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ARHGAP4

From Wikipedia, the free encyclopedia
ARHGAP4
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
AliasesARHGAP4, C1, RGC1, RhoGAP4, SrGAP4, p115, Rho GTPase activating protein 4
External IDsOMIM: 300023; MGI: 2159577; HomoloGene: 20403; GeneCards: ARHGAP4; OMA:ARHGAP4 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001666
NM_001164741

NM_001162423
NM_001162424
NM_138630

RefSeq (protein)

NP_001158213
NP_001657

n/a

Location (UCSC)Chr X: 153.91 – 153.93 MbChr X: 72.94 – 72.97 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Rho GTPase-activating protein 4 is an enzyme that in humans is encoded by the ARHGAP4 gene.[5][6] It has been shown to regulate cell motility and axonal outgrowth in vitro.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000089820Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000031389Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Tribioli C, Droetto S, Bione S, Cesareni G, Torrisi MR, Lotti LV, Lanfrancone L, Toniolo D, Pelicci P (Mar 1996). "An X chromosome-linked gene encoding a protein with characteristics of a rhoGAP predominantly expressed in hematopoietic cells". Proc Natl Acad Sci U S A. 93 (2): 695–9. Bibcode:1996PNAS...93..695T. doi:10.1073/pnas.93.2.695. PMC 40115. PMID 8570618.
  6. ^ "Entrez Gene: ARHGAP4 Rho GTPase activating protein 4".
  7. ^ Vogt, DL; Gray, CD; Young Ws, 3rd; Orellana, SA; Malouf, AT (2007). "ARHGAP4 is a novel RhoGAP that mediates inhibition of cell motility and axon outgrowth". Molecular and Cellular Neurosciences. 36 (3): 332–42. doi:10.1016/j.mcn.2007.07.004. PMC 2111057. PMID 17804252.{{cite journal}}: CS1 maint: numeric names: authors list (link)
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Further reading

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