Wikidata

(Q21499187)

English

Aryl hydrocarbon receptor nuclear translocator-like

mammalian protein found in Mus musculus

  • Arnt3
  • aryl hydrocarbon receptor nuclear translocator-like protein 1
  • Arntl
  • brain and muscle ARNT-like 1
In more languages
default for all languages
No label defined

No description defined

Statements

molecular function
core promoter sequence-specific DNA binding
determination method or standard
IDA
5 references
retrieved
1 January 2018
stated in
A positive feedback loop links circadian clock factor CLOCK-BMAL1 to the basic transcriptional machinery
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTL8&geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
retrieved
1 January 2018
stated in
p53 regulates Period2 expression and the circadian clock
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTL8&geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
retrieved
1 January 2018
stated in
The histone methyltransferase MLL1 permits the oscillation of circadian gene expression
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTL8&geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
retrieved
1 January 2018
stated in
Metastasis-associated protein 1 is an integral component of the circadian molecular machinery
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTL8&geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
retrieved
1 January 2018
stated in
cAMP-response element (CRE)-mediated transcription by activating transcription factor-4 (ATF4) is essential for circadian expression of the Period2 gene
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTL8&geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
protein binding
determination method or standard
IPI
45 references
retrieved
9 May 2019
stated in
Distinct Roles of HDAC3 in the Core Circadian Negative Feedback Loop Are Critical for Clock Function.
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
SIRT1 regulates circadian clock gene expression through PER2 deacetylation
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
Circadian clock feedback cycle through NAMPT-mediated NAD biosynthesis
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
A molecular mechanism for circadian clock negative feedback
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
Circadian proteins CLOCK and BMAL1 in the chromatoid body, a RNA processing granule of male germ cells
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
Histone lysine demethylase JARID1a activates CLOCK-BMAL1 and influences the circadian clock
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
The RelB subunit of NFκB acts as a negative regulator of circadian gene expression
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
The histone methyltransferase MLL1 permits the oscillation of circadian gene expression
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
Preferential inhibition of BMAL2-CLOCK activity by PER2 reemphasizes its negative role and a positive role of BMAL2 in the circadian transcription
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
A positive feedback loop links circadian clock factor CLOCK-BMAL1 to the basic transcriptional machinery
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
Dec1 and Dec2 are regulators of the mammalian molecular clock
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
Magel2, a Prader-Willi syndrome candidate gene, modulates the activities of circadian rhythm proteins in cultured cells
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
Metastasis-associated protein 1 is an integral component of the circadian molecular machinery
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
Identification of two amino acids in the C-terminal domain of mouse CRY2 essential for PER2 interaction
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
A role for the circadian clock protein Per1 in the regulation of aldosterone levels and renal Na retention
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
The mammalian clock component PERIOD2 coordinates circadian output by interaction with nuclear receptors
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
Gene model 129 (Gm129) encodes a novel transcriptional repressor that modulates circadian gene expression
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
Biochemical analysis of the canonical model for the mammalian circadian clock
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
PKCγ participates in food entrainment by regulating BMAL1
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
A novel protein, CHRONO, functions as a core component of the mammalian circadian clock
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
Disruption of CLOCK-BMAL1 transcriptional activity is responsible for aryl hydrocarbon receptor-mediated regulation of Period1 gene
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
The polycomb group protein EZH2 is required for mammalian circadian clock function
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
Deubiquitinating enzyme USP9X regulates cellular clock function by modulating the ubiquitination and degradation of a core circadian protein BMAL1.
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
SRC-2 is an essential coactivator for orchestrating metabolism and circadian rhythm
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
The transcriptional repressor ID2 can interact with the canonical clock components CLOCK and BMAL1 and mediate inhibitory effects on mPer1 expression
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
Cancer/testis antigen PIWIL2 suppresses circadian rhythms by regulating the stability and activity of BMAL1 and CLOCK
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
Signaling mediated by the dopamine D2 receptor potentiates circadian regulation by CLOCK:BMAL1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
Signaling mediated by the dopamine D2 receptor potentiates circadian regulation by CLOCK:BMAL1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
Poly(ADP-ribose) polymerase 1 participates in the phase entrainment of circadian clocks to feeding
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
SIRT1 regulates circadian clock gene expression through PER2 deacetylation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
CLOCK-mediated acetylation of BMAL1 controls circadian function
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
Histone monoubiquitination by Clock-Bmal1 complex marks Per1 and Per2 genes for circadian feedback.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
Machine learning helps identify CHRONO as a circadian clock component
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
The NAD -dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
CRY Drives Cyclic CK2-Mediated BMAL1 Phosphorylation to Control the Mammalian Circadian Clock
