CurifyLabs

Izaskun Malo was interviewed on the topic of new technologies in compounding pharmacies. She is in charge of the Malo Manso Pharmacy in Spain and a pioneer for more than 13 years in magistral formulation. Malo got to know our technology through Pharmacie et préparatoire Delpech Paris and in this podcast she speaks about the future of manufacturing personalized medicine. Listen to hear thoughts at Spotify https://lnkd.in/d9ufh3uq

We spoke with our customers, Dr. Marija Tubic Grozdanis (Clinical Pharmacist) and Prof. Dr. Alexandra Russo (Pediatric Oncologist) from University Medical Center Mainz, about the future of personalized medicine in pediatric oncology. "Question: How does automated compounding technology contribute to your work? What benefits have you observed? Prof. Dr. Alexandra Russo: Children often face more challenges than adults in accessing innovative therapies due to a lack of safety data and authorization for pediatric use of new medicines. On average, it takes about 10 years after a drug is approved for adults before it becomes accessible to children. Dr. Marija Tubic Grozdanis: While pharmacies can prepare individualized capsules or suspensions in the prescribed dosage, these extemporaneous formulations often have poor or inconsistent bioavailability, low quality, and low safety. This is typically due to insufficient personnel for handling carcinogenic, mutagenic, and toxic drugs, and the unavailability of necessary starting materials. Prof. Dr. Alexandra Russo: Furthermore, it's challenging for parents and caregivers to administer medication to children in the form of suspensions or capsule contents prepared at home. They must open the capsules under safety conditions, such as masks, gowns and gloves, and mix the powder with juices or food, like yogurt. These mixtures are often rejected or spat out by children. We are missing data on the stability of the medication for example in different pH values of the juices and therefore how much of the dose actually reaches the child. Clearly, there is an urgent need for more customized, safe, child-friendly, and tasty dosage forms, to ensure reliable and safe dosing. Dr. Marija Tubic Grozdanis: By using a validated automated compounding system, we can protect pharmacy and ward personnel from exposure to cytotoxic drugs. Moreover, manufacturing with a validated automated compounding process ensures that formulations have accurate and personalized doses with consistent quality attributes and stability. This process can also save time spent on preparation and cleaning procedures. Read more insights our website and thanks for the interview, Marija Tubic Grozdanis & Alexandra Russo! #futureofmanufacturingpersonalizedmedicine #pediatriconcology

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🌿 Join us at CurifyLabs in our commitment to sustainability! Our Pharma Kit offers on-demand manufacturing, adaptive dosage for intensive care, easy cleanability, and requires fewer excipients. Let's work together towards a greener future in the pharmaceutical industry! 🌱 #Sustainability #Pharmaceutical #Innovation #CurifyLabsSustainability at CurifyLabs - Sustainability CurifyLabs https://hubs.li/Q02DhD2C0

Last week we hosted an event about the future of personalized medicines. Pharmacists and physicians from 12 countries participated in the event over two days. Key take aways: ✔️There is an enormous need for personalized medicine and practical solutions enabling better manufacturing methods are needed. In some countries nurses at the ward are allowed to distribute drugs mixed with food or juice, but pharmacists can’t do the same and are pressed with tougher quality requirements. This leads to situations where nurses are spending time on crushing tablets and mixing them in to for instance juice, without any knowledge on what this does to the physicochemical properties of the drug and dosage form. ✔️ 40 % of participants think that the biggest problem with current compounding manufacturing methods is that quality control is limited. We heard examples of how oral suspension mixes are commonly trusted on the market, although there are problems related to taste, stability and potential for dosing errors. ✔️ Clinicians and pharmacists need to collaborate and drive the change together. In some countries the collaboration between pharmacists and physicians is close and functioning well, whereas in some countries there is not much collaboration. ✔️Especially children are underserved when it comes to registered drugs. Big pharma does not have financial motivation to register drugs in doses which are suitable for children. There are many examples of what this leads to; for instance pregnant mothers mixing harmful drugs at home or no treatment at all. ✔️ Personalization is crucial also for elderly patients, in gender medicine as well as in oncology and veterinary preparations. ✔️ The preparedness for new innovations varies between countries, institutions and even people working at the same institution. Let’s think “how can we make this possible” instead of “this is not possible”. ✔️ Compounding pharmacists play a critical role in managing drug shortages and after the COVID-19 pandemic the preparedness is much better. However more work is needed and compounding pharmacists deserve more credit for the work they do. ✔️ Regulators are positive and there are many examples of this from different countries. Thanks to all participants, together we can change things for the benefit of patients! Psst.. If you think that this looks like an even that you would like to attend in the future, please send us a message at [email protected] and we will make sure to keep you posted. https://hubs.li/Q02C11xq0

