Yes, In render properties, Set device to GPU compute.
If it doesn't let you, Go to Edit in the top left, click preferences, click System, then click OptiX and check your graphics card.
Smaples should be no more than 256.
Denoise is enabled.
Set prefilter to "Fast"
Emable use GPU under denoise.
Scrolling down under "Performance" emable "Persistent Data" under "Final Render".