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
Identification of two amino acids in the C-terminal domain of mouse CRY2 essential for PER2 interaction
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
Rapid activation of CLOCK by Ca2 -dependent protein kinase C mediates resetting of the mammalian circadian clock
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
JNK regulates the photic response of the mammalian circadian clock
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
Transcriptionally active heterodimer formation of an Arnt-like PAS protein, Arnt3, with HIF-1a, HLF, and clock
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
A novel protein, CHRONO, functions as a core component of the mammalian circadian clock
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
The histone methyltransferase MLL1 permits the oscillation of circadian gene expression
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
Interaction of circadian clock proteins PER2 and CRY with BMAL1 and CLOCK
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
The BMAL1 C terminus regulates the circadian transcription feedback loop.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
Imaging of heme/hemeproteins in nucleus of the living cells expressing heme-binding nuclear receptors
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
retrieved
9 May 2019
stated in
Dynamic circadian protein-protein interaction networks predict temporal organization of cellular functions
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IPI
RNA polymerase II cis-regulatory region sequence-specific DNA binding
determination method or standard
IDA
8 references
retrieved
9 May 2019
stated in
A positive feedback loop links circadian clock factor CLOCK-BMAL1 to the basic transcriptional machinery
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
retrieved
9 May 2019
stated in
p53 regulates Period2 expression and the circadian clock
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
retrieved
9 May 2019
stated in
Gene model 129 (Gm129) encodes a novel transcriptional repressor that modulates circadian gene expression
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
retrieved
9 May 2019
stated in
Metastasis-associated protein 1 is an integral component of the circadian molecular machinery
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
retrieved
9 May 2019
stated in
cAMP-response element (CRE)-mediated transcription by activating transcription factor-4 (ATF4) is essential for circadian expression of the Period2 gene
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
retrieved
9 May 2019
stated in
The histone methyltransferase MLL1 permits the oscillation of circadian gene expression
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
retrieved
9 May 2019
stated in
The RelB subunit of NFκB acts as a negative regulator of circadian gene expression
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
retrieved
9 May 2019
stated in
Expression of the gene for Dec2, a basic helix-loop-helix transcription factor, is regulated by a molecular clock system
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
cell component
nucleus
determination method or standard
IEA
ISO
IDA
8 references
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
ISO
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IEA
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IEA
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IEA
retrieved
9 May 2019
stated in
Distinct Roles of HDAC3 in the Core Circadian Negative Feedback Loop Are Critical for Clock Function.
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
retrieved
9 May 2019
stated in
Magel2, a Prader-Willi syndrome candidate gene, modulates the activities of circadian rhythm proteins in cultured cells
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
retrieved
9 May 2019
stated in
The transcriptional repressor ID2 can interact with the canonical clock components CLOCK and BMAL1 and mediate inhibitory effects on mPer1 expression
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
retrieved
9 May 2019
stated in
BMAL1-dependent circadian oscillation of nuclear CLOCK: posttranslational events induced by dimerization of transcriptional activators of the mammalian clock system
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
biological process
circadian rhythm
determination method or standard
IMP
IDA
IEP
TAS
10 references
retrieved
1 January 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTL8&geneProductId=UniProtKB:Q9WTL8
determination method or standard
TAS
retrieved
1 January 2018
stated in
Mop3 is an essential component of the master circadian pacemaker in mammals
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTL8&geneProductId=UniProtKB:Q9WTL8
determination method or standard
IMP
retrieved
1 January 2018
stated in
LARK activates posttranscriptional expression of an essential mammalian clock protein, PERIOD1.
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTL8&geneProductId=UniProtKB:Q9WTL8
determination method or standard
IMP
retrieved
1 January 2018
stated in
Histone acetyltransferase-dependent chromatin remodeling and the vascular clock
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTL8&geneProductId=UniProtKB:Q9WTL8
determination method or standard
IEP
retrieved
1 January 2018
stated in
A role for Id2 in regulating photic entrainment of the mammalian circadian system
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTL8&geneProductId=UniProtKB:Q9WTL8
determination method or standard
IEP
retrieved
1 January 2018
stated in
ID2 (inhibitor of DNA binding 2) is a rhythmically expressed transcriptional repressor required for circadian clock output in mouse liver
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTL8&geneProductId=UniProtKB:Q9WTL8
determination method or standard
IEP
retrieved
1 January 2018
stated in
The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTL8&geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
retrieved
1 January 2018
stated in
Altered patterns of sleep and behavioral adaptability in NPAS2-deficient mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTL8&geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
retrieved
1 January 2018
stated in
Prokineticin 2 transmits the behavioural circadian rhythm of the suprachiasmatic nucleus
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTL8&geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
retrieved
1 January 2018
stated in
BMAL1-dependent circadian oscillation of nuclear CLOCK: posttranslational events induced by dimerization of transcriptional activators of the mammalian clock system
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTL8&geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
circadian regulation of gene expression
determination method or standard
IDA
IEA
IMP
ISO
9 references
