Wikidata

(Q21111132)

English

SH3 domain containing kinase binding protein 1

mammalian protein found in Homo sapiens

  • SH3 domain-containing kinase-binding protein 1
  • c-Cbl-interacting protein
  • src-related kinase binding protein-1
  • CD2BP3
  • cbl-interacting protein of 85 kDa
  • CD2-binding protein 3
  • SH3KBP1
  • human Src family kinase-binding protein 1
  • SH3-domain kinase binding protein 1
  • migration-inducing gene 18
  • HSB-1
  • Src family kinase-binding protein 1
In more languages
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No label defined

No description defined

Statements

molecular function
protein binding
determination method or standard
IPI
23 references
retrieved
9 May 2019
stated in
Differential requirements for Alix and ESCRT-III in cytokinesis and HIV-1 release
GOA
curator
UniProt
UniProt protein ID
Q96B97
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B97
determination method or standard
IPI
retrieved
9 May 2019
stated in
Phosphorylation of human tristetraprolin in response to its interaction with the Cbl interacting protein CIN85
GOA
curator
UniProt
UniProt protein ID
Q96B97
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B97
determination method or standard
IPI
retrieved
9 May 2019
stated in
Alternate binding modes for a ubiquitin-SH3 domain interaction studied by NMR spectroscopy
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B97
determination method or standard
IPI
retrieved
9 May 2019
stated in
Cbl escapes Cdc42-mediated inhibition by downregulation of the adaptor molecule betaPix
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B97
determination method or standard
IPI
retrieved
9 May 2019
stated in
A Dyn2-CIN85 complex mediates degradative traffic of the EGFR by regulation of late endosomal budding
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B97
determination method or standard
IPI
retrieved
9 May 2019
stated in
Next-generation sequencing to generate interactome datasets
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B97
determination method or standard
IPI
retrieved
9 May 2019
stated in
Cloning and characterization of a novel adaptor protein, CIN85, that interacts with c-Cbl
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B97
determination method or standard
IPI
retrieved
9 May 2019
stated in
CIN85 regulates dopamine receptor endocytosis and governs behaviour in mice
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B97
determination method or standard
IPI
retrieved
9 May 2019
stated in
CIN85 is localized at synapses and forms a complex with S-SCAM via dendrin
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B97
determination method or standard
IPI
retrieved
9 May 2019
stated in
Multimeric and differential binding of CIN85/CD2AP with two atypical proline-rich sequences from CD2 and Cbl-b*
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B97
determination method or standard
IPI
retrieved
9 May 2019
stated in
Sprouty2 acts at the Cbl/CIN85 interface to inhibit epidermal growth factor receptor downregulation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B97
determination method or standard
IPI
retrieved
9 May 2019
stated in
Rho mediates endocytosis of epidermal growth factor receptor through phosphorylation of endophilin A1 by Rho-kinase
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B97
determination method or standard
IPI
retrieved
9 May 2019
stated in
Dab1 stabilizes its interaction with Cin85 by suppressing Cin85 phosphorylation at serine 587
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B97
determination method or standard
IPI
retrieved
9 May 2019
stated in
CIN85 associates with multiple effectors controlling intracellular trafficking of epidermal growth factor receptors
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B97
determination method or standard
IPI
retrieved
9 May 2019
stated in
Interactions between the three CIN85 SH3 domains and ubiquitin: implications for CIN85 ubiquitination
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B97
determination method or standard
IPI
retrieved
9 May 2019
stated in
A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B97
determination method or standard
IPI
retrieved
9 May 2019
stated in
Abl-SH3 binding protein 2, 3BP2, interacts with CIN85 and HIP-55
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B97
determination method or standard
IPI
retrieved
9 May 2019
stated in
Novel insights into the mechanisms of CIN85 SH3 domains binding to Cbl proteins: solution-based investigations and in vivo implications
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B97
determination method or standard
IPI
retrieved
9 May 2019
stated in
CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B97
determination method or standard
IPI
retrieved
9 May 2019
stated in
CIN85 regulates the ability of MEKK4 to activate the p38 MAP kinase pathway
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B97
determination method or standard
IPI
retrieved
9 May 2019
stated in
CIN85, a Cbl-interacting protein, is a component of AMAP1-mediated breast cancer invasion machinery
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B97
determination method or standard
IPI
retrieved
9 May 2019
stated in
A directed protein interaction network for investigating intracellular signal transduction
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B97
determination method or standard
IPI
retrieved
9 May 2019
stated in
Dab2 links CIN85 with clathrin-mediated receptor internalization
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B97
determination method or standard
IPI
cell component
biological process

Identifiers

RefSeq protein ID
 
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