NKG2
Appearance
killer cell lectin-like receptor subfamily C, member 1 | |||||||
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Identifiers | |||||||
Symbol | KLRC1 | ||||||
Alt. symbols | NKG2, NKG2-A, NKG2-B, CD159a | ||||||
NCBI gene | 3821 | ||||||
HGNC | 6374 | ||||||
OMIM | 161555 | ||||||
RefSeq | NM_007328 | ||||||
UniProt | P26715 | ||||||
Other data | |||||||
Locus | Chr. 12 p13 | ||||||
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NKG2 also known as CD159 (Cluster of Differentiation 159) is a receptor for natural killer cells. There are 7 NKG2 types: A, B, C, D, E, F and H. NKG2D is an activating receptor on the NK cell surface. NKG2A dimerizes with CD94 to make an inhibitory receptor (CD94/NKG2).
IPH2201 is a monoclonal antibody targeted at NKG2A.[1]
See also
References
External links
- NKG2 protein at the U.S. National Library of Medicine Medical Subject Headings (MeSH)