60S ribosomal protein L9

RPL9
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2CQL, 4UG0, 4V6X, 5AJ0, 3J92, 4UJC, 3J7P, 4UJE, 3J7Q, 3J7R, 4D67, 4UJD, 4V5Z, 4D5Y, 3J7O
Identifiers
Aliases	RPL9, L9, NPC-A-16, ribosomal protein L9
External IDs	OMIM: 603686; MGI: 1298373; HomoloGene: 90855; GeneCards: RPL9; OMA:RPL9 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	39,458,931 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	65,548,787 bp
RNA expression pattern
	Top expressed in
	left ovary; ; right ovary; ; gastric mucosa; ; Achilles tendon; ; right uterine tube; ; ganglionic eminence; ; lactiferous gland; ; corpus callosum; ; olfactory zone of nasal mucosa; ; gallbladder;
	Top expressed in
	dentate gyrus of hippocampal formation granule cell; ; ventricular zone; ; blastocyst; ; embryo; ; embryo; ; morula; ; lip; ; superior frontal gyrus; ; primary visual cortex; ; spermatocyte;
	More reference expression data
	n/a
Gene ontology
Molecular function	rRNA binding; protein binding; RNA binding; structural constituent of ribosome;
Cellular component	cytosol; ribosome; membrane; focal adhesion; intracellular anatomical structure; cytosolic large ribosomal subunit; nucleus; extracellular matrix;
Biological process	cytoplasmic translation; protein biosynthesis; viral transcription; SRP-dependent cotranslational protein targeting to membrane; translational initiation; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; rRNA processing;
	Sources:Amigo / QuickGO
Orthologs
	6133
	20005
	ENSG00000163682
	ENSMUSG00000047215
	P32969
	P51410
	NM_000661; NM_001024921
	NM_011292
	NP_000652; NP_001020092
	NP_035422
	Wikidata
View/Edit Human	View/Edit Mouse

60S ribosomal protein L9 is a protein that in humans is encoded by the RPL9 gene.^[5]^[6]^[7]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L6P family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000163682 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000047215 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mazuruk K, Schoen TJ, Chader GJ, Iwata T, Rodriguez IR (Apr 1996). "Structural organization and chromosomal localization of the human ribosomal protein L9 gene". Biochim Biophys Acta. 1305 (3): 151–62. doi:10.1016/0167-4781(95)00201-4. PMID 8597601.151-62&rft.date=1996-04&rft_id=info:doi/10.1016/0167-4781(95)00201-4&rft_id=info:pmid/8597601&rft.aulast=Mazuruk&rft.aufirst=K&rft.au=Schoen, TJ&rft.au=Chader, GJ&rft.au=Iwata, T&rft.au=Rodriguez, IR&rfr_id=info:sid/en.wikipedia.org:60S ribosomal protein L9" class="Z3988">
^ Hori N, Murakawa K, Matoba R, Fukushima A, Okubo K, Matsubara K (Nov 1993). "A new human ribosomal protein sequence, homologue of rat L9". Nucleic Acids Res. 21 (18): 4395. doi:10.1093/nar/21.18.4395. PMC 310081. PMID 8415001.
^ ^a ^b "Entrez Gene: RPL9 ribosomal protein L9".

