(Q21171805)

English

NLR family pyrin domain containing 1

mammalian protein found in Homo sapiens

death effector filament-forming Ced-4-like apoptosis protein
nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 1
NACHT, leucine rich repeat and PYD (pyrin domain) containing 1
caspase recruitment domain protein 7
caspase recruitment domain-containing protein 7
NACHT, LRR and PYD containing protein 1
nucleotide-binding domain and caspase recruitment domain
NACHT, leucine rich repeat and PYD containing 1
NACHT, LRR and PYD domains-containing protein 1
NLRP1

In more languages

default for all languages

No label defined

No description defined

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

1 December 2016

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein domain specific binding

determination method or standard

1 reference

8 April 2019

The estrogen-responsive B box protein: a novel enhancer of interleukin-1beta secretion

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C000

determination method or standard

nucleotide binding

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C000

determination method or standard

cysteine-type endopeptidase activator activity involved in apoptotic process

determination method or standard

1 reference

8 April 2019

Molecular cloning and characterization of DEFCAP-L and -S, two isoforms of a novel member of the mammalian Ced-4 family of apoptosis proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C000

determination method or standard

determination method or standard

1 reference

8 April 2019

Molecular cloning and characterization of DEFCAP-L and -S, two isoforms of a novel member of the mammalian Ced-4 family of apoptosis proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C000

determination method or standard

protein binding

determination method or standard

7 references

8 April 2019

Novel role of PKR in inflammasome activation and HMGB1 release

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C000

determination method or standard

8 April 2019

CLAN, a novel human CED-4-like gene

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C000

determination method or standard

8 April 2019

Mechanism of Bcl-2 and Bcl-X(L) inhibition of NLRP1 inflammasome: loop domain-dependent suppression of ATP binding and oligomerization

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C000

determination method or standard

8 April 2019

A NOD2-NALP1 complex mediates caspase-1-dependent IL-1beta secretion in response to Bacillus anthracis infection and muramyl dipeptide

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C000

determination method or standard

8 April 2019

Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C000

determination method or standard

8 April 2019

Heterotypic interactions among NACHT domains: implications for regulation of innate immune responses

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C000

determination method or standard

8 April 2019

Evaluation of Nod-like receptor (NLR) effector domain interactions

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C000

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C000

determination method or standard

inflammasome complex

determination method or standard

1 reference

16 July 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9C000&geneProductId=UniProtKB:Q9C000

determination method or standard

intracellular anatomical structure

determination method or standard

1 reference

10 September 2018

Molecular cloning and characterization of DEFCAP-L and -S, two isoforms of a novel member of the mammalian Ced-4 family of apoptosis proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9C000&geneProductId=UniProtKB:Q9C000

determination method or standard

determination method or standard

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C000

determination method or standard

determination method or standard

biological process

neuron apoptotic process

determination method or standard

1 reference

8 April 2019

Expression of NALP1 in cerebellar granule neurons stimulates apoptosis

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C000

determination method or standard

regulation of apoptotic process

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C000

determination method or standard

activation of cysteine-type endopeptidase activity involved in apoptotic process

determination method or standard

response to muramyl dipeptide

determination method or standard

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C000

determination method or standard

apoptotic process

determination method or standard

1 reference

8 April 2019

Molecular cloning and characterization of DEFCAP-L and -S, two isoforms of a novel member of the mammalian Ced-4 family of apoptosis proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C000

determination method or standard

defense response to bacterium

determination method or standard

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C000

determination method or standard

regulation of inflammatory response

determination method or standard

1 reference

8 April 2019

Expression of NALP1 in cerebellar granule neurons stimulates apoptosis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C000

determination method or standard

immune system process

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C000

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C000

determination method or standard

NLRP1 inflammasome complex assembly

determination method or standard

1 reference

8 April 2019

Germline NLRP1 Mutations Cause Skin Inflammatory and Cancer Susceptibility Syndromes via Inflammasome Activation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C000

determination method or standard

activation of cysteine-type endopeptidase activity involved in apoptotic process

determination method or standard

3 references

8 April 2019

Molecular cloning and characterization of DEFCAP-L and -S, two isoforms of a novel member of the mammalian Ced-4 family of apoptosis proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C000

determination method or standard

8 April 2019

Expression of NALP1 in cerebellar granule neurons stimulates apoptosis

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C000

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C000

determination method or standard

positive regulation of cysteine-type endopeptidase activity involved in apoptotic process

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C000

determination method or standard

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000262467

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000262467

ENSP00000269280

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000269280

ENSP00000324366

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000324366

ENSP00000346390

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000346390

ENSP00000442029

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000442029

ENSP00000460216

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000460216

ENSP00000460475

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000460475

ENSP00000478516

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000478516

ENSP00000483359

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000483359

ENSP00000484692

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000484692

ENSP00000458303

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000458303

ENSP00000459661

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000459661

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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