(Q21982906)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P35438

ionotropic glutamate receptor, metazoa

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P35438

Calmodulin-binding domain C0, NMDA receptor, NR1 subunit, protein family

1 reference

Receptor, ligand binding region, protein family

1 reference

Ionotropic glutamate receptor domain, protein family

1 reference

Ionotropic glutamate receptor, L-glutamate and glycine-binding domain, protein family

1 reference

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

10 August 2016

protein binding

19 references

10 August 2016

9 May 2019

Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Maternal stress produces learning deficits associated with impairment of NMDA receptor-mediated synaptic plasticity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Differential expression and co-assembly of NMDA zeta 1 and epsilon subunits in the mouse cerebellum during postnatal development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

N-methyl-D-aspartate receptor subunits are non-myosin targets of myosin regulatory light chain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Intracellular domains of NMDA receptor subtypes are determinants for long-term potentiation induction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Neto1 is an auxiliary subunit of native synaptic kainate receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Direct interaction of myosin regulatory light chain with the NMDA receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Kinase-independent requirement of EphB2 receptors in hippocampal synaptic plasticity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Increased ethanol resistance and consumption in Eps8 knockout mice correlates with altered actin dynamics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Biochemical evidence for the existence of a pool of unassembled C2 exon-containing NR1 subunits of the mammalian forebrain NMDA receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Molecular characterization and comparison of the components and multiprotein complexes in the postsynaptic proteome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Impaired maturation of dendritic spines without disorganization of cortical cell layers in mice lacking NRG1/ErbB signaling in the central nervous system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Proteomic analysis of NMDA receptor-adhesion protein signaling complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Dual role of the exocyst in AMPA receptor targeting and insertion into the postsynaptic membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Apolipoprotein E receptor 2 interactions with the N-methyl-D-aspartate receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

extracellularly glutamate-gated ion channel activity

1 reference

10 August 2016

calcium channel activity

5 references

10 August 2016

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Functional characterization of a heteromeric NMDA receptor channel expressed from cloned cDNAs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Functional characterization of a heteromeric NMDA receptor channel expressed from cloned cDNAs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

NMDA glutamate receptor activity

1 reference

10 August 2016

ion channel activity

2 references

10 August 2016

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

signaling receptor binding

1 reference

10 August 2016

ionotropic glutamate receptor activity

1 reference

10 August 2016

NMDA glutamate receptor activity

Molecular characterization of N-methyl-D-aspartate receptors expressed in mammalian cells yields evidence for the coexistence of three subunit types within a discrete receptor molecule

16 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

A conditional deletion of the NR1 subunit of the NMDA receptor in adult spinal cord dorsal horn reduces NMDA currents and injury-induced pain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Impaired spatial working memory but spared spatial reference memory following functional loss of NMDA receptors in the dentate gyrus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Cortex-restricted disruption of NMDAR1 impairs neuronal patterns in the barrel cortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Requirement for hippocampal CA3 NMDA receptors in associative memory recall

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

NMDA receptor-dependent regulation of axonal and dendritic branching

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Functional characterization of a heteromeric NMDA receptor channel expressed from cloned cDNAs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Molecular diversity of the NMDA receptor channel

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Ion permeation properties of the cloned mouse epsilon 2/zeta 1 NMDA receptor channel

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Functional characterization of a heteromeric NMDA receptor channel expressed from cloned cDNAs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Molecular diversity of the NMDA receptor channel

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Cloning and expression of the epsilon 4 subunit of the NMDA receptor channel

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

IBA

glycine binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

4 references

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Involvement of NMDA receptors in alcohol-mediated behavior: mice with reduced affinity of the NMDA R1 glycine binding site display an attenuated sensitivity to ethanol

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

enzyme binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

phosphatase binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

voltage-gated cation channel activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

glutamate receptor binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

signaling receptor activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

1 reference

9 May 2019

neurotransmitter binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

protein-containing complex binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

protein heterodimerization activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

protein dimerization activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

ligand-gated ion channel activity involved in regulation of presynaptic membrane potential

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

amyloid-beta binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

cell component

postsynaptic membrane

5 references

10 August 2016

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

9 May 2019

Impaired NMDA receptor-mediated postsynaptic function and blunted NMDA receptor-dependent persistent pain in mice lacking postsynaptic density-93 protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

The receptor tyrosine kinase EphB2 regulates NMDA-dependent synaptic function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

NMDA receptor GluRepsilon/NR2 subunits are essential for postsynaptic localization and protein stability of GluRzeta1/NR1 subunit

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

membrane

1 reference

10 August 2016

synapse

8 references

10 August 2016

9 May 2019

Semaphorin 4B interacts with the post-synaptic density protein PSD-95/SAP90 and is recruited to synapses through a C-terminal PDZ-binding motif

