PopVax I hiring actively for our ADME and Toxicology departments.
PopVax is hiring a Junior Scientist or Scientist to work on Toxicology & ADME studies. As our first program moves into the clinic, we are beginning preclinical work on a variety of novel mRNA vaccines and therapeutics in parallel. We are seeking a highly motivated and detail-oriented researcher to plan, coordinate, and supervise ADME (Absorption, Distribution, Metabolism, and Excretion) studies, including biodistribution, and GLP toxicology studies for these novel mRNA vaccine and therapeutic candidates – we expect we will be preparing up to 5 such candidates for IND next year. This is a unique opportunity to operate on the frontier of our understanding of the physiological impact of cutting-edge protein design and nucleic acid modalities. Key responsibilities will include: - Designing in vitro and in vivo toxicology and ADME studies aligning with relevant scientific and regulatory standards, in particular those that apply in India, the United States, Europe, and ICH jurisdictions broadly – this also requires staying current with changes in these guidelines and requirements. - Writing and reviewing complete study protocols for toxicology and ADME studies. - Analyzing toxicokinetic and pharmacokinetic data to assess safety profiles for our vaccine and therapeutic candidates, and preparing detailed reports to communicate these findings to internal and external stakeholders. - Preparing and formatting toxicology and ADME data for IND filings. - Collaborating cross-functionally with R&D, Regulatory Affairs, Quality Control, and Quality Assurance to conduct and document studies. - Instructing, coordinating with, and reviewing the work of Contract Research Organizations (CROs) engaged to execute toxicology and ADME studies. Apply here: https://lnkd.in/dRFwPxPp