THAP2

THAP2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2D8R
Identifiers
Aliases	THAP2, THAP domain containing 2
External IDs	OMIM: 612531; MGI: 1914066; HomoloGene: 12039; GeneCards: THAP2; OMA:THAP2 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	71,680,644 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	115,220,348 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; ventricular zone; ; left testis; ; right testis; ; testicle; ; monocyte; ; anterior pituitary; ; appendix; ; right uterine tube; ; gallbladder;
	Top expressed in
	lacrimal gland; ; trigeminal ganglion; ; medial ganglionic eminence; ; tail of embryo; ; genital tubercle; ; ventricular zone; ; transitional epithelium of urinary bladder; ; migratory enteric neural crest cell; ; parotid gland; ; atrioventricular valve;
	More reference expression data
	n/a
Gene ontology
Molecular function	metal ion binding; DNA binding; nucleic acid binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleolus;
Biological process	regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	83591
	66816
	ENSG00000173451
	ENSMUSG00000020137
	Q9H0W7
	Q9D305
	NM_031435
	NM_025780
	NP_113623
	NP_080056
	Wikidata
View/Edit Human	View/Edit Mouse

THAP domain-containing protein 2 is a protein that in humans is encoded by the THAP2 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000173451 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000020137 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Roussigne M, Kossida S, Lavigne AC, Clouaire T, Ecochard V, Glories A, Amalric F, Girard JP (Feb 2003). "The THAP domain: a novel protein motif with similarity to the DNA-binding domain of P element transposase". Trends Biochem Sci. 28 (2): 66–9. doi:10.1016/S0968-0004(02)00013-0. PMID 12575992.66-9&rft.date=2003-02&rft_id=info:doi/10.1016/S0968-0004(02)50013-0&rft_id=info:pmid/12575992&rft.aulast=Roussigne&rft.aufirst=M&rft.au=Kossida, S&rft.au=Lavigne, AC&rft.au=Clouaire, T&rft.au=Ecochard, V&rft.au=Glories, A&rft.au=Amalric, F&rft.au=Girard, JP&rfr_id=info:sid/en.wikipedia.org:THAP2" class="Z3988">
^ "Entrez Gene: THAP2 THAP domain containing, apoptosis associated protein 2".

Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.2136-44&rft.date=2004&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC528930#id-name=PMC&rft_id=info:pmid/15489336&rft_id=info:doi/10.1101/gr.2576704&rft.au=Wiemann S&rft.au=Arlt D&rft.au=Huber W&rft.au=Wellenreuther, R&rft.au=Schleeger, S&rft.au=Mehrle, A&rft.au=Bechtel, S&rft.au=Sauermann, M&rft.au=Korf, U&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC528930&rfr_id=info:sid/en.wikipedia.org:THAP2" class="Z3988">
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.2121-7&rft.date=2004&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC528928#id-name=PMC&rft_id=info:pmid/15489334&rft_id=info:doi/10.1101/gr.2596504&rft.au=Gerhard DS&rft.au=Wagner L&rft.au=Feingold EA&rft.au=Shenmen, CM&rft.au=Grouse, LH&rft.au=Schuler, G&rft.au=Klein, SL&rft.au=Old, S&rft.au=Rasooly, R&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC528928&rfr_id=info:sid/en.wikipedia.org:THAP2" class="Z3988">
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.16899-903&rft.date=2003&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139241#id-name=PMC&rft_id=info:pmid/12477932&rft_id=info:doi/10.1073/pnas.242603899&rft_id=info:bibcode/2002PNAS...9916899M&rft.au=Strausberg RL&rft.au=Feingold EA&rft.au=Grouse LH&rft.au=Derge, JG&rft.au=Klausner, RD&rft.au=Collins, FS&rft.au=Wagner, L&rft.au=Shenmen, CM&rft.au=Schuler, GD&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139241&rfr_id=info:sid/en.wikipedia.org:THAP2" class="Z3988">
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.287-92&rft.date=2001&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1083732#id-name=PMC&rft_id=info:pmid/11256614&rft_id=info:doi/10.1093/embo-reports/kvd058&rft.au=Simpson JC&rft.au=Wellenreuther R&rft.au=Poustka A&rft.au=Pepperkok, R&rft.au=Wiemann, S&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1083732&rfr_id=info:sid/en.wikipedia.org:THAP2" class="Z3988">
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.422-35&rft.date=2001&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC311072#id-name=PMC&rft_id=info:pmid/11230166&rft_id=info:doi/10.1101/gr.GR1547R&rft.au=Wiemann S&rft.au=Weil B&rft.au=Wellenreuther R&rft.au=Gassenhuber, J&rft.au=Glassl, S&rft.au=Ansorge, W&rft.au=Böcher, M&rft.au=Blöcker, H&rft.au=Bauersachs, S&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC311072&rfr_id=info:sid/en.wikipedia.org:THAP2" class="Z3988">
Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.1788-95&rft.date=2001&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC310948#id-name=PMC&rft_id=info:pmid/11076863&rft_id=info:doi/10.1101/gr.143000&rft.aulast=Hartley&rft.aufirst=JL&rft.au=Temple, GF&rft.au=Brasch, MA&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC310948&rfr_id=info:sid/en.wikipedia.org:THAP2" class="Z3988">

This article on a gene on human chromosome 12 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000173451 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000020137 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12575992-5] Roussigne M, Kossida S, Lavigne AC, Clouaire T, Ecochard V, Glories A, Amalric F, Girard JP (Feb 2003). "The THAP domain: a novel protein motif with similarity to the DNA-binding domain of P element transposase". Trends Biochem Sci. 28 (2): 66–9. doi:10.1016/S0968-0004(02)00013-0. PMID 12575992.66-9&rft.date=2003-02&rft_id=info:doi/10.1016/S0968-0004(02)50013-0&rft_id=info:pmid/12575992&rft.aulast=Roussigne&rft.aufirst=M&rft.au=Kossida, S&rft.au=Lavigne, AC&rft.au=Clouaire, T&rft.au=Ecochard, V&rft.au=Glories, A&rft.au=Amalric, F&rft.au=Girard, JP&rfr_id=info:sid/en.wikipedia.org:THAP2" class="Z3988">

[entrez-6] "Entrez Gene: THAP2 THAP domain containing, apoptosis associated protein 2".

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References

Further reading