Jana Lass & Tartu University Hospital - thank you for being top innovators of personalized medicine!

We did it again! We are proud to announce the renewal of our ISO 13485 certification, reinforcing our commitment to quality, safety, and customer satisfaction. Why ISO 13485 Matters Quality Assurance: Ensures our products meet the highest quality standards. Regulatory Compliance: Facilitates market access and approval processes. Risk Management: Focuses on identifying and mitigating risks throughout the product lifecycle. Customer Satisfaction: Consistently delivers products that exceed customer expectations. The Renewal Journey Internal Audits: Evaluated and improved our quality management system. Training and Development: Kept our team updated with the latest standards and practices. External Audits: Underwent a detailed independent audit to verify compliance. Continuous Improvement: Implemented corrective actions and improvements based on audit findings. Our Future Commitment Renewing our ISO 13485 certification is a continuous process. We are committed to upholding these standards, focusing on quality, safety, and customer satisfaction as we innovate and develop cutting-edge products that make a difference in patients' lives. Thank you to our dedicated team, especially Quality Manager Farnaz Shokraneh, and customers for your support. Together, we will continue to uphold the highest standards and set new benchmarks in the industry. #CurifyLabs #ISO13485 #QualityManagement #Innovation #CustomerSatisfaction #RegulatoryCompliance https://hubs.li/Q02Bx2gK0

Last but definately not least, we're pleased to introduce Mr Fabien Bruno as one of our speakers in Helsinki for Innovators of Personalized Medicine: Fabien Bruno Fabien Bruno is the owner of Pharmacie et préparatoire Delpech Paris, which specializes in magistral preparations and is one of the largest compounding pharmacies in Europe. With a profound expertise in pharmaceutical technologies, Fabien will share innovative strategies that are setting new standards in healthcare treatments. Fabien is especially active in topics related to drug shortages. Welcome to Helsinki, Fabien! #innovatorsofpersonalizedmedicine

Meet the speakers #6: Karim Khoukh Karim KHOUKH (PharmD., MSc. Chemistry) is a pharmacist at Pharmacie et préparatoire Delpech Paris, a French leader of non-sterile compounding. As a formulation expert, Karim develops solutions in personalized medicine. In collaboration with hospitals, he works on finding well-tolerated treatments for children, suffering from rare disease. Karim also works with veterinary hospitals to improve pet compliance, especially in cats. With his background in chemistry, Karim runs the quality control lab of Pharmacie Delpech, performing studies to ensure safety of pharmaceutical compounding. #innovatorsofpersonalizedmedicine

It's time to introduce speaker #5 at our event for Innovators of Personalized Medicines coming up in Helsinki later this week: Petri Bono Petri Bono serves as the Chief Medical Officer and part of the executive team of Terveystalo, the largest healthcare service company in Finland. Prior to Terveystalo he was the Chief Medical Officer at Helsinki University Hospital. In addition, Dr. Bono has held various leadership positions within Helsinki University Hospital, including as the Director and Physician-in-Chief of the Comprehensive Cancer Center. Dr Bono’s own research has been focused in many areas of molecular and immunological oncology. Dr Bono has participated in >50 clinical trials including early phase immuno-oncological trials and published >100 peer reviewed papers in international scientific journals. #innovatorsofpersonalizedmedicine