Wikidata

(Q21122112)

English

Alanine--glyoxylate and serine--pyruvate aminotransferase

mammalian protein found in Homo sapiens

  • AGXT
  • alanine-glyoxylate aminotransferase
  • hepatic peroxisomal alanine:glyoxylate aminotransferase
  • L-alanine: glyoxylate aminotransferase 1
  • serine--pyruvate aminotransferase
  • AGT
  • 2.6.1.44
  • Alanine--glyoxylate aminotransferase
In more languages
default for all languages
No label defined

No description defined

Statements

molecular function
alanine-glyoxylate transaminase activity
determination method or standard
IDA
IEA
TAS
8 references
retrieved
24 April 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P21549&geneProductId=UniProtKB:P21549
determination method or standard
TAS
retrieved
24 April 2018
stated in
Human peroxisomal L-alanine: glyoxylate aminotransferase. Evolutionary loss of a mitochondrial targeting signal by point mutation of the initiation codon
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P21549&geneProductId=UniProtKB:P21549
determination method or standard
TAS
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P21549
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P21549&geneProductId=UniProtKB:P21549
determination method or standard
IEA
retrieved
24 April 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P21549&geneProductId=UniProtKB:P21549
determination method or standard
IEA
retrieved
24 April 2018
stated in
Human wild-type alanine:glyoxylate aminotransferase and its naturally occurring G82E variant: functional properties and physiological implications
GOA
curator
UniProt
UniProt protein ID
P21549
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P21549&geneProductId=UniProtKB:P21549
determination method or standard
IDA
retrieved
24 April 2018
stated in
The N-terminal extension is essential for the formation of the active dimeric structure of liver peroxisomal alanine:glyoxylate aminotransferase
GOA
curator
UniProt
UniProt protein ID
P21549
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P21549&geneProductId=UniProtKB:P21549
determination method or standard
IDA
retrieved
24 April 2018
stated in
Consequences of missense mutations for dimerization and turnover of alanine:glyoxylate aminotransferase: study of a spectrum of mutations
GOA
curator
UniProt
UniProt protein ID
P21549
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P21549&geneProductId=UniProtKB:P21549
determination method or standard
IDA
retrieved
24 April 2018
stated in
Reactions of human liver peroxisomal alanine:glyoxylate aminotransferase with beta-chloro-L-alanine and L-cysteine: spectroscopic and kinetic analysis
GOA
curator
UniProt
UniProt protein ID
P21549
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P21549&geneProductId=UniProtKB:P21549
determination method or standard
IDA
alanine-glyoxylate transaminase activity
determination method or standard
IBA
IDA
IEA
TAS
8 references
retrieved
8 April 2019
stated in
Human peroxisomal L-alanine: glyoxylate aminotransferase. Evolutionary loss of a mitochondrial targeting signal by point mutation of the initiation codon
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21549
determination method or standard
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P21549
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21549
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21549
determination method or standard
IEA
retrieved
8 April 2019
stated in
The N-terminal extension is essential for the formation of the active dimeric structure of liver peroxisomal alanine:glyoxylate aminotransferase
GOA
curator
UniProt
UniProt protein ID
P21549
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21549
determination method or standard
IDA
retrieved
8 April 2019
stated in
Consequences of missense mutations for dimerization and turnover of alanine:glyoxylate aminotransferase: study of a spectrum of mutations
GOA
curator
UniProt
UniProt protein ID
P21549
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21549
determination method or standard
IDA
retrieved
8 April 2019
stated in
Reactions of human liver peroxisomal alanine:glyoxylate aminotransferase with beta-chloro-L-alanine and L-cysteine: spectroscopic and kinetic analysis
GOA
curator
UniProt
UniProt protein ID
P21549
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21549
determination method or standard
IDA
retrieved
8 April 2019
stated in
Human wild-type alanine:glyoxylate aminotransferase and its naturally occurring G82E variant: functional properties and physiological implications
GOA
curator
UniProt
UniProt protein ID
P21549
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21549
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21549
determination method or standard
IBA
cell component
peroxisome
determination method or standard
IDA
IEA
6 references
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P21549
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P21549&geneProductId=UniProtKB:P21549
determination method or standard
IEA
retrieved
24 April 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P21549&geneProductId=UniProtKB:P21549
determination method or standard
IEA
retrieved
24 April 2018
stated in
Immunocytochemical localization of peroxisomal proteins in human liver and kidney
GOA
curator
UniProt
UniProt protein ID
P21549
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P21549&geneProductId=UniProtKB:P21549
determination method or standard
IDA
retrieved
24 April 2018
stated in
Peroxisomal alanine:glyoxylate aminotransferase deficiency in primary hyperoxaluria type I
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P21549&geneProductId=UniProtKB:P21549
determination method or standard
IDA
retrieved
24 April 2018
stated in
Identification of mutations associated with peroxisome-to-mitochondrion mistargeting of alanine/glyoxylate aminotransferase in primary hyperoxaluria type 1
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P21549&geneProductId=UniProtKB:P21549
determination method or standard
IDA
retrieved
24 April 2018
stated in
Evolution of alanine:glyoxylate aminotransferase 1 peroxisomal and mitochondrial targeting. A survey of its subcellular distribution in the livers of various representatives of the classes Mammalia, Aves and Amphibia
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P21549&geneProductId=UniProtKB:P21549
determination method or standard
IDA
peroxisome
determination method or standard
IBA
IDA
IEA
7 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P21549
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21549
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21549
determination method or standard
IEA
retrieved
8 April 2019
stated in
Immunocytochemical localization of peroxisomal proteins in human liver and kidney
GOA
curator
UniProt
UniProt protein ID
P21549
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21549
determination method or standard
IDA
retrieved
8 April 2019
stated in
Evolution of alanine:glyoxylate aminotransferase 1 peroxisomal and mitochondrial targeting. A survey of its subcellular distribution in the livers of various representatives of the classes Mammalia, Aves and Amphibia
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21549
determination method or standard
IDA
retrieved
8 April 2019
stated in
Identification of mutations associated with peroxisome-to-mitochondrion mistargeting of alanine/glyoxylate aminotransferase in primary hyperoxaluria type 1
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21549
determination method or standard
IDA
retrieved
8 April 2019
stated in
Peroxisomal alanine:glyoxylate aminotransferase deficiency in primary hyperoxaluria type I
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21549
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21549
determination method or standard
IBA
biological process

Identifiers

 
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