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Control of excitatory and inhibitory synapse formation by neuroligins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

9 May 2019

NR2B tyrosine phosphorylation modulates fear learning as well as amygdaloid synaptic plasticity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Neto1 is an auxiliary subunit of native synaptic kainate receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Intracellular domains of NMDA receptor subtypes are determinants for long-term potentiation induction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Regulation of NMDA receptor trafficking by amyloid-beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

NMDA selective glutamate receptor complex

1 reference

10 August 2016

cell surface

1 reference

10 August 2016

integral component of membrane

2 references

10 August 2016

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

plasma membrane

1 reference

10 August 2016

cell junction

2 references

10 August 2016

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

dendrite

5 references

10 August 2016

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Reelin signaling facilitates maturation of CA1 glutamatergic synapses

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

LTP requires a unique postsynaptic SNARE fusion machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

dendritic spine

1 reference

10 August 2016

postsynaptic density

1 reference

10 August 2016

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

5 references

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

IBA

cell surface

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Reelin signaling facilitates maturation of CA1 glutamatergic synapses

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Reelin signaling facilitates maturation of CA1 glutamatergic synapses

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

postsynaptic density

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

9 May 2019

Phosphorylation state of postsynaptic density proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

NMDA receptor GluRepsilon/NR2 subunits are essential for postsynaptic localization and protein stability of GluRzeta1/NR1 subunit

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

6 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

9 May 2019

Biochemical evidence for the existence of a pool of unassembled C2 exon-containing NR1 subunits of the mammalian forebrain NMDA receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Regional and subunit specific changes in NMDA receptor mRNA and immunoreactivity in mouse brain following chronic ethanol ingestion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

NMDA selective glutamate receptor complex

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Biochemical evidence for the existence of a pool of unassembled C2 exon-containing NR1 subunits of the mammalian forebrain NMDA receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

IBA

dendrite membrane

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

soma

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

synaptic cleft

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

terminal bouton

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

dendritic branch

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

excitatory synapse

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

synaptic membrane

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

hippocampal mossy fiber to CA3 synapse

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

parallel fiber to Purkinje cell synapse

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

postsynaptic density membrane

1 reference

9 May 2019

NMDA receptor GluN2B (GluR epsilon 2/NR2B) subunit is crucial for channel function, postsynaptic macromolecular organization, and actin cytoskeleton at hippocampal CA3 synapses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

integral component of presynaptic membrane

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

negative regulation of neuron apoptotic process

biological process

3 references

10 August 2016

9 May 2019

NMDA receptors promote survival in somatosensory relay nuclei by inhibiting Bax-dependent developmental cell death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

NMDA receptors promote survival in somatosensory relay nuclei by inhibiting Bax-dependent developmental cell death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

synaptic transmission, glutamatergic

3 references

10 August 2016

9 May 2019

Cortex-restricted disruption of NMDAR1 impairs neuronal patterns in the barrel cortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

regulation of respiratory gaseous exchange

4 references

10 August 2016

9 May 2019

NMDA receptor activity in utero averts respiratory depression and anomalous long-term depression in newborn mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Characterization of excitatory amino acid neurotoxicity in N-methyl-D-aspartate receptor-deficient mouse cortical neuronal cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

response to amphetamine

4 references

10 August 2016

9 May 2019

Amphetamine-induced disruption of prepulse inhibition in mice with reduced NMDA receptor function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Amphetamine-induced Fos is reduced in limbic cortical regions but not in the caudate or accumbens in a genetic model of NMDA receptor hypofunction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Balanced NMDA receptor activity in dopamine D1 receptor (D1R)- and D2R-expressing medium spiny neurons is required for amphetamine sensitization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

regulation of membrane potential

1 reference

10 August 2016

calcium ion transport

1 reference

10 August 2016

suckling behavior

4 references

10 August 2016

9 May 2019

NMDA receptor activity in utero averts respiratory depression and anomalous long-term depression in newborn mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Characterization of excitatory amino acid neurotoxicity in N-methyl-D-aspartate receptor-deficient mouse cortical neuronal cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

regulation of long-term neuronal synaptic plasticity

4 references

10 August 2016

9 May 2019

Functional consequences of reduction in NMDA receptor glycine affinity in mice carrying targeted point mutations in the glycine binding site

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Impaired spatial working memory but spared spatial reference memory following functional loss of NMDA receptors in the dentate gyrus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Disrupted motor learning and long-term synaptic plasticity in mice lacking NMDAR1 in the striatum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

adult locomotory behavior

3 references

10 August 2016

9 May 2019

Functional consequences of reduction in NMDA receptor glycine affinity in mice carrying targeted point mutations in the glycine binding site