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
ISO
retrieved
9 May 2019
stated in
The clock gene, brain and muscle Arnt-like 1, regulates adipogenesis via Wnt signaling pathway
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IMP
retrieved
9 May 2019
stated in
Circadian clock feedback cycle through NAMPT-mediated NAD biosynthesis
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IMP
retrieved
9 May 2019
stated in
Circadian rhythm transcription factor CLOCK regulates the transcriptional activity of the glucocorticoid receptor by acetylating its hinge region lysine cluster: potential physiological implications
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IMP
retrieved
9 May 2019
stated in
Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IMP
retrieved
9 May 2019
stated in
Brain and muscle Arnt-like 1 is a key regulator of myogenesis
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IMP
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IEA
retrieved
9 May 2019
stated in
A novel protein, CHRONO, functions as a core component of the mammalian circadian clock
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
retrieved
9 May 2019
stated in
Crystal Structure of the Heterodimeric CLOCK:BMAL1 Transcriptional Activator Complex
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
positive regulation of transcription, DNA-templated
determination method or standard
IDA
IEA
IMP
ISO
14 references
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
ISO
retrieved
9 May 2019
stated in
CLOCK regulates circadian rhythms of hepatic glycogen synthesis through transcriptional activation of Gys2
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IMP
retrieved
9 May 2019
stated in
BMAL1-dependent regulation of the mTOR signaling pathway delays aging
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IMP
retrieved
9 May 2019
stated in
Brain and muscle Arnt-like 1 is a key regulator of myogenesis
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IMP
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IEA
retrieved
9 May 2019
stated in
Preferential inhibition of BMAL2-CLOCK activity by PER2 reemphasizes its negative role and a positive role of BMAL2 in the circadian transcription
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
retrieved
9 May 2019
stated in
Circadian clock feedback cycle through NAMPT-mediated NAD biosynthesis
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
retrieved
9 May 2019
stated in
Dec1 and Dec2 are regulators of the mammalian molecular clock
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
retrieved
9 May 2019
stated in
Evidence for an overlapping role of CLOCK and NPAS2 transcription factors in liver circadian oscillators
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
retrieved
9 May 2019
stated in
Metastasis-associated protein 1 is an integral component of the circadian molecular machinery
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
retrieved
9 May 2019
stated in
cAMP-response element (CRE)-mediated transcription by activating transcription factor-4 (ATF4) is essential for circadian expression of the Period2 gene
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
retrieved
9 May 2019
stated in
Transcriptional programming of lipid and amino acid metabolism by the skeletal muscle circadian clock
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
retrieved
9 May 2019
stated in
Circadian rhythm of contrast sensitivity is regulated by a dopamine-neuronal PAS-domain protein 2-adenylyl cyclase 1 signaling pathway in retinal ganglion cells
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
retrieved
9 May 2019
stated in
A novel protein, CHRONO, functions as a core component of the mammalian circadian clock
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
positive regulation of transcription by RNA polymerase II
determination method or standard
IDA
IEA
IGI
ISO
7 references
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
ISO
retrieved
9 May 2019
stated in
Signaling mediated by the dopamine D2 receptor potentiates circadian regulation by CLOCK:BMAL1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IGI
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IEA
retrieved
9 May 2019
stated in
A role for Id2 in regulating photic entrainment of the mammalian circadian system
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
retrieved
9 May 2019
stated in
Expression of the gene for Dec2, a basic helix-loop-helix transcription factor, is regulated by a molecular clock system
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
retrieved
9 May 2019
stated in
A novel autofeedback loop of Dec1 transcription involved in circadian rhythm regulation
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
retrieved
9 May 2019
stated in
DNA binding, but not interaction with Bmal1, is responsible for DEC1-mediated transcription regulation of the circadian gene mPer1
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
circadian rhythm
determination method or standard
IDA
IEP
IMP
9 references
retrieved
9 May 2019
stated in
Mop3 is an essential component of the master circadian pacemaker in mammals
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IMP
retrieved
9 May 2019
stated in
LARK activates posttranscriptional expression of an essential mammalian clock protein, PERIOD1.
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IMP
retrieved
9 May 2019
stated in
Histone acetyltransferase-dependent chromatin remodeling and the vascular clock
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IEP
retrieved
9 May 2019
stated in
ID2 (inhibitor of DNA binding 2) is a rhythmically expressed transcriptional repressor required for circadian clock output in mouse liver
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IEP
retrieved
9 May 2019
stated in
A role for Id2 in regulating photic entrainment of the mammalian circadian system
GOA
curator
UniProt
UniProt protein ID
Q9WTL8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IEP
retrieved
9 May 2019
stated in
The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
retrieved
9 May 2019
stated in
Prokineticin 2 transmits the behavioural circadian rhythm of the suprachiasmatic nucleus
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
retrieved
9 May 2019
stated in
Altered patterns of sleep and behavioral adaptability in NPAS2-deficient mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA
retrieved
9 May 2019
stated in
BMAL1-dependent circadian oscillation of nuclear CLOCK: posttranslational events induced by dimerization of transcriptional activators of the mammalian clock system
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTL8
determination method or standard
IDA

Identifiers

RefSeq protein ID
 
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                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q21499187&oldid=2023184908"