Wikidata

(Q21116442)

English

Absent in melanoma 2

mammalian protein found in Homo sapiens

  • AIM2
  • interferon-inducible protein AIM2
In more languages
default for all languages
No label defined

No description defined

Statements

molecular function
protein binding
determination method or standard
IPI
7 references
retrieved
9 May 2019
stated in
The PYRIN domain-only protein POP3 inhibits ALR inflammasomes and regulates responses to infection with DNA viruses
GOA
curator
UniProt
UniProt protein ID
O14862
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14862
determination method or standard
IPI
retrieved
9 May 2019
stated in
Novel role of PKR in inflammasome activation and HMGB1 release
GOA
curator
UniProt
UniProt protein ID
O14862
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14862
determination method or standard
IPI
retrieved
9 May 2019
stated in
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14862
determination method or standard
IPI
retrieved
9 May 2019
stated in
Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14862
determination method or standard
IPI
retrieved
9 May 2019
stated in
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14862
determination method or standard
IPI
retrieved
9 May 2019
stated in
Human cytomegalovirus tegument protein pUL83 inhibits IFI16-mediated DNA sensing for immune evasion
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14862
determination method or standard
IPI
retrieved
9 May 2019
stated in
Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14862
determination method or standard
IPI
cell component
biological process
activation of innate immune response
determination method or standard
IBA
IDA
IEA
6 references
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14862
determination method or standard
IEA
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14862
determination method or standard
IEA
retrieved
9 May 2019
stated in
An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
GOA
curator
UniProt
UniProt protein ID
O14862
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14862
determination method or standard
IDA
retrieved
9 May 2019
stated in
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
GOA
curator
UniProt
UniProt protein ID
O14862
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14862
determination method or standard
IDA
retrieved
9 May 2019
stated in
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
GOA
curator
UniProt
UniProt protein ID
O14862
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14862
determination method or standard
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14862
determination method or standard
IBA

Identifiers

 
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