(Q22009535)

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The tumor suppressor EXT-like gene EXTL2 encodes an alpha1, 4-N-acetylhexosaminyltransferase that transfers N-acetylgalactosamine and N-acetylglucosamine to the common glycosaminoglycan-protein linkage region. The key enzyme for the chain initiation of heparan sulfate (English)

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Exostosin like glycosyltransferase 2

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GOA release 2020-03-11

alpha-1,4-N-acetylgalactosaminyltransferase activity

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GOA release 2020-03-11

author name string

H Kitagawa

1

author given names

H

author last names

Kitagawa

1 reference

PubMed publication ID

7 February 2023

H Shimakawa

2

author given names

H

author last names

Shimakawa

1 reference

PubMed publication ID

7 February 2023

K Sugahara

3

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K

author last names

Sugahara

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PubMed publication ID

7 February 2023

language of work or name

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publication date

14 May 1999

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Journal of Biological Chemistry

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274

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20

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13933-7

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Molecular Cloning and Expression of Glucuronyltransferase I Involved in the Biosynthesis of the Glycosaminoglycan-Protein Linkage Region of Proteoglycans

1 reference

https://api.crossref.org/works/10.1074/JBC.274.20.13933

21 January 2018

The putative tumor suppressors EXT1 and EXT2 are glycosyltransferases required for the biosynthesis of heparan sulfate

1 reference

https://api.crossref.org/works/10.1074/JBC.274.20.13933

21 January 2018

Assignment of a second locus for multiple exostoses to the pericentromeric region of chromosome 11

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https://api.crossref.org/works/10.1074/JBC.274.20.13933

21 January 2018

A gene for hereditary multiple exostoses maps to chromosome 19p.

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https://api.crossref.org/works/10.1074/JBC.274.20.13933

21 January 2018

Structure, Chromosomal Location, and Expression Profile of EXTR1 and EXTR2, New Members of the Multiple Exostoses Gene Family

1 reference

https://api.crossref.org/works/10.1074/JBC.274.20.13933

21 January 2018

Identification and localization of the gene for EXTL, a third member of the multiple exostoses gene family

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https://api.crossref.org/works/10.1074/JBC.274.20.13933

21 January 2018

Identification of a third EXT-like gene (EXTL3) belonging to the EXT gene family.

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https://api.crossref.org/works/10.1074/JBC.274.20.13933

21 January 2018

N-acetylgalactosamine (GalNAc) transfer to the common carbohydrate-protein linkage region of sulfated glycosaminoglycans. Identification of UDP-GalNAc:chondro-oligosaccharide alpha-N-acetylgalactosaminyltransferase in fetal bovine serum.

1 reference

https://api.crossref.org/works/10.1074/JBC.274.20.13933

21 January 2018

-N-Acetylgalactosamine-capping of chondroitin sulfate core region oligosaccharides primed on xylosides

1 reference

https://api.crossref.org/works/10.1074/JBC.274.20.13933

21 January 2018

Identification and characterization of a novel UDP-GalNAc:GlcAbeta-R alpha1,4-N-acetylgalactosaminyltransferase from a human sarcoma cell line

1 reference

https://api.crossref.org/works/10.1074/JBC.274.20.13933

21 January 2018

Heparan sulfate undergoes specific structural changes during the progression from human colon adenoma to carcinoma in vitro.

1 reference

https://api.crossref.org/works/10.1074/JBC.274.20.13933

21 January 2018

Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion

1 reference

https://api.crossref.org/works/10.1074/JBC.274.20.13933

21 January 2018

Spatially restricted expression of pipe in the Drosophila egg chamber defines embryonic dorsal-ventral polarity

1 reference

https://api.crossref.org/works/10.1074/JBC.274.20.13933

21 January 2018

Congenital enterocyte heparan sulphate deficiency with massive albumin loss, secretory diarrhoea, and malnutrition

1 reference

https://api.crossref.org/works/10.1074/JBC.274.20.13933

7 January 2021

based on heuristic

inferred from DOI database lookup

Assessment of glycosaminoglycan-protein linkage tetrasaccharides as acceptors for GalNAc- and GlcNAc-transferases from mouse mastocytoma

1 reference

https://api.crossref.org/works/10.1074/JBC.274.20.13933

7 January 2021

based on heuristic

inferred from DOI database lookup

Partial purification and substrate specificity of heparan sulfate α-N-acetylglucosaminyltransferase I: synthesis, NMR spectroscopic characterization and in vitro assays of two aryl tetrasaccharides

1 reference

https://api.crossref.org/works/10.1074/JBC.274.20.13933

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of serum β-glucuronyltransferase involved in chondroitin sulfate biosynthesis

1 reference

https://api.crossref.org/works/10.1074/JBC.274.20.13933

7 January 2021

based on heuristic

inferred from DOI database lookup

The natural history of hereditary multiple exostoses

1 reference

https://api.crossref.org/works/10.1074/JBC.274.20.13933

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1074/JBC.274.20.13933

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

release_xpt7ict5gvgdjmm5nmdtc4fj7a

1 reference

https://api.fatcat.wiki/v0/release/xpt7ict5gvgdjmm5nmdtc4fj7a

24 November 2022

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mapped directly with Wikidata item

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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