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Protein-coding gene in the species Homo sapiens
U4/U6 small nuclear ribonucleoprotein Prp4 is a protein that in humans is encoded by the PRPF4 gene .[ 5] [ 6] [ 7]
The removal of introns from nuclear pre-mRNAs occurs on complexes called spliceosomes , which are made up of 4 small nuclear ribonucleoprotein (snRNP) particles and an undefined number of transiently associated splicing factors. PRPF4 is 1 of several proteins that associate with U4 and U6 snRNPs.[supplied by OMIM ][ 7]
^ a b c GRCh38: Ensembl release 89: ENSG00000136875 – Ensembl , May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000066148 – Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
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^ Horowitz DS, Kobayashi R, Krainer AR (Dec 1997). "A new cyclophilin and the human homologues of yeast Prp3 and Prp4 form a complex associated with U4/U6 snRNPs" . RNA . 3 (12): 1374–87. PMC 1369579 . PMID 9404889 .
^ a b "Entrez Gene: PRPF4 PRP4 pre-mRNA processing factor 4 homolog (yeast)" .
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