(Q21105452)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9P2Y5

UV radiation resistance protein/autophagy-related protein 14

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9P2Y5

C2 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

protein binding

20 references

9 May 2019

Beclin1 antagonizes LAPTM4B-mediated EGFR overactivation in gastric cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

9 May 2019

Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

9 May 2019

Pacer Mediates the Function of Class III PI3K and HOPS Complexes in Autophagosome Maturation by Engaging Stx17.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

9 May 2019

Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

9 May 2019

Receptor signaling lymphocyte-activation molecule family 1 (Slamf1) regulates membrane fusion and NADPH oxidase 2 (NOX2) activity by recruiting a Beclin-1/Vps34/ultraviolet radiation resistance-associated gene (UVRAG) complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

9 May 2019

UV irradiation resistance‐associated gene suppresses apoptosis by interfering with BAX activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

9 May 2019

Architecture and dynamics of the autophagic phosphatidylinositol 3-kinase complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

9 May 2019

PtdIns(3)P-bound UVRAG coordinates Golgi-ER retrograde and Atg9 transport by differential interactions with the ER tether and the beclin 1 complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

9 May 2019

Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

9 May 2019

NRBF2 regulates autophagy and prevents liver injury by modulating Atg14L-linked phosphatidylinositol-3 kinase III activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

9 May 2019

The RUN domain of rubicon is important for hVps34 binding, lipid kinase inhibition, and autophagy suppression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

9 May 2019

Network organization of the human autophagy system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

9 May 2019

The HOPS complex mediates autophagosome-lysosome fusion through interaction with syntaxin 17

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

9 May 2019

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

9 May 2019

NRBF2 regulates macroautophagy as a component of Vps34 Complex I

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

9 May 2019

EGFR-mediated Beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

9 May 2019

Inhibition of autophagy by TAB2 and TAB3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

9 May 2019

Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

9 May 2019

Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

9 May 2019

Genome-wide siRNA screen reveals amino acid starvation-induced autophagy requires SCOC and WAC

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

cell component

cytoplasm

1 reference

9 May 2019

Molecular cloning of a novel human gene encoding a 63-kDa protein and its sublocalization within the 11q13 locus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

HOPS complex

1 reference

8 April 2019

The role of ESCRT proteins in fusion events involving lysosomes, endosomes and autophagosomes

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

endosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

1 reference

9 May 2019

centrosome

1 reference

9 May 2019

A dual role for UVRAG in maintaining chromosomal stability independent of autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

chromosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

1 reference

9 May 2019

phagocytic vesicle

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

DNA-dependent protein kinase complex

1 reference

9 May 2019

A dual role for UVRAG in maintaining chromosomal stability independent of autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

chromosome, centromeric region

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

1 reference

9 May 2019

protein-containing complex

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

autophagosome membrane

1 reference

9 May 2019

Pacer Mediates the Function of Class III PI3K and HOPS Complexes in Autophagosome Maturation by Engaging Stx17.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

autophagosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

1 reference

9 May 2019

cytoplasmic vesicle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

1 reference

9 May 2019

double-strand break repair via classical nonhomologous end joining

biological process

1 reference

9 May 2019

A dual role for UVRAG in maintaining chromosomal stability independent of autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

regulation of cytokinesis

1 reference

9 May 2019

A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

regulation of protein serine/threonine kinase activity

1 reference

9 May 2019

A dual role for UVRAG in maintaining chromosomal stability independent of autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum

1 reference

9 May 2019

PtdIns(3)P-bound UVRAG coordinates Golgi-ER retrograde and Atg9 transport by differential interactions with the ER tether and the beclin 1 complex

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

multivesicular body sorting pathway

1 reference

9 May 2019

The role of ESCRT proteins in fusion events involving lysosomes, endosomes and autophagosomes

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

chromosome segregation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

regulation of vesicle-mediated transport

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9P2Y5&geneProductId=UniProtKB:Q9P2Y5

1 reference

27 March 2018

receptor catabolic process

IBA

1 reference

9 May 2019

A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

cellular response to DNA damage stimulus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

1 reference

9 May 2019

autophagy

1 reference

9 May 2019

PtdIns(3)P-bound UVRAG coordinates Golgi-ER retrograde and Atg9 transport by differential interactions with the ER tether and the beclin 1 complex

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

spindle organization

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

viral entry into host cell

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

maintenance of Golgi location

1 reference

9 May 2019

PtdIns(3)P-bound UVRAG coordinates Golgi-ER retrograde and Atg9 transport by differential interactions with the ER tether and the beclin 1 complex

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

DNA repair

Molecular cloning of a novel human gene encoding a 63-kDa protein and its sublocalization within the 11q13 locus

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

9 May 2019

A dual role for UVRAG in maintaining chromosomal stability independent of autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

positive regulation of autophagosome maturation

1 reference

9 May 2019

The role of ESCRT proteins in fusion events involving lysosomes, endosomes and autophagosomes

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

autophagosome maturation

1 reference

9 May 2019

Pacer Mediates the Function of Class III PI3K and HOPS Complexes in Autophagosome Maturation by Engaging Stx17.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2Y5

1 reference

InterPro Release 71.0