Wikidata

(Q1649375)

English

Fas cell surface death receptor

mammalian protein found in Homo sapiens

  • Fas (TNF receptor superfamily, member 6)
  • FAS
  • FASLG receptor
  • TNF receptor superfamily member 6
  • APO-1 cell surface antigen
  • apoptosis antigen 1
  • CD95 antigen
  • tumor necrosis factor receptor superfamily, member 6
  • Fas AMA
  • Apo-1 antigen
  • apoptosis-mediating surface antigen FAS
  • apoptosis signaling receptor FAS
  • mutant tumor necrosis receptor superfamily member 6
  • tumor necrosis factor receptor superfamily member 6
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Statements

image
Fas receptor.png
3,200 × 2,400; 1.84 MB
0 references
molecular function
protein binding
determination method or standard
IPI
18 references
retrieved
8 April 2019
stated in
Whole-exome-sequencing-based discovery of human FADD deficiency
GOA
curator
UniProt
UniProt protein ID
P25445
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
determination method or standard
IPI
retrieved
8 April 2019
stated in
A death receptor-associated anti-apoptotic protein, BRE, inhibits mitochondrial apoptotic pathway
GOA
curator
UniProt
UniProt protein ID
P25445
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
determination method or standard
IPI
retrieved
8 April 2019
stated in
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
determination method or standard
IPI
retrieved
8 April 2019
stated in
Apoptosis signal-regulating kinase 1 controls the proapoptotic function of death-associated protein (Daxx) in the cytoplasm
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
determination method or standard
IPI
retrieved
8 April 2019
stated in
A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
determination method or standard
IPI
retrieved
8 April 2019
stated in
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
determination method or standard
IPI
retrieved
8 April 2019
stated in
Caveolin-1 mediates Fas-BID signaling in hyperoxia-induced apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
determination method or standard
IPI
retrieved
8 April 2019
stated in
Apoptosis-linked gene 2 binds to the death domain of Fas and dissociates from Fas during Fas-mediated apoptosis in Jurkat cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
determination method or standard
IPI
retrieved
8 April 2019
stated in
Palmitoylation of CD95 facilitates formation of SDS-stable receptor aggregates that initiate apoptosis signaling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
determination method or standard
IPI
retrieved
8 April 2019
stated in
Caspase-8 prevents sustained activation of NF-kappaB in monocytes undergoing macrophagic differentiation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
determination method or standard
IPI
retrieved
8 April 2019
stated in
FAP-1 association with Fas (Apo-1) inhibits Fas expression on the cell surface
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
determination method or standard
IPI
retrieved
8 April 2019
stated in
FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
determination method or standard
IPI
retrieved
8 April 2019
stated in
Modulation of the CD95-induced apoptosis: the role of CD95 N-glycosylation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
determination method or standard
IPI
retrieved
8 April 2019
stated in
Inhibition of Daxx-mediated apoptosis by heat shock protein 27
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
determination method or standard
IPI
retrieved
8 April 2019
stated in
Negative regulation of Fas-mediated apoptosis by FAP-1 in human cancer cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
determination method or standard
IPI
retrieved
8 April 2019
stated in
Yes and PI3K bind CD95 to signal invasion of glioblastoma
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
determination method or standard
IPI
retrieved
8 April 2019
stated in
PMLRARα binds to Fas and suppresses Fas-mediated apoptosis through recruiting c-FLIP in vivo
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
determination method or standard
IPI
retrieved
8 April 2019
stated in
The role of receptor internalization in CD95 signaling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
determination method or standard
IPI
cell component
biological process
Gene Atlas image
PBB GE FAS 204780 s at fs.png
732 × 530; 11 KB
0 references

Identifiers

 
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