CLIC6

CLIC6
Identifikatzaileak
Aliasak	CLIC6 (HUGO), CLIC1L, chloride intracellular channel 6
Kanpoko IDak	OMIM: 615321 MGI: 2146607 HomoloGene: 43154 GeneCards: CLIC6 OMA: CLIC6 - orthologs
Genearen kokapena (gizakia)
	Kromosoma: 21 (gizakia)
Amaiera	34.718.227 bp
Genearen kokapena (sagua)
	Kromosoma: 16 (sagua)
Amaiera	92.338.131 bp
RNA adierazpen eredua
	Adierazpen ohikoena
	retinal pigment epithelium ; ; bronchial epithelial cell ; ; nasal epithelium ; ; caput epididymis ; ; palpebral conjunctiva ; ; epithelium of nasopharynx ; ; mucosa of paranasal sinus ; ; pancreatic epithelial cell ; ; olfactory zone of nasal mucosa ; ; pancreatic ductal cell ;
	Adierazpen ohikoena
	Epithelium of choroid plexus ; ; epithelium of stomach ; ; retinal pigment epithelium ; ; olfactory epithelium ; ; gorputz ziliar; ; migratory enteric neural crest cell ; ; epithelium of small intestine ; ; Zaku bitelino; ; left colon ; ; efferent ductule ;
	Erreferentziazko adierazpen datu gehiago
Gene ontologia
Funtzio molekularra	voltage-gated ion channel activity ; glutathione transferase activity ; chloride channel activity ; D2 dopamine receptor binding ; D3 dopamine receptor binding ; D4 dopamine receptor binding ;
Zelularen osagaia	zelula-mintzaren osagai integrala ; zelula mintz ; extracellular exosome ; mintza ; chloride channel complex ; zelula nukleo ; zitoplasma ;
Prozesu biologikoa	regulation of ion transmembrane transport ; chloride transport ; ioi garraioa ; glutathione metabolic process ; chloride transmembrane transport ; garraio ; mintzan zeharreko ioi garraioa ;
	Iturburuak:Amigo / QuickGO
Ortologoak
	54102
	209195
	ENSG00000159212
	ENSMUSG00000022949
	Q96NY7
	Q8BHB9
	NM_053277; NM_001317009
	NM_172469
	NP_001303938; NP_444507
	NP_766057
	Wikidata
Ikusi/Editatu giza genea	Ikusi/Editatu saguaren genea

Kloruroaren kanal intrazelularraren proteina 6 gizakiengan CLIC6 geneak kodetzen duen proteina da^[5].

CLIC6 geneak kloruroaren kanal intrazelularraren familiako proteina bat kodetzen du. Genea 1, 6 eta 21 kromosometan dagoen eskualde handi hirukoiztu baten parte da. Zatiketa alternatiboa eskaintzen duen transkripzio bat deskribatu da ere, baina bere baliagarritasun genetikoa ez da zehaztu^[6].

Elkarrekintzak

CLIC6-ek dopamina D3 errezeptorearekin elkarrekintza duela ikusi da^[7].

Erreferentziak

↑ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000159212 - Ensembl, May 2017
↑ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000022949 – Ensembl, May 2017
↑ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ (Ingelesez) Hattori, M.; Fujiyama, A.; Taylor, T. D.; Watanabe, H.; Yada, T.; Park, H.-S.; Toyoda, A.; Ishii, K. et al.. (2000-05-18). «The DNA sequence of human chromosome 21» Nature 405 (6784): 311–319. doi:10.1038/35012518. ISSN 0028-0836. (Noiz kontsultatua: 2023-02-16).
↑ «CLIC6 chloride intracellular channel 6 [Homo sapiens (human) - Gene - NCBI»] www.ncbi.nlm.nih.gov (Noiz kontsultatua: 2023-02-16).
↑ (Ingelesez) Griffon, Nathalie; Jeanneteau, Freddy; Prieur, Fanny; Diaz, Jorge; Sokoloff, Pierre. (2003-09-10). «CLIC6, a member of the intracellular chloride channel family, interacts with dopamine D2-like receptors» Molecular Brain Research 117 (1): 47–57. doi:10.1016/S0169-328X(03)00283-3. ISSN 0169-328X. (Noiz kontsultatua: 2023-02-16).

Kanpo estekak

Datuak: Q18040930

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000159212 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000022949 – Ensembl, May 2017

[3] Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[5] (Ingelesez) Hattori, M.; Fujiyama, A.; Taylor, T. D.; Watanabe, H.; Yada, T.; Park, H.-S.; Toyoda, A.; Ishii, K. et al.. (2000-05-18). «The DNA sequence of human chromosome 21» Nature 405 (6784): 311–319. doi:10.1038/35012518. ISSN 0028-0836. (Noiz kontsultatua: 2023-02-16).

[6] «CLIC6 chloride intracellular channel 6 [Homo sapiens (human) - Gene - NCBI»] www.ncbi.nlm.nih.gov (Noiz kontsultatua: 2023-02-16).

[7] (Ingelesez) Griffon, Nathalie; Jeanneteau, Freddy; Prieur, Fanny; Diaz, Jorge; Sokoloff, Pierre. (2003-09-10). «CLIC6, a member of the intracellular chloride channel family, interacts with dopamine D2-like receptors» Molecular Brain Research 117 (1): 47–57. doi:10.1016/S0169-328X(03)00283-3. ISSN 0169-328X. (Noiz kontsultatua: 2023-02-16).

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