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Mice with reduced NMDA receptor expression display behaviors related to schizophrenia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

regulation of neuron apoptotic process

3 references

memory

4 references

10 August 2016

9 May 2019

Formation of temporal memory requires NMDA receptors within CA1 pyramidal neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Dentate gyrus NMDA receptors mediate rapid pattern separation in the hippocampal network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Enrichment induces structural changes and recovery from nonspatial memory deficits in CA1 NMDAR1-knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

excitatory postsynaptic potential

3 references

10 August 2016

9 May 2019

Inducible and reversible NR1 knockout reveals crucial role of the NMDA receptor in preserving remote memories in the brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Intracellular domains of NMDA receptor subtypes are determinants for long-term potentiation induction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

associative learning

4 references

10 August 2016

9 May 2019

The contribution of NMDA receptor signaling in the corticobasal ganglia reward network to appetitive Pavlovian learning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Requirement for hippocampal CA3 NMDA receptors in associative memory recall

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Hippocampal CA3 NMDA receptors are crucial for memory acquisition of one-time experience

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

cation transport

4 references

10 August 2016

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Ion permeation properties of the cloned mouse epsilon 2/zeta 1 NMDA receptor channel

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

respiratory gaseous exchange by respiratory system

3 references

10 August 2016

14 February 2019

Characterization of excitatory amino acid neurotoxicity in N-methyl-D-aspartate receptor-deficient mouse cortical neuronal cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

regulation of synaptic plasticity

5 references

10 August 2016

9 May 2019

The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Inducible and reversible NR1 knockout reveals crucial role of the NMDA receptor in preserving remote memories in the brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Impaired hippocampal representation of space in CA1-specific NMDAR1 knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Hippocampal CA1-region-restricted knockout of NMDAR1 gene disrupts synaptic plasticity, place fields, and spatial learning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

transport

1 reference

10 August 2016

cerebral cortex development

3 references

10 August 2016

9 May 2019

Absence of Whisker-related pattern formation in mice with NMDA receptors lacking coincidence detection properties and calcium signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Cortex-restricted disruption of NMDAR1 impairs neuronal patterns in the barrel cortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

olfactory learning

3 references

10 August 2016

9 May 2019

Enrichment induces structural changes and recovery from nonspatial memory deficits in CA1 NMDAR1-knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

CA1-specific N-methyl-D-aspartate receptor knockout mice are deficient in solving a nonspatial transverse patterning task

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

visual learning

7 references

10 August 2016

9 May 2019

The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Impaired sequential egocentric and allocentric memories in forebrain-specific-NMDA receptor knock-out mice during a new task dissociating strategies of navigation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Impaired spatial working memory but spared spatial reference memory following functional loss of NMDA receptors in the dentate gyrus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Hippocampal CA1-region-restricted knockout of NMDAR1 gene disrupts synaptic plasticity, place fields, and spatial learning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Functional consequences of reduction in NMDA receptor glycine affinity in mice carrying targeted point mutations in the glycine binding site

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

A mouse model for the learning and memory deficits associated with neurofibromatosis type I

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

ephrin receptor signaling pathway

1 reference

10 August 2016

ionotropic glutamate receptor signaling pathway

1 reference

10 August 2016

cation transmembrane transport

1 reference

10 August 2016

calcium ion transmembrane transport

1 reference

10 August 2016

ion transmembrane transport

1 reference

10 August 2016

calcium ion transport

1 reference

9 May 2019

Impaired synaptic scaling in mouse hippocampal neurones expressing NMDA receptors with reduced calcium permeability

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

positive regulation of calcium ion transport into cytosol

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

positive regulation of cell death

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

calcium-mediated signaling

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

ionotropic glutamate receptor signaling pathway

regulation of membrane potential

8 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

A conditional deletion of the NR1 subunit of the NMDA receptor in adult spinal cord dorsal horn reduces NMDA currents and injury-induced pain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Impaired spatial working memory but spared spatial reference memory following functional loss of NMDA receptors in the dentate gyrus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Requirement for hippocampal CA3 NMDA receptors in associative memory recall

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Absence of Whisker-related pattern formation in mice with NMDA receptors lacking coincidence detection properties and calcium signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

Impaired synaptic scaling in mouse hippocampal neurones expressing NMDA receptors with reduced calcium permeability

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

rhythmic process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

protein tetramerization

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

regulation of presynaptic membrane potential

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

positive regulation of Schwann cell migration

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

positive regulation of dendritic spine maintenance

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

positive regulation of reactive oxygen species biosynthetic process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

protein localization to postsynaptic membrane

1 reference

9 May 2019

Retention of NMDA receptor NR2 subunits in the lumen of endoplasmic reticulum in targeted NR1 knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

positive regulation of excitatory postsynaptic potential

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438

positive regulation of cysteine-type endopeptidase activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35438