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Indolin-2-one monooxygenase

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Indolin-2-one monooxygenase
Identifiers
EC no.1.14.13.138
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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NCBIproteins

Indolin-2-one monooxygenase (EC 1.14.13.138, BX3 (gene), CYP71C2 (gene)) is an enzyme with systematic name indolin-2-one,NAD(P)H:oxygen oxidoreductase (3-hydroxylating).[1][2] This enzyme catalyses the following chemical reaction

indolin-2-one NAD(P)H H O2 3-hydroxyindolin-2-one NAD(P) H2O

Indolin-2-one monooxygenase is involved in the biosynthesis of protective and allelopathic benzoxazinoids in some plants.

References

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  1. ^ Frey M, Chomet P, Glawischnig E, Stettner C, Grün S, Winklmair A, Eisenreich W, Bacher A, Meeley RB, Briggs SP, Simcox K, Gierl A (August 1997). "Analysis of a chemical plant defense mechanism in grasses". Science. 277 (5326): 696–9. doi:10.1126/science.277.5326.696. PMID 9235894.
  2. ^ Glawischnig E, Grün S, Frey M, Gierl A (March 1999). "Cytochrome P450 monooxygenases of DIBOA biosynthesis: specificity and conservation among grasses". Phytochemistry. 50 (6): 925–30. Bibcode:1999PChem..50..925G. doi:10.1016/s0031-9422(98)00318-5. PMID 10385992.
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