(Q21989850)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q99LX0

Class I glutamine amidotransferase-like

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q99LX0

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

DJ-1/PfpI domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

4 references

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

mRNA binding

protein homodimerization activity

3 references

9 May 2019

Park7 interacts with p47(phox) to direct NADPH oxidase-dependent ROS production and protect against sepsis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

hsp70-DnaJ chaperone pair prevents nitric oxide- and CHOP-induced apoptosis by inhibiting translocation of Bax to mitochondria

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

DJ-1 interacts with RACK1 and protects neurons from oxidative-stress-induced apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

peroxiredoxin activity

1 reference

9 May 2019

DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

copper ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

1 reference

9 May 2019

protein deglycase activity

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

protein-containing complex binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

cell component

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

4 references

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

cytosol

5 references

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99LX0&geneProductId=UniProtKB:Q99LX0

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99LX0&geneProductId=UniProtKB:Q99LX0

31 January 2018

DJ-1 Cleavage by Matrix Metalloproteinase 3 Mediates Oxidative Stress-Induced Dopaminergic Cell Death

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99LX0&geneProductId=UniProtKB:Q99LX0

31 January 2018

Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99LX0&geneProductId=UniProtKB:Q99LX0

31 January 2018

The caspase 6 derived N-terminal fragment of DJ-1 promotes apoptosis via increased ROS production

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99LX0&geneProductId=UniProtKB:Q99LX0

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

1 reference

9 May 2019

mitochondrial intermembrane space

1 reference

9 May 2019

Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

mitochondrion

8 references

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99LX0&geneProductId=UniProtKB:Q99LX0

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99LX0&geneProductId=UniProtKB:Q99LX0

31 January 2018

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99LX0&geneProductId=UniProtKB:Q99LX0

31 January 2018

DJ-1 Cleavage by Matrix Metalloproteinase 3 Mediates Oxidative Stress-Induced Dopaminergic Cell Death

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99LX0&geneProductId=UniProtKB:Q99LX0

31 January 2018

Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99LX0&geneProductId=UniProtKB:Q99LX0

31 January 2018

The caspase 6 derived N-terminal fragment of DJ-1 promotes apoptosis via increased ROS production

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99LX0&geneProductId=UniProtKB:Q99LX0

31 January 2018

A mitochondrial protein compendium elucidates complex I disease biology

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99LX0&geneProductId=UniProtKB:Q99LX0

31 January 2018

DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99LX0&geneProductId=UniProtKB:Q99LX0

neuron projection

1 reference

9 May 2019

DJ-1 interacts with RACK1 and protects neurons from oxidative-stress-induced apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99LX0&geneProductId=UniProtKB:Q99LX0

5 references

31 January 2018

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99LX0&geneProductId=UniProtKB:Q99LX0

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99LX0&geneProductId=UniProtKB:Q99LX0

31 January 2018

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99LX0&geneProductId=UniProtKB:Q99LX0

31 January 2018

The caspase 6 derived N-terminal fragment of DJ-1 promotes apoptosis via increased ROS production

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99LX0&geneProductId=UniProtKB:Q99LX0

endoplasmic reticulum

1 reference

9 May 2019

The caspase 6 derived N-terminal fragment of DJ-1 promotes apoptosis via increased ROS production

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

membrane raft

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99LX0&geneProductId=UniProtKB:Q99LX0

1 reference

31 January 2018

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

1 reference

9 May 2019

mitochondrial matrix

1 reference

9 May 2019

Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

cell body

1 reference

9 May 2019

DJ-1 interacts with RACK1 and protects neurons from oxidative-stress-induced apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

presynapse

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

6 references

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

The caspase 6 derived N-terminal fragment of DJ-1 promotes apoptosis via increased ROS production

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

mitochondrion

8 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

DJ-1 Cleavage by Matrix Metalloproteinase 3 Mediates Oxidative Stress-Induced Dopaminergic Cell Death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

The caspase 6 derived N-terminal fragment of DJ-1 promotes apoptosis via increased ROS production

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

A mitochondrial protein compendium elucidates complex I disease biology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

HDA

cytosol

6 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

DJ-1 Cleavage by Matrix Metalloproteinase 3 Mediates Oxidative Stress-Induced Dopaminergic Cell Death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

The caspase 6 derived N-terminal fragment of DJ-1 promotes apoptosis via increased ROS production

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

axon

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

sperm head

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

mitochondrial respiratory chain complex I

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

negative regulation of protein binding

biological process

synaptic transmission, dopaminergic

1 reference

9 May 2019

Age-dependent motor deficits and dopaminergic dysfunction in DJ-1 null mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

cell population proliferation

TAS

1 reference

1 January 2018

Molecular cloning of human and mouse DJ-1 genes and identification of Sp1-dependent activation of the human DJ-1 promoter