Wool IG, Chan YL, Glück A (1996). "Structure and evolution of mammalian ribosomal proteins". Biochem. Cell Biol. 73 (11–12): 933–47. doi:10.1139/o95-101. PMID 8722009.11–12&rft.pages=933-47&rft.date=1996&rft_id=info:doi/10.1139/o95-101&rft_id=info:pmid/8722009&rft.aulast=Wool&rft.aufirst=IG&rft.au=Chan, YL&rft.au=Glück, A&rfr_id=info:sid/en.wikipedia.org:60S ribosomal protein L9" class="Z3988">
Kenmochi N, Kawaguchi T, Rozen S, et al. (1998). "A map of 75 human ribosomal protein genes". Genome Res. 8 (5): 509–23. doi:10.1101/gr.8.5.509. PMID 9582194.509-23&rft.date=1998&rft_id=info:doi/10.1101/gr.8.5.509&rft_id=info:pmid/9582194&rft.aulast=Kenmochi&rft.aufirst=N&rft.au=Kawaguchi, T&rft.au=Rozen, S&rft_id=https://doi.org/10.1101%2Fgr.8.5.509&rfr_id=info:sid/en.wikipedia.org:60S ribosomal protein L9" class="Z3988">
Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. Bibcode:2002CBio...12....1A. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033.1-11&rft.date=2002&rft_id=info:doi/10.1016/S0960-9822(01)00650-9&rft_id=https://api.semanticscholar.org/CorpusID:14132033#id-name=S2CID&rft_id=info:pmid/11790298&rft_id=info:bibcode/2002CBio...12....1A&rft.aulast=Andersen&rft.aufirst=JS&rft.au=Lyon, CE&rft.au=Fox, AH&rft_id=https://doi.org/10.1016%2FS0960-9822%2801%2900650-9&rfr_id=info:sid/en.wikipedia.org:60S ribosomal protein L9" class="Z3988">
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.16899-903&rft.date=2003&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139241#id-name=PMC&rft_id=info:pmid/12477932&rft_id=info:doi/10.1073/pnas.242603899&rft_id=info:bibcode/2002PNAS...9916899M&rft.aulast=Strausberg&rft.aufirst=RL&rft.au=Feingold, EA&rft.au=Grouse, LH&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139241&rfr_id=info:sid/en.wikipedia.org:60S ribosomal protein L9" class="Z3988">
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.2121-7&rft.date=2004&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC528928#id-name=PMC&rft_id=info:pmid/15489334&rft_id=info:doi/10.1101/gr.2596504&rft.aulast=Gerhard&rft.aufirst=DS&rft.au=Wagner, L&rft.au=Feingold, EA&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC528928&rfr_id=info:sid/en.wikipedia.org:60S ribosomal protein L9" class="Z3988">
Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.77-83&rft.date=2005&rft_id=info:doi/10.1038/nature03207&rft_id=https://api.semanticscholar.org/CorpusID:4344740#id-name=S2CID&rft_id=info:pmid/15635413&rft_id=info:bibcode/2005Natur.433...77A&rft.aulast=Andersen&rft.aufirst=JS&rft.au=Lam, YW&rft.au=Leung, AK&rfr_id=info:sid/en.wikipedia.org:60S ribosomal protein L9" class="Z3988">
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.1173-8&rft.date=2005&rft_id=info:doi/10.1038/nature04209&rft_id=https://api.semanticscholar.org/CorpusID:4427026#id-name=S2CID&rft_id=info:pmid/16189514&rft_id=info:bibcode/2005Natur.437.1173R&rft.aulast=Rual&rft.aufirst=JF&rft.au=Venkatesan, K&rft.au=Hao, T&rfr_id=info:sid/en.wikipedia.org:60S ribosomal protein L9" class="Z3988">
Oh JH, Yang JO, Hahn Y, et al. (2006). "Transcriptome analysis of human gastric cancer". Mamm. Genome. 16 (12): 942–54. doi:10.1007/s00335-005-0075-2. PMID 16341674. S2CID 69278.942-54&rft.date=2006&rft_id=https://api.semanticscholar.org/CorpusID:69278#id-name=S2CID&rft_id=info:pmid/16341674&rft_id=info:doi/10.1007/s00335-005-0075-2&rft.aulast=Oh&rft.aufirst=JH&rft.au=Yang, JO&rft.au=Hahn, Y&rfr_id=info:sid/en.wikipedia.org:60S ribosomal protein L9" class="Z3988">

External links

PDBe-KB provides an overview of all the structure information available in the PDB for Human 60S ribosomal protein L9

This article on a gene on human chromosome 4 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000163682 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000047215 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8597601-5] Mazuruk K, Schoen TJ, Chader GJ, Iwata T, Rodriguez IR (Apr 1996). "Structural organization and chromosomal localization of the human ribosomal protein L9 gene". Biochim Biophys Acta. 1305 (3): 151–62. doi:10.1016/0167-4781(95)00201-4. PMID 8597601.151-62&rft.date=1996-04&rft_id=info:doi/10.1016/0167-4781(95)00201-4&rft_id=info:pmid/8597601&rft.aulast=Mazuruk&rft.aufirst=K&rft.au=Schoen, TJ&rft.au=Chader, GJ&rft.au=Iwata, T&rft.au=Rodriguez, IR&rfr_id=info:sid/en.wikipedia.org:60S ribosomal protein L9" class="Z3988">

[pmid8415001-6] Hori N, Murakawa K, Matoba R, Fukushima A, Okubo K, Matsubara K (Nov 1993). "A new human ribosomal protein sequence, homologue of rat L9". Nucleic Acids Res. 21 (18): 4395. doi:10.1093/nar/21.18.4395. PMC 310081. PMID 8415001.

[entrez-7] "Entrez Gene: RPL9 ribosomal protein L9".

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References

Further reading

External links