Glenn Plummer ... Timmy Rawlins (15 episodes, 1994-2007)
Matthew Glave ... Dr. Dale Edson (15 episodes, 1996-2002)
John Cullum ... David Greene (15 episodes, 1997-2000)
Suzanne Carney ... OR Nurse Janet (15 episodes, 1994-2000)
J.P. Hubbell ... EMT Lars Audia (15 episodes, 1997-1999)
Chad McKnight ... Officer Wilson (15 episodes, 1995-2006)
Busy Philipps ... Hope Bobeck / ... (14 episodes, 2006-2007)
Cress Williams ... Officer Reggie Moore (14 episodes, 1998-2008)
Elizabeth Mitchell ... Dr. Kim Legaspi (14 episodes, 2000-2001)
Thandie Newton ... Makemba 'Kem' Likasu (14 episodes, 2003-2009)
Gina Ravera ... Dr. Bettina DeJesus (13 episodes, 2006-2008)
Mariska Hargitay ... Cynthia Hooper (13 episodes, 1997-1998)
Charles Noland ... E-Ray (13 episodes, 1995-1997)
Brendan Patrick Connor ... Reidy (13 episodes, 2006-2009)
Lucy Rodriguez ... Nurse Bjerke (13 episodes, 1996-2003)
John Leguizamo ... Dr. Victor Clemente (12 episodes, 2005-2006)
Mike Genovese ... Officer Al Grabarsky (12 episodes, 1994-2000)
Scott Jaeck ... Dr. Steven Flint (12 episodes, 1994-2002)
Christopher Amitrano ... Officer Hollis (12 episodes, 2006-2009)
Sally Field ... Maggie Wyczenski (12 episodes, 2000-2006)
Michael B. Silver ... Dr. Paul Myers (12 episodes, 1995-2009)
Lisa Vidal ... Sandy Lopez (12 episodes, 2001-2004)
Stuart McLean ... X-Ray Tech / ... (12 episodes, 1998-2004)
Rick Rossovich ... Dr. John 'Tag' Taglieri (11 episodes, 1994-1995)
Malaya Rivera Drew ... Katey Alvaro (11 episodes, 2006-2007)
Steven Christopher Parker ... Harold Zelinsky / ... (11 episodes, 2005-2008)
Emily Rose ... Dr. Tracy Martin (11 episodes, 2008-2009)
Donal Logue ... Chuck Martin (11 episodes, 2003-2005)
Rossif Sutherland ... Lester Kertzenstein (11 episodes, 2003-2004)
Stanley Tucci ... Dr. Kevin Moretti (10 episodes, 2007-2008)
