(Q21135800)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O43508

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Tumour necrosis factor domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

13 November 2019

protein binding

3 references

8 April 2019

Identification of an angiogenic factor that when mutated causes susceptibility to Klippel-Trenaunay syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43508

8 April 2019

Structure of the extracellular domains of human and Xenopus Fn14: implications in the evolution of TWEAK and Fn14 interactions

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43508

8 April 2019

TWEAK Negatively Regulates Human Dicer.

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43508

tumor necrosis factor receptor binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43508

1 reference

8 April 2019

signaling receptor binding

1 reference

8 April 2019

Identification of a ligand for the death-domain-containing receptor Apo3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43508

cytokine activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43508

1 reference

8 April 2019

integral component of membrane

cell component

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43508

1 reference

8 April 2019

integral component of plasma membrane

1 reference

8 April 2019

Identification of a ligand for the death-domain-containing receptor Apo3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43508

extracellular region

perinuclear region of cytoplasm

1 reference

8 April 2019

Identification of an angiogenic factor that when mutated causes susceptibility to Klippel-Trenaunay syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43508

extracellular space

extracellular space

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43508

1 reference

8 April 2019

biological process

cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43508

1 reference

8 April 2019

positive regulation of endothelial cell proliferation

1 reference

8 April 2019

Identification of an angiogenic factor that when mutated causes susceptibility to Klippel-Trenaunay syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43508

positive regulation of protein catabolic process

1 reference

8 April 2019

Targeted cardiac overexpression of A20 improves left ventricular performance and reduces compensatory hypertrophy after myocardial infarction

GOA

curator

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43508

extrinsic apoptotic signaling pathway

Ensembl genome database project

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43508

tumor necrosis factor-mediated signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43508

1 reference

8 April 2019

positive regulation of angiogenesis

1 reference

8 April 2019

Identification of an angiogenic factor that when mutated causes susceptibility to Klippel-Trenaunay syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43508

multicellular organism development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43508

1 reference

8 April 2019

angiogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43508

1 reference

8 April 2019

immune response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43508

1 reference

8 April 2019

apoptotic signaling pathway

1 reference

24 April 2018

TWEAK Induces Apoptosis through a Death-signaling Complex Comprising Receptor-interacting Protein 1 (RIP1), Fas-associated Death Domain (FADD), and Caspase-8

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43508&geneProductId=UniProtKB:O43508

positive regulation of extrinsic apoptotic signaling pathway

1 reference

8 April 2019

TWEAK Induces Apoptosis through a Death-signaling Complex Comprising Receptor-interacting Protein 1 (RIP1), Fas-associated Death Domain (FADD), and Caspase-8

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43508

endothelial cell migration

1 reference

8 April 2019

Identification of an angiogenic factor that when mutated causes susceptibility to Klippel-Trenaunay syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43508

signal transduction

1 reference

8 April 2019

Identification of a ligand for the death-domain-containing receptor Apo3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43508

regulation of signaling receptor activity

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43508

Tumour necrosis factor domain

has part(s)

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O43508

Identifiers

MeSH descriptor ID

D000074049

subject named as

Cytokine TWEAK

0 references

MeSH tree code

D12.644.276.374.750.155

0 references

D12.776.467.374.750.155

0 references

0 references

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

21 March 2016

language of work or name

1 reference

inferred by common MeSH mappings on source and on Wikidata

UMLS 2023