(Q22008781)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10025408 AND SRC:MED&resulttype=core&format=json

10 November 2019

title

Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12 (English)

1 reference

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10 November 2019

0 references

3

J Massagué

J

Massagué

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10025408 AND SRC:MED&resulttype=core&format=json

10 November 2019

M Huse

1

M

Huse

1 reference

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10 November 2019

Y G Chen

series ordinal

2

author given names

Y G

author last names

Chen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10025408 AND SRC:MED&resulttype=core&format=json

10 November 2019

J Kuriyan

series ordinal

4

author given names

J

author last names

Kuriyan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10025408 AND SRC:MED&resulttype=core&format=json

10 November 2019

language of work or name

English

0 references

publication date

1 February 1999

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10025408 AND SRC:MED&resulttype=core&format=json

10 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10025408 AND SRC:MED&resulttype=core&format=json

10 November 2019

volume

96

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10025408 AND SRC:MED&resulttype=core&format=json

10 November 2019

issue

3

1 reference

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10 November 2019

page(s)

425-436

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10025408 AND SRC:MED&resulttype=core&format=json

Magnetic resonance and kinetic studies of the manganese(II) ion and substrate complexes of the catalytic subunit of adenosine 3',5'-monophosphate dependent protein kinase from bovine heart

10 November 2019

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The CCP4 suite: programs for protein crystallography

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FKBP-12 recognition is dispensable for signal generation by type I transforming growth factor-beta receptors.

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Biochemical evidence for the autophosphorylation and transphosphorylation of transforming growth factor beta receptor kinases

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7 January 2021

Mechanism of TGFβ receptor inhibition by FKBP12

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7 January 2021

Determinants of specificity in TGF-beta signal transduction.

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7 January 2021

A kinase subdomain of transforming growth factor-β (TGF-β) type I receptor determines the TGF-β intracellular signaling specificity

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7 January 2021

Transforming growth factor-beta (TGF-beta)-induced down-regulation of cyclin A expression requires a functional TGF-beta receptor complex. Characterization of chimeric and truncated type I and type II receptors

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Structural basis for the autoinhibition of calcium/calmodulin-dependent protein kinase I

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X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex

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7 January 2021

Substrate specificities of the peptidyl prolyl cis-trans isomerase activities of cyclophilin and FK-506 binding protein: evidence for the existence of a family of distinct enzymes

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TGF-β signalling from cell membrane to nucleus through SMAD proteins

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7 January 2021

The types II and III transforming growth factor-beta receptors form homo-oligomers

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7 January 2021

Insights into autoregulation from the crystal structure of twitchin kinase

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7 January 2021

Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog

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7 January 2021

Crystal structure of the tyrosine kinase domain of the human insulin receptor

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7 January 2021

Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex

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7 January 2021

Active and inactive protein kinases: structural basis for regulation

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7 January 2021

Not your average density.

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7 January 2021

Crystal Structure of the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase

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7 January 2021

The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase

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7 January 2021

[27] Maximum-likelihood heavy-atom parameter refinement for multiple isomorphous replacement and multiwavelength anomalous diffraction methods.

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7 January 2021

The type II transforming growth factor-beta receptor autophosphorylates not only on serine and threonine but also on tyrosine residues

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7 January 2021

Dual-specificity protein kinases: will any hydroxyl do?

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7 January 2021

[29] Identification of functional residues and secondary structure from protein multiple sequence alignment

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7 January 2021

Signaling by chimeric erythropoietin-TGF-beta receptors: homodimerization of the cytoplasmic domain of the type I TGF-beta receptor and heterodimerization with the type II receptor are both required for intracellular signal transduction.

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7 January 2021

The transforming growth factor-beta family

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7 January 2021

TGF-beta signal transduction

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7 January 2021

Structure of the FGF receptor tyrosine kinase domain reveals a novel autoinhibitory mechanism

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7 January 2021

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

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7 January 2021

Characterization of the Interaction of FKBP12 with the Transforming Growth Factor-β Type I Receptorin Vivo

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7 January 2021

Processing of X-ray diffraction data collected in oscillation mode

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7 January 2021

Two structures of the catalytic domain of phosphorylase kinase: an active protein kinase complexed with substrate analogue and product

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7 January 2021

Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex

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7 January 2021

Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands

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7 January 2021

Oligomerization and phosphorylation of the Ire1p kinase during intracellular signaling from the endoplasmic reticulum to the nucleus

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7 January 2021

Cardiac defects and altered ryanodine receptor function in mice lacking FKBP12

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7 January 2021

Crystal structure of the Src family tyrosine kinase Hck

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7 January 2021

Probing the role of homomeric and heteromeric receptor interactions in TGF-beta signaling using small molecule dimerizers

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7 January 2021

TGF-beta-signaling with small molecule FKBP12 antagonists that bind myristoylated FKBP12-TGF-beta type I receptor fusion proteins

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7 January 2021

Atomic structure of FKBP-FK506, an immunophilin-immunosuppressant complex

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7 January 2021

Specific interaction of type I receptors of the TGF-beta family with the immunophilin FKBP-12

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7 January 2021

The immunophilin FKBP12 functions as a common inhibitor of the TGF beta family type I receptors.

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7 January 2021

The structure of mitogen-activated protein kinase p38 at 2.1-A resolution

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7 January 2021

Complementation between kinase-defective and activation-defective TGF-beta receptors reveals a novel form of receptor cooperativity essential for signaling.

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7 January 2021

Comparative X-ray structures of the major binding protein for the immunosuppressant FK506 (tacrolimus) in unliganded form and in complex with FK506 and rapamycin

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7 January 2021

Mechanism of activation of the TGF-beta receptor

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7 January 2021

Three-dimensional structure of the tyrosine kinase c-Src

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7 January 2021

Crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MgATP and peptide inhibitor

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7 January 2021

The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification 1

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7 January 2021

10.1016/S0092-8674(00)80555-3

Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10025408 AND SRC:MED&resulttype=core&format=json

10 November 2019

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017