Perfluoropentane

Perfluoropentane
Names
	Preferred IUPAC name Dodecafluoropentane
	Other names Perfluoropentane
Identifiers
CAS Number	678-26-2;
3D model (JSmol)	Interactive image;
Beilstein Reference	1712388
ChEBI	CHEBI:39428;
ChEMBL	ChEMBL1899801;
ChemSpider	12154;
ECHA InfoCard	100.010.589
EC Number	211-647-5;
KEGG	D05436;
PubChem CID	12675;
UNII	483AU1Y5CZ;
CompTox Dashboard (EPA)	DTXSID3046613 ;
	InChI InChI=1S/C5F12/c6-1(7,2(8,9)4(12,13)14)3(10,11)5(15,16)17 Key: NJCBUSHGCBERSK-UHFFFAOYSA-N; InChI=1/C5F12/c6-1(7,2(8,9)4(12,13)14)3(10,11)5(15,16)17 Key: NJCBUSHGCBERSK-UHFFFAOYAH;
	SMILES C(C(C(F)(F)F)(F)F)(C(C(F)(F)F)(F)F)(F)F;
Properties
Chemical formula	C5F12
Molar mass	288.036 g·mol−1
Density	1.63 g/mL (liquid, 25 °C); 1.59 g/mL (liquid, 35 °C); 12.25 kg/m³ (gas, 1 atm, 10 times air density)
Melting point	−115 °C (−175 °F; 158 K)
Boiling point	28 °C (82 °F; 301 K) ; Heat of vaporization = 21 cal/g
Vapor pressure	83.99 kPa (25 °C)
Viscosity	0.652 mPa*s (25 °C)
Thermochemistry
Heat capacity (C)	0.26 cal/(g • K)
Pharmacology
ATC code	V08DA03 (WHO)
Hazards
	GHS labelling:
Pictograms
Signal word	Warning
Hazard statements	H315, H319, H335
Precautionary statements	P261, P264, P271, P280, P302 P352, P304 P340, P305 P351 P338, P312, P321, P332 P313, P337 P313, P362, P403 P233, P405, P501
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Perfluoropentane (PFP) or dodecafluoropentane; also known as Perflenapent (INN/USAN) is a fluorocarbon, the fluorinated analogue of pentane. It is a liquid that boils at slightly over room temperature.

It has several biomedical applications including: propellant for pressurized metered dose inhalers;^[3] gas core in microbubble ultrasound contrast agents;^[4] and occlusion therapy via the conversion of nanometer liquid droplets into micrometer sized gas microbubbles (acoustic droplet vaporization).^[5]

References

^ "Front Matter". Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book). Cambridge: The Royal Society of Chemistry. 2014. p. 33. doi:10.1039/9781849733069-FP001. ISBN 978-0-85404-182-4. The prefix 'per-' is no longer recommended.
^ "Perfluoropentane". Retrieved September 26, 2023.
^ Rogueda, P. G. A. HPFP, a Model Propellant for pMDIs. Drug Dev. Ind. Phar. 2003, 29, 39
^ Liu, Y., Miyoshi, H., and Nakamura, M. Encapsulated ultrasound microbubbles: Therapeutic application in drug/gene delivery. J. Controlled Release 2006, 114, 89− 99
^ D. Bardin, T. D. Martz, P. S. Sheeran, R. Shih, P. A. Dayton, and A. P. Lee, “High-speed, clinical-scale microfluidic generation of stable phase-change droplets for gas embolotherapy,” Lab on a Chip, vol. 11, no. 23, p. 3990, 2011.

This pharmacology-related article is a stub. You can help Wikipedia by expanding it.

[iupac2013-1] "Front Matter". Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book). Cambridge: The Royal Society of Chemistry. 2014. p. 33. doi:10.1039/9781849733069-FP001. ISBN 978-0-85404-182-4. The prefix 'per-' is no longer recommended.

[fluoromed-2] "Perfluoropentane". Retrieved September 26, 2023.

[3] Rogueda, P. G. A. HPFP, a Model Propellant for pMDIs. Drug Dev. Ind. Phar. 2003, 29, 39

[4] Liu, Y., Miyoshi, H., and Nakamura, M. Encapsulated ultrasound microbubbles: Therapeutic application in drug/gene delivery. J. Controlled Release 2006, 114, 89− 99

[5] D. Bardin, T. D. Martz, P. S. Sheeran, R. Shih, P. A. Dayton, and A. P. Lee, “High-speed, clinical-scale microfluidic generation of stable phase-change droplets for gas embolotherapy,” Lab on a Chip, vol. 11, no. 23, p. 3990, 2011.

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