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Protein-coding gene in the species Homo sapiens
SEC14L2 is a gene that, in humans, encodes the protein SEC14-like protein 2 .[ 5] [ 6]
This gene encodes a cytosolic protein which belongs to a family of lipid-binding proteins including Sec14p, alpha-tocopherol transfer protein , and cellular retinol-binding protein . The encoded protein stimulates squalene monooxygenase which is a downstream enzyme in metabolism of cholesterol .[ 6]
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PDB gallery
1o6u : THE CRYSTAL STRUCTURE OF HUMAN SUPERNATANT PROTEIN FACTOR
1olm : SUPERNATANT PROTEIN FACTOR IN COMPLEX WITH RRR-ALPHA-TOCOPHERYLQUINONE: A LINK BETWEEN OXIDIZED VITAMIN E AND CHOLESTEROL BIOSYNTHESIS
