

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Neurite outgrowth in PC12 cells. Distinguishing the roles of ubiquitylation and ubiquitin-dependent proteolysis

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Immunopurified mammalian target of rapamycin phosphorylates and activates p70 S6 kinase alpha in vitro

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Rheb binding to mammalian target of rapamycin (mTOR) is regulated by amino acid sufficiency

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Regulation of an activated S6 kinase 1 variant reveals a novel mammalian target of rapamycin phosphorylation site

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

The substrate recognition domains of the N-end rule pathway

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Amino acids induce peptide uptake via accelerated degradation of CUP9, the transcriptional repressor of the PTR2 peptide transporter

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

RalA functions as an indispensable signal mediator for the nutrient-sensing system

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase.

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Orally administered leucine stimulates protein synthesis in skeletal muscle of postabsorptive rats in association with increased eIF4F formation.

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

A new mechanism of methotrexate action revealed by target screening with affinity beads

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Degradation of G alpha by the N-end rule pathway

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Construction and analysis of mouse strains lacking the ubiquitin ligase UBR1 (E3alpha) of the N-end rule pathway

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Genetic and biochemical analysis of the yeast plasma membrane Ssy1p-Ptr3p-Ssy5p sensor of extracellular amino acids

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Female Lethality and Apoptosis of Spermatocytes in Mice Lacking the UBR2 Ubiquitin Ligase of the N-End Rule Pathway

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Amino acid effects on translational repressor 4E-BP1 are mediated primarily by L-leucine in isolated adipocytes

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Leucine. A possible regulator of protein turnover in muscle

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

A genome-wide screen for regulators of TORC1 in response to amino acid starvation reveals a conserved Npr2/3 complex

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021

Adenine nucleotide translocator transports haem precursors into mitochondria

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2010.01385.X

7 January 2021