Wikidata

(Q21981588)

English

Frizzled class receptor 8

mammalian protein found in Mus musculus

  • fz-8
  • frizzled-8
  • Fzd8
  • frizzled homolog 8
In more languages
default for all languages
No label defined

No description defined

Statements

molecular function
protein binding
determination method or standard
IPI
11 references
retrieved
14 February 2019
stated in
Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth
GOA
curator
UniProt
UniProt protein ID
Q61091
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method or standard
IPI
retrieved
14 February 2019
stated in
Identification of a PDZ domain containing Golgi protein, GOPC, as an interaction partner of frizzled
GOA
curator
UniProt
UniProt protein ID
Q61091
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method or standard
IPI
retrieved
14 February 2019
stated in
Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method or standard
IPI
retrieved
14 February 2019
stated in
Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method or standard
IPI
retrieved
14 February 2019
stated in
ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method or standard
IPI
retrieved
14 February 2019
stated in
LDL-receptor-related proteins in Wnt signal transduction
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method or standard
IPI
retrieved
14 February 2019
stated in
Structural Studies of Wnts and Identification of an LRP6 Binding Site
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method or standard
IPI
retrieved
14 February 2019
stated in
Identification of a PDZ domain containing Golgi protein, GOPC, as an interaction partner of frizzled
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method or standard
IPI
retrieved
14 February 2019
stated in
Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method or standard
IPI
retrieved
14 February 2019
stated in
SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method or standard
IPI
retrieved
14 February 2019
stated in
IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method or standard
IPI
Wnt-protein binding
determination method or standard
IBA
IPI
5 references
retrieved
14 February 2019
stated in
Reconstitution of a frizzled8.Wnt3a.LRP6 signaling complex reveals multiple Wnt and Dkk1 binding sites on LRP6
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method or standard
IPI
retrieved
14 February 2019
stated in
LDL-receptor-related protein 6 is a receptor for Dickkopf proteins
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method or standard
IPI
retrieved
14 February 2019
stated in
Structural basis of Wnt recognition by Frizzled
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method or standard
IPI
retrieved
14 February 2019
stated in
Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method or standard
IPI
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method or standard
IBA
cell component
biological process
canonical Wnt signaling pathway
determination method or standard
IDA
IGI
IEA
IMP
ISO
7 references
retrieved
24 April 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61091&geneProductId=UniProtKB:Q61091
determination method or standard
ISO
retrieved
24 April 2018
stated in
Wnt proteins induce dishevelled phosphorylation via an LRP5/6- independent mechanism, irrespective of their ability to stabilize beta-catenin
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61091&geneProductId=UniProtKB:Q61091
determination method or standard
IMP
retrieved
24 April 2018
stated in
Truncated mutants of the putative Wnt receptor LRP6/Arrow can stabilize beta-catenin independently of Frizzled proteins
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61091&geneProductId=UniProtKB:Q61091
determination method or standard
IMP
retrieved
24 April 2018
stated in
Wnt signaling is required for thymocyte development and activates Tcf-1 mediated transcription
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61091&geneProductId=UniProtKB:Q61091
determination method or standard
IMP
retrieved
24 April 2018
stated in
Analysis of combinatorial effects of Wnts and Frizzleds on beta-catenin/armadillo stabilization and Dishevelled phosphorylation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61091&geneProductId=UniProtKB:Q61091
determination method or standard
IGI
retrieved
24 April 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61091&geneProductId=UniProtKB:Q61091
determination method or standard
IEA
retrieved
24 April 2018
stated in
Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61091&geneProductId=UniProtKB:Q61091
determination method or standard
IDA
canonical Wnt signaling pathway
determination method or standard
IBA
IDA
IEA
IGI
IMP
ISO
8 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method or standard
ISO
retrieved
14 February 2019
stated in
Truncated mutants of the putative Wnt receptor LRP6/Arrow can stabilize beta-catenin independently of Frizzled proteins
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method or standard
IMP
retrieved
14 February 2019
stated in
Wnt proteins induce dishevelled phosphorylation via an LRP5/6- independent mechanism, irrespective of their ability to stabilize beta-catenin
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method or standard
IMP
retrieved
14 February 2019
stated in
Wnt signaling is required for thymocyte development and activates Tcf-1 mediated transcription
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method or standard
IMP
retrieved
14 February 2019
stated in
Analysis of combinatorial effects of Wnts and Frizzleds on beta-catenin/armadillo stabilization and Dishevelled phosphorylation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method or standard
IGI
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method or standard
IEA
retrieved
14 February 2019
stated in
Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method or standard
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method or standard
IBA

Identifiers

 
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