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99LX0&geneProductId=UniProtKB:Q99LX0

cellular response to glyoxal

TAS

positive regulation of reactive oxygen species biosynthetic process

3 references

1 reference

9 May 2019

The caspase 6 derived N-terminal fragment of DJ-1 promotes apoptosis via increased ROS production

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

positive regulation of oxidative phosphorylation uncoupler activity

1 reference

9 May 2019

Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

negative regulation of protein catabolic process

1 reference

9 May 2019

Regulation of the VHL/HIF-1 pathway by DJ-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

regulation of neuron apoptotic process

negative regulation of cell death

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

glycolate biosynthetic process

3 references

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

1 reference

9 May 2019

positive regulation of mitochondrial electron transport, NADH to ubiquinone

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

DJ-1 binds to mitochondrial complex I and maintains its activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

inflammatory response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

1 reference

9 May 2019

negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

negative regulation of oxidative stress-induced neuron death

1 reference

9 May 2019

Regulation of the VHL/HIF-1 pathway by DJ-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

protein stabilization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

5 references

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

membrane depolarization

1 reference

9 May 2019

Enhanced sensitivity of DJ-1-deficient dopaminergic neurons to energy metabolism impairment: role of Na /K ATPase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

mitochondrion organization

1 reference

9 May 2019

Reduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson's disease-associated protein DJ-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

negative regulation of apoptotic process

3 references

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

1 reference

9 May 2019

dopamine uptake involved in synaptic transmission

1 reference

9 May 2019

Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial Parkinsonism-linked gene DJ-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

negative regulation of hydrogen peroxide-induced neuron death

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

DJ-1 interacts with RACK1 and protects neurons from oxidative-stress-induced apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

regulation of inflammatory response

1 reference

9 May 2019

Regulation of astrocyte inflammatory responses by the Parkinson's disease-associated gene DJ-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

response to hydrogen peroxide

detoxification of copper ion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

4 references

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

Parkinson disease protein DJ-1 binds metals and protects against metal-induced cytotoxicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

membrane hyperpolarization

1 reference

9 May 2019

Enhanced sensitivity of DJ-1-deficient dopaminergic neurons to energy metabolism impairment: role of Na /K ATPase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

detoxification of mercury ion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

4 references

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

Parkinson disease protein DJ-1 binds metals and protects against metal-induced cytotoxicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

1 reference

9 May 2019

cellular response to reactive oxygen species

1 reference

9 May 2019

Enhanced sensitivity of DJ-1-deficient dopaminergic neurons to energy metabolism impairment: role of Na /K ATPase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

negative regulation of protein ubiquitination

hydrogen peroxide metabolic process

3 references

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

positive regulation of gene expression

1 reference

9 May 2019

DJ-1 induces thioredoxin 1 expression through the Nrf2 pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

negative regulation of ubiquitin-protein transferase activity

IC

positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

3 references

1 reference

9 May 2019

The caspase 6 derived N-terminal fragment of DJ-1 promotes apoptosis via increased ROS production

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

cellular response to oxidative stress

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

positive regulation of transcription by RNA polymerase II

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

DJ-1 enhances cell survival through the binding of Cezanne, a negative regulator of NF-kappaB

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

cellular response to hydrogen peroxide

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

cellular oxidant detoxification

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

positive regulation of acute inflammatory response to antigenic stimulus

1 reference

9 May 2019

Park7 interacts with p47(phox) to direct NADPH oxidase-dependent ROS production and protect against sepsis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

positive regulation of NAD(P)H oxidase activity

1 reference

9 May 2019

Park7 interacts with p47(phox) to direct NADPH oxidase-dependent ROS production and protect against sepsis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

glyoxal metabolic process

3 references

protein deglycosylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

1 reference

9 May 2019

methylglyoxal metabolic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

1 reference

9 May 2019

protein deglycation, methylglyoxal removal

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

1 reference

9 May 2019

cellular response to DNA damage stimulus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

1 reference

9 May 2019

insulin secretion

1 reference

9 May 2019

Age- and diet-dependent requirement of DJ-1 for glucose homeostasis in mice with implications for human type 2 diabetes.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

glucose homeostasis

1 reference

9 May 2019

Age- and diet-dependent requirement of DJ-1 for glucose homeostasis in mice with implications for human type 2 diabetes.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

negative regulation of reactive oxygen species biosynthetic process

1 reference

9 May 2019

Age- and diet-dependent requirement of DJ-1 for glucose homeostasis in mice with implications for human type 2 diabetes.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

DNA repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

4 references

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

guanine deglycation

guanine deglycation, glyoxal removal

response to oxidative stress

3 references

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

protein deglycation, glyoxal removal

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

guanine deglycation, glyoxal removal

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

4 references

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

negative regulation of NMDA glutamate receptor activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

positive regulation of fertilization

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LX0

1 reference

InterPro Release 71.0