Wikipedia

FMNレダクターゼ

FMNレダクターゼ(FMN reductase, SsuE)は、次の化学反応を触媒する酸化還元酵素である。

FMNレダクターゼ
識別子
EC番号 1.5.1.29
CAS登録番号 64295-83-6
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FMNH2 NAD(P) FMN NAD(P)H H

反応式の通り、この酵素の基質はFMNH2とNAD （またはNADP ）、生成物はFMNとNADH（NADPH）とH である。

組織名はFMNH2:NAD(P) oxidoreductaseで、別名にNAD(P)H-FMN reductase, NAD(P)H-dependent FMN reductase, NAD(P)H:FMN oxidoreductase, NAD(P)H:flavin oxidoreductase, NAD(P)H2 dehydrogenase (FMN), NAD(P)H2:FMN oxidoreductase, riboflavin mononucleotide reductase, flavine mononucleotide reductase, riboflavin mononucleotide (reduced nicotinamide adenine dinucleotide (phosphate)) reductase, flavin mononucleotide reductase, riboflavine mononucleotide reductaseがある。

参考文献

編集
  • Duane W, Hastings JW (1975). “Flavin mononucleotide reductase of luminous bacteria”. Mol. Cell. Biochem. 6: 53–64. doi:10.1007/BF01731866. PMID 47604. 
  • Fisher J, Spencer R, Walsh C (1976). “Enzyme-catalyzed redox reactions with the flavin analogues 5-deazariboflavin, 5-deazariboflavin 5'-phosphte, and 5-deazariboflavin 5'-diphosphate, 5' leads to 5'-adenosine ester”. Biochemistry. 15: 1054–64. doi:10.1021/bi00650a016. PMID 3207. 
  • Tu SC, Becvar JE, Hastings JW (1979). “Kinetic studies on the mechanism of bacterial NAD(P)H:flavin oxidoreductase”. Arch. Biochem. Biophys. 193: 110–6. doi:10.1016/0003-9861(79)90013-4. PMID 222213. 
  • Liu M, Lei B, Ding Q, Lee JC, Tu SC (1997). “Vibrio harveyi NADPH:FMN oxidoreductase: preparation and characterization of the apoenzyme and monomer-dimer equilibrium”. Arch. Biochem. Biophys. 337: 89–95. doi:10.1006/abbi.1996.9746. PMID 8990272. 
  • Lei B, Tu SC (1998). “Mechanism of reduced flavin transfer from Vibrio harveyi NADPH-FMN oxidoreductase to luciferase”. Biochemistry. 37: 14623–9. doi:10.1021/bi981841. PMID 9772191. 
  • Tang CK, Jeffers CE, Nichols JC, Tu SC (2001). “Flavin specificity and subunit interaction of Vibrio fischeri general NAD(P)H-flavin oxidoreductase FRG/FRase I”. Arch. Biochem. Biophys. 392: 110–6. doi:10.1006/abbi.2001.2396. PMID 11469801. 
  • Ingelman M, Ramaswamy S, Niviere V, Fontecave M, Eklund H (1999). “Crystal structure of NAD(P)H:flavin oxidoreductase from Escherichia coli”. Biochemistry. 38: 7040–9. doi:10.1021/bi982849m. PMID 10353815. 
  • Eichhorn E, van der Ploeg JR, Leisinger T (1999). “Characterization of a two-component alkanesulfonate monooxygenase from Escherichia coli”. J. Biol. Chem. 274: 26639–46. doi:10.1074/jbc.274.38.26639. PMID 10480865. 
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