Fructuronate reductase
| fructuronate reductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.57 | ||||||||
| CAS no. | 9028-44-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a fructuronate reductase (EC 1.1.1.57) is an enzyme that catalyzes the chemical reaction
- D-mannonate NAD D-fructuronate NADH H
Thus, the two substrates of this enzyme are D-mannonate and NAD , whereas its 3 products are D-fructuronate, NADH, and H .
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD or NADP as acceptor. The systematic name of this enzyme class is D-mannonate:NAD 5-oxidoreductase. Other names in common use include mannonate oxidoreductase, mannonic dehydrogenase, D-mannonate dehydrogenase, and D-mannonate:NAD oxidoreductase. This enzyme participates in pentose and glucuronate interconversions.
References
[edit]- Hickman J; Ashwell G (1960). "Uronic acid metabolism in bacteria. II. Purification and properties of D-altronic acid and D-mannonic acid dehyrogenases in Escherichia coli". J. Biol. Chem. 235: 1566–1570.
- Kilgore WW, Starr MP (1959). "Catabolism of galacturonic and glucuronic acids by Erwinia carotovora". J. Biol. Chem. 234: 2227–35. PMID 14409051.
