Ciwon Gilbert
| Ciwon Gilbert | |
|---|---|
 | |
Description (en)  | |
| Iri |
bilirubin metabolic disorder (en) cuta |
| Specialty (en) |
hepatology (en) family medicine (en) |
| Genetic association (en) |
UGT1A1 (en) |
| Suna saboda |
Augustin Nicolas Gilbert (mul) da Einar Meulengracht (en) |
| Identifier (en) | |
| ICD-10-CM | E80.4 |
| ICD-10 | E80.4 |
| ICD-9 | 277.4 |
| OMIM | 143500 da 143500 |
| DiseasesDB | 5218 |
| MedlinePlus | 000301 |
| eMedicine | 000301 |
| MeSH | D005878 |
| Disease Ontology ID | DOID:2739 |
Ciwon Gilbert (GS) wani yanayi ne mai laushi da aka gada wanda yawanci ba ya haifar da lahani.[1] Gabaɗaya babu alamun bayyanar.[2] Wani lokaci launin rawaya kaɗan na fata ko fararen idanu na iya faruwa, musamman a lokacin kowace irin rashin lafiya.[2] Da wuya, akwai yuwuwar gajiya, rauni, da ciwon ciki.[2] Sau da yawa ba a lura da shi har zuwa ƙarshen ƙuruciya zuwa farkon girma.[3]
A cikin ciwon Gilbert, hanta ba ta sarrafa bilirubin yadda ya kamata.[2] Ya faru ne saboda maye gurbi a cikin kwayar halittar UGT1A1 wanda ke haifar da raguwar ayyukan bilirubin uridine diphosphate glucuronosyltransferase enzyme.[2][4] Yawanci ana gadonsa a cikin tsarin koma baya na autosomal kuma lokaci-lokaci a cikin mafi girman tsarin da ya danganta da nau'in maye gurbi.[4] Abubuwan jaundice na iya haifar da damuwa kamar motsa jiki, haila, ko rashin ci.[4] Bincike ya dogara ne akan mafi girman matakan bilirubin da ba a haɗa su a cikin jini ba tare da ko dai alamun wasu matsalolin hanta ko rushewar kwayar jini ba.[3][4]
Yawanci ba a buƙatar magani.[2] Idan jaundice yana da mahimmanci, ana iya amfani da phenobarbital.[2] Ciwon Gilbert yana shafar 2 zuwa 7% na mutane.[1] 5 zuwa 15% na mutanen da abin ya shafa suna da tarihin iyali na jaundice.[1] Maza sun fi gano cutar fiye da mata.[2] An fara kwatanta yanayin a cikin 1901 ta Augustin Nicolas Gilbert.[3][5]
Manazarta
[gyara sashe | gyara masomin]- ↑ 1.0 1.1 1.2 Foster, Graham; O'Brien, Alastair (2020). "34. Liver disease". In Feather, Adam; Randall, David; Waterhouse, Mona (eds.). Kumar and Clark's Clinical Medicine (in Turanci) (10th ed.). Elsevier. p. 1272. ISBN 978-0-7020-7870-5.
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 "Gilbert syndrome". GARD (in Turanci). 2016. Archived from the original on 4 August 2017. Retrieved 2 July 2017.
- ↑ 3.0 3.1 3.2 "Gilbert Syndrome". NORD (National Organization for Rare Disorders). 2015. Archived from the original on 20 February 2017. Retrieved 2 July 2017.
- ↑ 4.0 4.1 4.2 4.3 "Gilbert syndrome". Genetics Home Reference (in Turanci). 27 June 2017. Archived from the original on 27 June 2017. Retrieved 2 July 2017.
- ↑ "Whonamedit – dictionary of medical eponyms". www.whonamedit.com (in Turanci). Archived from the original on 18 September 2016. Retrieved 2 July 2017.