ORG-21465
ORG-21465 bụ steroid na-arụ ọrụ na ụbụrụ, nke nwere mmetụta sedative nke sitere na ọrụ ya dị ka modulador allosteric nke GABAA. Ọ dị ka ọgwụ ndị yiri ya dị ka ORG-20599, e mepụtara ya n'otu aka ahụ dị ka ihe na ụdị nke ụwa họrọ site na iji bịa ọzọ ka mma karịa ọgwụ ndị ọzọ dị ka althesin na allopregnanolone, nke n'agbanyeghị ihe ndị dị elu ya n'akụkụ ụfọdụ egosighi na ọ ga-enye uru zuru ezu iji nabata ya na ọgwụ.[1][2]
Chemistry
[dezie | dezie ebe o si]Hụkwa
[dezie | dezie ebe o si]Ntụaka
[dezie | dezie ebe o si]- ↑ (October 1997) "ORG 21465, a new water-soluble steroid hypnotic: more of the same or something different?". British Journal of Anaesthesia 79 (4): 417–9. DOI:10.1093/bja/79.4.417. PMID 9389254.
- ↑ (2008) "Etomidate and other non-barbiturates", Modern Anesthetics, Handbook of Experimental Pharmacology, 267–82. DOI:10.1007/978-3-540-74806-9_13. ISBN 978-3-540-72813-9.